>혈액 악성종양에 대한 CAR 표적
인간, 마우스, 원숭이, 토끼 등을 포함하는 다양한 종
FACS/ELISA/SPR로 검증된 높은 생체 활성
Star Staining-Alexa Fluor 488/555/647, PE, APC, FITC 라벨 이용 가능
일부 제품은 IND, NDA 및 BLA 지원을 위해 FDA DMF 제출
The purity of Human CD4, Fc Tag (MALS verified) (Cat. No. CD4-H5259) is more than 95% and the molecular weight of this protein is around 150-170 kDa verified by SEC-MALS.
Immobilized Human / Cynomolgus / Rhesus macaque ROR1, Fc Tag (Cat. No. RO1-H5250) at 2 μg/mL (100 μL/well) can bind Anti-ROR1 Antibody, Human IgG1 with a linear range of 0.3-5 ng/mL (QC tested).
Immobilized Human Siglec-2, Fc Tag (Cat. No. CD2-H5253) at 2 μg/mL (100 μL/well) can bind Monoclonal Anti-Human Siglec-2 Antibody, Human IgG1 with a linear range of 2-62.5 ng/mL (QC tested).
Binding activity of FITC-Labeled Human BCMA and CD19 protein from two different vendors were evaluated by the FACS analysis. The result showed that ACRO's Star Staining FITC-Labeled Human BCMA (Cat. No. BCA-HF2H3) and CD19 (Cat. No. CD9-HF2H3) protein have a much higher binding activity than that of the other competitor.
5e5 of PBMCs were stained with AF555-Labeled Human CD19 (20-291), His Tag (Cat. No. CD9-HA2H7) and anti-CD3 antibody, washed and then analyzed with FACS. FITC signal was used to evaluate the expression of CD3+ T cells in PBMCs, and AF555 signal was used to evaluate the non-specific binding activity to PBMCs (QC tested).
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