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World Ankylosing Spondylitis Day | ACRO Stands with You in Safeguarding Spinal Health
We have developed a comprehensive product portfolio including highly active recombinant proteins, stable cell lines, and inhibitor screening kits, to accelerate the efficient translation of AS innovative therapies from foundational research to clinical implementation.
2025/04/28     Read: 44
Multispecific Antibodies: Advancing Precision Immunotherapy in Cancer Treatment
From monoclonal antibodies to multispecific antibodies (MsAbs), the development of antibody drugs has greatly enhanced the precision and efficacy of cancer immunotherapy. Bispecific antibodies strengthen tumor-killing ability through a dual-target mechanism, trispecific antibodies further optimize i
2025/03/20     Read: 655
Key Factors in Antibody Drug Development
Key Factors in Antibody Drug Development (Half-Life Assessment and In Vitro Functional Validation)
2025/04/22     Read: 132
From Animals to Organoids: The Future of Drug Testing
Recently, the FDA announced a landmark decision to phase out mandatory animal testing for monoclonal antibodies and other drugs, encouraging New Approach Methodologies like organoids for safer, more efficient drug development. Organoids—lab-grown mini-organs—better mimic human biology, making them i
2025/04/22     Read: 179
Evaluating Therapeutic Efficacy in Autoimmune Disease Biologic Development
Biomarkers play a vital role in the development of biological drugs, offering insights into drug mechanisms of action (MOA), guiding clinical study design, and optimizing treatment strategies. Widely used across early discovery, preclinical, and clinical stages, biomarkers ensure precise dosing, eff
2025/04/21     Read: 166
Soluble B-cell maturation antigen (sBCMA) plays a dual role in targeted immunotherapy
B-cell maturation antigen (BCMA), encoded by the TNFRSF17 gene located on the short arm of chromosome 16, is a type III transmembrane glycoprotein predominantly expressed on the surface of plasma cells and myeloma cells. Under the action of specific enzymes, such as γ-secretase, the extracellular do
2025/04/21     Read: 137
Differentiating Cytokine Detection Strategies in CAR-T vs. CAR-NK Therapies
Cellular immunotherapies, including CAR-T and CAR-NK therapies, leverage engineered immune cells to combat cancer. While both modalities share similarities, their distinct biological mechanisms necessitate tailored approaches to cytokine and biomarker detection. CAR-T therapies heavily rely on IFN-γ
2025/04/21     Read: 111
In Vitro Activity Evaluation of TCE Drug-Cytokines Detection
T Cell Engagers (TCEs) are bispecific antibodies that simultaneously target tumor-associated cell surface antigens (Tumor-Associated Antigens, TAA) and T-cell surface receptors (T-Cell Receptor, TCR). Compared to traditional monoclonal antibodies, a significant advantage of TCE bispecific antibodies
2025/04/21     Read: 100
Unlocking Parkinson's Disease: From Disease Mechanisms to Precision Treatment
Parkinson’s disease (PD) is a complex neurodegenerative disorder marked by dopaminergic neuron (DN) loss and α-synuclein aggregation. Key molecules like α-synuclein, MAO-B, and ADORA2A play critical roles in disease progression. iPSC-derived DNs and brain organoids improve the physiological relevanc
2025/04/17     Read: 216
Asthma Targeted Therapy: The Breakthrough Strategy for the Billion-Dollar Market
We have developed a range of products targeting core mechanisms in asthma pathology, including recombinant proteins, cell lines, and inhibitor screening kits of TSLP/TSLPR, IL-4/IL-4R, IL-5/IL-5R, IL-13/IL-13R, IL-6/IL-6R, IL-8, IL-17/IL-17R, IL-33, and IgE Fc, to comprehensively support the develop
2025/04/17     Read: 202
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