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BCMA

요약

Name:B-cell maturation protein
Target Synonym:B-Cell Maturation Protein,B-Cell Maturation Factor,B Cell Maturation Antigen,CD269 Antigen,Tumor Necrosis Factor Receptor Superfamily Member 17,TNFRSF17,TNFRSF13A,CD269,BCM,BCMA,TNF Receptor Superfamily Member 17,Tumor Necrosis Factor Receptor Superfamily, Member 17,B-Cell Maturation Antigen
Number of Launched Drugs:7
Number of Drugs in Clinical Trials:117
Lastest Research Phase:Phase 3 Clinical

제품 리스트 구매

제품번호 제품 설명 구조 순도 특징
CHEK-ATP218 Human HEK293/Human BCMA Stable Cell Line
CEA-B045 Human ClinMax™ Human Soluble BCMA ELISA Kit
MBS-C004 Human ActiveMax® Human BCMA μBeads, premium grade (for cells)
BCA-HA2H7 Human Alexa Fluor™ 555-Labeled Human BCMA / TNFRSF17 Protein, His TagStar Staining
BCA-HA2H7-structure
BCA-HA2H9 Human Alexa Fluor™ 647-Labeled Human BCMA / TNFRSF17 Protein, His TagStar Staining
BCA-HA2H9-structure
BCA-HA2H8 Human Alexa Fluor™ 488-Labeled Human BCMA / TNFRSF17 Protein, His TagStar Staining
BCA-HA2H8-structure
BCA-HA2H5 Human APC-Labeled Human BCMA / TNFRSF17 Protein, His Tag (Site-specific conjugation)
BCA-HA2H5-structure
BCA-HA2H4 Human APC-Labeled Human BCMA / TNFRSF17 Protein, His TagStar Staining
BCA-HA2H4-structure
BCA-HP2H7 Human PE-Labeled Human BCMA / TNFRSF17 Protein, His TagStar Staining
BCA-HP2H7-structure
BCA-C5257 Cynomolgus / Rhesus macaque Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, Llama IgG2b Fc Tag, low Endotoxin (MALS verified)
BCA-C5257-structure
BCA-C5257-sds
BCA-HF2H3 Human FITC-Labeled Human BCMA / TNFRSF17 Protein, His TagStar Staining
BCA-HF2H3-structure
BCA-HF2H3-sds
BCA-C52H3 Canine Canine BCMA / TNFRSF17 Protein, His Tag (MALS verified)
BCA-C52H3-structure
BCA-C52H3-sds
BCA-R52H3 Rat Rat BCMA / TNFRSF17 Protein, His Tag
BCA-R52H3-structure
BCA-R52H3-sds
BCA-R52H4 Rabbit Rabbit BCMA / TNFRSF17 Protein, His Tag
BCA-R52H4-structure
BCA-R52H4-sds
BCA-HP2H2 Human PE-Labeled Human BCMA / TNFRSF17 Protein, His Tag (Site-specific conjugation)
BCA-HP2H2-structure
BCA-C82E5 Cynomolgus / Rhesus macaque Biotinylated Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, His,Avitag™
BCA-C82E5-structure
BCA-C82E5-sds
BCA-M43 Mouse Anti-BCMA Neutralizing Antibody, Mouse IgG1 (recommended for neutralizing assay)
BCA-M43-sds
MBS-K004 Human Human BCMA-coupled Magnetic Beads
BCA-HF2H1 Human FITC-Labeled Human BCMA / TNFRSF17 Protein, His Tag
BCA-HF2H1-structure
BCA-HF2H1-sds
BCA-H5253 Human Human BCMA / TNFRSF17 Protein, Mouse IgG2a Fc Tag, low endotoxin
BCA-H5253-structure
BCA-H5253-sds
BCA-M52H3 Mouse Mouse BCMA / TNFRSF17 Protein, His Tag
BCA-M52H3-structure
BCA-M52H3-sds
BCA-H82E4 Human Biotinylated Human BCMA / TNFRSF17 Protein, His,Avitag™, premium grade
BCA-H82E4-structure
BCA-H82E4-sds
BCA-H82E4-hplc
BCA-H5259 Human Human BCMA / TNFRSF17 Protein, Llama IgG2b Fc Tag, low endotoxin
BCA-H5259-structure
BCA-H5259-sds
BCA-C52H7 Cynomolgus / Rhesus macaque Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, His Tag (MALS verified)
BCA-C52H7-structure
BCA-C52H7-sds
BCA-M82F0 Mouse Biotinylated Mouse BCMA / TNFRSF17 Protein, Fc,Avitag™
BCA-M82F0-structure
BCA-M82F0-sds
BCA-M5258 Mouse Mouse BCMA / TNFRSF17 Protein, Fc Tag
BCA-M5258-structure
BCA-M5258-sds
BCA-C5253 Cynomolgus / Rhesus macaque Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, Fc Tag
BCA-C5253-structure
BCA-C5253-sds
BCA-C82F4 Cynomolgus / Rhesus macaque Biotinylated Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, Fc,Avitag™
BCA-C82F4-structure
BCA-C82F4-sds
BC7-H82F0 Human Biotinylated Human BCMA / TNFRSF17 Protein, Fc,Avitag™, premium grade
BC7-H82F0-structure
BC7-H82F0-sds
BCA-H522y Human Human BCMA / TNFRSF17 Protein, His Tag, premium grade
BCA-H522y-structure
BCA-H522y-sds
BCA-H522y-hplc
BCA-HF254 Human FITC-Labeled Human BCMA / TNFRSF17 Protein, Fc Tag
BCA-HF254-structure
BCA-HF254-sds
BC7-H5254 Human Human BCMA / TNFRSF17 Protein, Fc Tag, premium grade
BC7-H5254-structure
BC7-H5254-sds
BC7-H5254-hplc

일부의 생물활성 데이터

BCA-HA2H5-Cell-based assay
 BCMA FACS

5e5 of anti-BCMA CAR-293 cells were stained with 100 μL of 1:50 dilution (2 μL stock solution in 100 μL FACS buffer) of APC-Labeled Human BCMA, His Tag (Cat. No. BCA-HA2H5) and negative control protein respectively. APC signal was used to evaluate the binding activity (QC tested).

BCA-HP2H2-Cell-based assay
 BCMA FACS

1e6 of the Anti-BCMA CAR-293 cells were stained with 100 μL of 1:50 dilution (2 μL stock solution in 100 μL FACS buffer) of PE-Labeled Human BCMA Protein, His Tag (Cat. No. BCA-HP2H2) and negative control protein respectively, PE signal was used to evaluate the binding activity (QC tested).

BCA-M43-SPR
 BCMA SPR

Anti-BCMA Neutralizing Antibody, Mouse IgG1 (Clone: AM43, Cat. No. BCA-M43) captured on CM5 chip via anti-mouse antibodies surface can bind Human BCMA, His Tag (Cat. No. BCA-H522y) with an affinity constant of 0.388 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

BCA-H522y-SPR
 BCMA SPR

Anti-Human BCMA MAb (human IgG1) captured on CM5 chip via Anti-Human IgG Fc antibodies surface, can bind Human BCMA, His Tag, premium grade (Cat. No. BCA-H522y) with an affinity constant of 13.0 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

사용자 리뷰

Synonym Name

TNFRSF17,CD269,BCM,BCMA

Background

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

Clinical and Translational Updates

Related Molecule

공개 약품 정보

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Belantamab mafodotin GSK-2857916; GSK2857916 Approved Glaxosmithkline Plc BLENREP Mainland China(BOAO LECHENG) Multiple Myeloma Glaxosmithkline Plc 2020-08-05 Bone Marrow Neoplasms; Lymphoma, B-Cell; Hematologic Diseases; Paraproteinemias; Immunoglobulin Light-chain Amyloidosis; Plasmacytoma; Corneal Diseases; Neoplasms; Blood Protein Disorders; Multiple Myeloma; Plasmablastic Lymphoma; Neoplasms, Plasma Cell; Amyloidosis Details
Idecabtagene vicleucel bb-2121 Approved Bluebird Bio Inc Abecma United States Multiple Myeloma Celgene Corp 2021-03-26 Multiple Myeloma Details
Zevorcabtagene Autoleucel CT-053-CARsgen Approved Carsgen Biomedicine (Shanghai) Co Ltd 赛恺泽 Mainland China Multiple Myeloma Kaixing Life Technology (Shanghai) Co Ltd 2024-02-23 Multiple Myeloma Details
Equecabtagene Autoleucel IBI-326; CT-103A; CT103A Approved Nanjing Iaso Biotherapeutics Co Ltd, Innovent Biologics(Suzhou) Co Ltd 福可苏, FUCASO Mainland China Multiple Myeloma Nanjing Xunlu Biomedicine Co Ltd 2023-06-30 Myasthenia Gravis; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Myositis; Autoimmune Diseases; Multiple Sclerosis; Multiple Myeloma; Lupus Nephritis; Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease; Neuromyelitis Optica; Lupus Erythematosus, Systemic; POEMS Syndrome; Autoimmune Diseases of the Nervous System; Encephalitis Details
Teclistamab JNJ-64007957; JNJ-64007959; JNJ-7957 Approved Genmab A/S, Johnson & Johnson Innovative Medicine TECAYLI, TECVAYLI, 泰立珂 EU Multiple Myeloma Janssen-Cilag International Nv 2022-08-23 Hematologic Diseases; Immunoglobulin Light-chain Amyloidosis; Smoldering Multiple Myeloma; Multiple Myeloma Details
Ciltacabtagene autoleucel JNJ-4528; LCAR-B38M; JNJ-68284528 Approved Nanjing Legend Biotechnology Co Ltd Carvykti, 卡卫荻 United States Multiple Myeloma Nanjing Legend Biotechnology Co Ltd, Janssen Research & Development Llc 2022-02-28 Multiple Myeloma Details
Elranatamab PF-06863135; PF‑3135; RN-613 Approved Pfizer Inc Elrexfio, ELREXFIO, ELREXFIO™ United States Multiple Myeloma Pfizer Inc 2023-08-14 Bone Marrow Neoplasms; Smoldering Multiple Myeloma; Immunoglobulin Light-chain Amyloidosis; Multiple Myeloma Details

임상 약품 정보

Name Research Code Research Phase Company Indications Clinical Trials
Autologous BCMA-directed CAR T-cell therapy (The First Affiliated Hospital of Soochow University) Phase 3 Clinical The First Affiliated Hospital Of Soochow University Leukemia; Multiple Myeloma Details
Anitocabtagene autoleucel CART-ddBCMA; Kite-772 Phase 3 Clinical Arcellx Inc Myasthenia Gravis; Neuromuscular Manifestations; Autoimmune Diseases; Multiple Myeloma; Muscular Diseases; Muscle Weakness; Autoimmune Diseases of the Nervous System Details
CD3 and B-cell maturation antigen T-cell engaging bispecific antibody (AbbVie/TeneoOne) ABBV-383; TNB-383B Phase 3 Clinical TeneoOne Inc Immunoglobulin Light-chain Amyloidosis; Multiple Myeloma Details
Anti-BCMA chimeric antigen receptor T cell therapy (Cartesian) Descartes-08 Phase 3 Clinical Cartesian Therapeutics Inc Myasthenia Gravis; Multiple Myeloma; Lupus Erythematosus, Systemic Details
BCMA CAR-T Cells (Pregene) PRG-1801; GLPG-5301; DRL-1801 Phase 2 Clinical Purpura, Thrombocytopenic, Idiopathic; Immunoglobulin G4-Related Disease; Multiple Myeloma; Lupus Nephritis Details
Anti BCMA CAR T cell therapy (Shanghai Hrain Biotechnology) BCMA-CART; HR003 Phase 2 Clinical Hrain Biotechnology Co Ltd Multiple Myeloma Details
Anti BCMA chimeric antigen receptor T cell therapy (Chongqing Precision Biotech) Phase 2 Clinical Chongqing Precision Biotechnology Co Ltd Lymphoma, B-Cell; Multiple Myeloma; Lymphoma, Non-Hodgkin Details
BCMA CAR-T cell therapy (Chongqing Precision Biotech) Phase 2 Clinical Chongqing Precision Biotechnology Co Ltd Plasmacytoma; Multiple Myeloma; Neoplasms, Plasma Cell Details
C-CAR088 C-CAR088 Phase 2 Clinical Cellular Biomedicine (Shanghai) Co Ltd Multiple Myeloma Details
Orvacabtagene autoleucel ET-140; FCARH-143; ET140-CAR; MCARH-171; JCARH-125 Phase 2 Clinical Juno Therapeutics Inc, Memorial Sloan Kettering Cancer Center, Eureka Therapeutics Inc Multiple Myeloma Details
GC-012F GC-012F; GC012F; AZD-0120; AZD0120 Phase 2 Clinical Gracell Biotechnologies (Shanghai) Co Ltd Myasthenia Gravis; Multiple Myeloma; Lupus Erythematosus, Systemic; Lymphoma, Non-Hodgkin Details
BCMA-PD1 CAR T cell therapy (General Hospital of the People's Liberation Army) Phase 2 Clinical People'S Liberation Army General Hospital Military Service Multiple Myeloma Details
KQ-2003 KQ2003; KQ-2003 Phase 2 Clinical Shanghai Keqi Pharmaceutical Technology Co Ltd Solid tumours; Multiple Myeloma; POEMS Syndrome Details
HDP-101 HDP-101; HDP101-ATAC Phase 2 Clinical Heidelberg Hematologic Diseases; Paraproteinemias; Multiple Myeloma Details
REGN-5459 REGN-5459 Phase 2 Clinical Regeneron Pharmaceuticals Inc Multiple Myeloma; Renal Insufficiency, Chronic Details
BCMA/CD19 chimeric antigen receptor (CAR)-modified T cells Therapy(Peking University People's Hospital) Phase 2 Clinical Peking University People'S Hospital Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Myositis; Immunoglobulin G4-Related Disease; Sjogren's Syndrome; Scleroderma, Systemic; Antiphospholipid Syndrome; Lupus Erythematosus, Systemic; Acquired thrombotic thrombocytopenic purpura; Behcet Syndrome Details
anti-BCMA/FcRL5 CAR T cell therapy (Xuzhou Medical University) Phase 2 Clinical Xuzhou Medical University (Xzmu) Multiple Myeloma Details
BCMA-GPRC5D CAR-T cells Therapy (Shenzhen University General Hospital) Phase 2 Clinical Shenzhen University General Hospital Multiple Myeloma Details
Chimeric Antigen Receptor Modified T Cells Targeting BCMA(The First Affiliated Hospital of Xiamen University) Phase 2 Clinical The First Affiliated Hospital Of Xiamen University Hematologic Neoplasms; Multiple Myeloma Details
BCD-248 BCD-248 Phase 2 Clinical BIOCAD JSC Multiple Myeloma Details
Nanobody-based biepitope BCMA-targeting CAR-T cells therapy(Tahoe Chunyu Biotechnology) Phase 2 Clinical Hebei Tahoe Chunyu Biotechnology Co Ltd Multiple Myeloma Details
CAR-T Cell Therapy(Shenzhen Geno-Immune Medical Institute) Phase 2 Clinical Shenzhen Geno-Immune Medical Institute, The No.2 Clinical Hospital of the Ministry of Health Plasmacytoma; Multiple Myeloma Details
Fourth-gen CAR T Cells Targeting BCMA/CD19 therapy(Essen Biotech) Phase 2 Clinical Essen Biotech Granulomatosis with Polyangiitis; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Microscopic Polyangiitis; Myositis; Scleroderma, Systemic; Autoimmune Diseases; Sjogren's Syndrome; Lupus Nephritis; Lupus Erythematosus, Systemic Details
Anti-BCMA CAR-NK Therapy(Shahid Beheshti University of Medical Sciences) Phase 2 Clinical Shahid Beheshti University Of Medical Sciences Multiple Myeloma Details
IBI-3003 IBI3003; IBI-3003 Phase 2 Clinical Innovent Biologics(Suzhou) Co Ltd Multiple Myeloma Details
BCMA-GPRC5D CAR-T Cells Therapy (Bio-Gene) Phase 2 Clinical Guangzhou Bio-Gene Technology Co Ltd Multiple Myeloma Details
CART-ASCT-CART2 cells Therapy(Institute Of Hematology & Blood Diseases Hospital) Phase 2 Clinical Institute Of Hematology & Blood Diseases Hospital Multiple Myeloma Details
MBS-314 MBS-314 Phase 2 Clinical Beijing Mabworks Biotech Co Ltd Multiple Myeloma Details
SAR445514 SAR445514; SAR-445514; IPH6401/SAR514 Phase 2 Clinical Sanofi Immunoglobulin Light-chain Amyloidosis; Multiple Myeloma Details
CART-BCMA(Simnova) SNC-102(Simnova); SNC102(Simnova) Phase 2 Clinical Shanghai Simnova Biotechnology Co Ltd Multiple Myeloma Details
Autologous anti-BCMA/GPRC5D CAR-T cell therapy (Shanghai YaKe Biotechnology) Phase 2 Clinical Shanghai YaKe Biotechnology Co Ltd Multiple Myeloma Details
CAR-BCMA(Sheba Medical Center) Phase 2 Clinical Sheba Medical Center, Israel Multiple Myeloma Details
Humanized CART Directed Against BCMA ARI-0002h Phase 2 Clinical Instituto De Salud Carlos Iii Multiple Myeloma Details
Descartes-11 Descartes-11; Descartes-011 Phase 2 Clinical Cartesian Therapeutics Inc Multiple Myeloma Details
BCMA CAR-T Cell Therapy (Shenzhen University General Hospital) Phase 2 Clinical Shenzhen University General Hospital Multiple Myeloma Details
GR-1803 GR-1803 Phase 2 Clinical Chongqing Zhixiang Jintai Biopharmaceutical Co Ltd, Genrix (Shanghai) Biopharmaceutical Co Ltd Multiple Myeloma Details
CM-336(Connaught Biomedical Technology) CM-336; OM336 Phase 2 Clinical Keymed Biosciences Co Ltd Multiple Myeloma Details
PHE-885 PHE-885 Phase 2 Clinical Novartis Pharma Ag Hematologic Neoplasms; Multiple Myeloma Details
EMB-06 EMB-06; EMB06; CN106; CND106; CND-106 Phase 2 Clinical Shanghai Epimab Biotherapeutics, Inc Multiple Myeloma; Pemphigus Details
NXC-201 HBI-0101; NXC-201 Phase 2 Clinical Immix Biopharma Inc, Hadassah Medical Organization Immunoglobulin Light-chain Amyloidosis; Multiple Myeloma Details
BCMA Targeted CAR-T Cell Therapy (Yake Biotechnology) Phase 2 Clinical Shanghai YaKe Biotechnology Co Ltd Neoplasms; Multiple Myeloma Details
BCMA TriTAC HPN-217 Phase 1 Clinical Harpoon Therapeutics, Abbvie Inc Multiple Myeloma Details
ACTR 087/SEA BCMA combination therapy Phase 1 Clinical Unum Therapeutics Inc Multiple Myeloma Details
bb-21217 bb-21217 Phase 1 Clinical Bluebird Bio Inc, Bristol-Myers Squibb Company Multiple Myeloma Details
AMG-224 AMG-224 Phase 1 Clinical Amgen Inc Multiple Myeloma Details
Ispectamab debotansine CC-99712; BMS-986352; SP-8919 Phase 1 Clinical Celgene Corp Multiple Myeloma Details
Pacanalotamab AMG-420; BI-836909 Phase 1 Clinical Micromet Inc Multiple Myeloma Details
ALLO-715 ALLO-715 Phase 1 Clinical Cellectis Sa Multiple Myeloma Details
Alnuctamab CC-93269; EM-901; BMS-986349 Phase 1 Clinical Engmab Ag Multiple Myeloma Details
Pavurutamab AMG-701 Phase 1 Clinical Amgen Inc Multiple Myeloma Details
CART-BCMA MTV-273; CART-BCMA Phase 1 Clinical University Of Pennsylvania Rejection of renal transplantation; Renal Insufficiency; Multiple Myeloma; Kidney Failure, Chronic Details
BCMA-CD19 cCAR T cell therapy (iCell Gene Therapeutics) Phase 1 Clinical Icell Gene Therapeutics (Int'L) Ltd Multiple Myeloma; Lupus Erythematosus, Systemic; Pancytopenia; Waldenstrom Macroglobulinemia Details
Anti-BCMA anti-CD38 bispecific chimeric antigen receptor T cell therapy (Shengyan Pharmaceutical Technology) Phase 1 Clinical Shengyan Pharmaceutical Technology Multiple Myeloma Details
Descartes-15 Descartes-015; Descartes-15 Phase 1 Clinical Cartesian Therapeutics Inc Solid tumours; Multiple Myeloma; Autoimmune Diseases of the Nervous System Details
ACLX-001 ACLX-001 Phase 1 Clinical Arcellx Inc Multiple Myeloma Details
CB-011 CB-011 Phase 1 Clinical Caribou Biosciences Inc Multiple Myeloma Details
FT-576 FT-576 Phase 1 Clinical University Of Minnesota, Fate Therapeutics Inc Bone Marrow Neoplasms; Multiple Myeloma Details
P-BCMA-ALLO1 P-BCMA-ALLO1; RG-6538 Phase 1 Clinical Janssen Biotech Inc, Transposagen Biopharmaceuticals Inc Multiple Myeloma Details
Anti-CD19/BCMA CAR NK cells therapy(The Children's Hospital of Zhejiang University School of Medicine) KN5601; KN-5601 Phase 1 Clinical The Children'S Hospital, Zhejiang University School Of Medicine Nephrosis; Autoimmune Diseases; Lupus Erythematosus, Systemic Details
RD06-05 CART Cell Therapy(Nanjing Bioheng Biotech) RD06-05 Phase 1 Clinical Nanjing Bioheng Biotech Co Ltd Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Scleroderma, Systemic; Multiple Sclerosis; Neuromyelitis Optica; Lupus Erythematosus, Systemic Details
Universal allogeneic anti-CD19/BCMA CAR T-cells therapy(XiNiao Biotechnology) Phase 1 Clinical Hangzhou XiNiao Biotechnology Co Ltd Anemia, Hemolytic, Autoimmune Details
68Ga-BC1 68Ga-BC1 Phase 1 Clinical The First Affiliated Hospital Of Beijing University Multiple Myeloma; Neoplasms, Plasma Cell Details
ESO-T01 ESO-T01 Phase 1 Clinical Shenzhen Pregene Biopharma Co Ltd Multiple Myeloma Details
Universal BCMA-Targeted CAR-T Therapy(Wondercel) REVO-UWD-00B Phase 1 Clinical Wondercel Therapeutics Co Ltd Multiple Myeloma Details
Anti-BCMA/CD70 CAR-T cells therapy(The Children'S Hospital, Zhejiang University School Of Medicine) Phase 1 Clinical The Children'S Hospital, Zhejiang University School Of Medicine Nephrosis Details
PRG-2311 PRG-2311 Phase 1 Clinical Immunoglobulin G4-Related Disease; Lupus Nephritis Details
BZE-2204 BZE2204; BZE-2204 Phase 1 Clinical Shanghai Cell Therapy Group Co Ltd Lymphoma, B-Cell; Multiple Myeloma Details
OL-101 OL-101 Phase 1 Clinical Overland Pharmaceuticals (Shanghai) Co Ltd Multiple Myeloma Details
Anti-CD19/BCMA CAR T-cell therapy(YaKe Biotechnology) Phase 1 Clinical Shanghai YaKe Biotechnology Co Ltd, Zhejiang University Lupus Nephritis; Lupus Erythematosus, Systemic Details
Zirconium-89 belantamab 89Zr-GSK2857914 Phase 1 Clinical Glaxosmithkline Plc Neoplasms; Multiple Myeloma Details
RD-140 RD140 Phase 1 Clinical Nanjing Iaso Biotherapeutics Co Ltd Leukemia, Plasma Cell; Multiple Myeloma Details
BCMA CAR-NK (Hrain Biotechnology) HR012 Phase 1 Clinical Hrain Biotechnology Co Ltd Leukemia, Plasma Cell; Multiple Myeloma Details
CD19/BCMA Hi-TCR-T cell therapy(Wuhan Union Hospital) Phase 1 Clinical Wuhan Union Hospital Lupus Erythematosus, Systemic Details
SYS-6020 SYS6020; SYS-6020 Phase 1 Clinical CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co Ltd Myasthenia Gravis; Multiple Myeloma; Lupus Erythematosus, Systemic Details
The autologous dual target BCMA/CD19-CAR-T cell therapy(Nanjing University School Of Medicine) FKC-288; FKC288 Phase 1 Clinical Nanjing University School Of Medicine Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Immunoglobulin G4-Related Disease; Lupus Nephritis Details
YKST-02 YKST02; YKST-02 Phase 1 Clinical Excyte Biopharma Ltd Multiple Myeloma Details
C-CAR168 CAR T-cell therapy (AbelZeta) C-CAR168 Phase 1 Clinical Cellular Biomedicine (Shanghai) Co Ltd Myasthenia Gravis; Multiple Sclerosis, Relapsing-Remitting; Autoimmune Diseases; Lupus Erythematosus, Systemic; Neuromyelitis Optica; Muscular Diseases Details
BCMAxGPRC5D CAR-T therapy (Juno Therapeutics) BMS-986453 Phase 1 Clinical Juno Therapeutics Inc Multiple Myeloma Details
SIM-0500 SIM0500; SIM-0500 Phase 1 Clinical Simcere Pharmaceutical Group Ltd Bone Marrow Neoplasms; Multiple Myeloma Details
Recombinant anti BCMA/CD3 bispecific antibody(Hualan Genetic Engineering) Phase 1 Clinical Hualan Genetic Engineering (Henan) Co Ltd Multiple Myeloma Details
BCMA Targeted CAR-T Cell Therapy (Carbiogene Therapeutics) CBG-002 CAR-T Phase 1 Clinical Carbiogene Therapeutics Co Ltd Multiple Myeloma Details
BCMA-CD19 CAR T cell therapy (Hunan Siweikang Pharma) SWK001; SWK-001 Phase 1 Clinical Hunan Siweikang Pharmaceutical Co Ltd Multiple Myeloma Details
Anti-BCMA CAR T (Nanjing Kati Medical Technology) Phase 1 Clinical Nanjing Kati Medical Technology Co Ltd Multiple Myeloma Details
Belantamab GSK2857914; GSK-2857914 Phase 1 Clinical Glaxosmithkline Plc Multiple Myeloma; Lupus Erythematosus, Systemic Details
Anti-BCMA CAR T-cell therapy (Actavis/Eugia Pharma) Phase 1 Clinical Eugia Pharma Specialities Ltd, Actavis Inc Multiple Myeloma Details
LUCAR-B68 cells Therapy(Nanjing Legend Biotech Co) Phase 1 Clinical Nanjing Legend Biotechnology Co Ltd Multiple Myeloma Details
Universal BCMA-CD19 CART cell therapy(BRL Medicine) BRL-302 Phase 1 Clinical BRL Medicine Inc Myasthenia Gravis; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Solid tumours; Autoimmune Diseases; Multiple Sclerosis; Lupus Nephritis; Neuromyelitis Optica; Prostatic Neoplasms Details
TQB-2934 TQB2934; TQB-2934 Phase 1 Clinical Nanjing Shunxin Pharmaceuticals Co Ltd Of Chiatai Tianqing Pharmaceutical Group Multiple Myeloma Details
MCARH-125 MCARH-125 Phase 1 Clinical Memorial Sloan Kettering Cancer Center Multiple Myeloma Details
ISB-2001 ISB-2001 Phase 1 Clinical Ichnos Sciences Sa Multiple Myeloma Details
OriC-321 OriC-321; Ori-C-321 Phase 1 Clinical Zhejiang University, OriCell Therapeutics Co Ltd Multiple Myeloma Details
HY-027 HY-027 Phase 1 Clinical Juventas Cell Therapy Ltd Multiple Myeloma Details
MEDI-2228 MEDI-2228 Phase 1 Clinical Medimmune Llc Multiple Myeloma Details
IBI-346 IBI-346 Phase 1 Clinical Innovent Biologics(Suzhou) Co Ltd Multiple Myeloma Details
BCMA-NKE BCMA-NKE Phase 1 Clinical Bristol-Myers Squibb Company Multiple Myeloma Details
MCM-998 MCM-998; LXG-250 Phase 1 Clinical Novartis Pharma Ag Multiple Myeloma Details
BCMA-UCART cell therapy (Shanghai Bioray Laboratory) Phase 1 Clinical BRL Medicine Inc Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Myasthenia Gravis; Multiple Sclerosis; Multiple Myeloma; Neuromyelitis Optica Details
ALLO-605 ALLO-605; ALLO605 Phase 1 Clinical Cellectis Sa, Overland Pharmaceuticals (Shanghai) Co Ltd Multiple Myeloma Details
AUTO-8 AUTO-8; AUTO8 Phase 1 Clinical Autolus Therapeutics Plc, University College London Multiple Myeloma Details
Recombinant humanized anti-BCMA/CD3 bispecific antibody(New Time Pharmaceutical) Phase 1 Clinical Shandong New Time Pharmaceutical Co Ltd Multiple Myeloma Details
CXCR4 modified anti-BCMA CAR T cell therapy (Sichuan University) Phase 1 Clinical Sichuan University Multiple Myeloma Details
JWCAR129 JWCAR129; JWCAR-129 Phase 1 Clinical Suzhou Yaomingjunuo Biotechnology Co Ltd Multiple Myeloma Details
Anti-BCMA CAR-T cell therapy (Xinqiao Hospital) Phase 1 Clinical Chongqing Xinqiao Hospital Multiple Myeloma Details
BCMA-targeted universal LCAR-BCX cell therapy (Nanjing Legend Biotech) LCAR-BCX Phase 1 Clinical Nanjing Legend Biotechnology Co Ltd Multiple Myeloma Details
CD19/BCMA-targeted CAR-T Cell Therapy (Zhejiang University) Phase 1 Clinical Zhejiang University, Shanghai YaKe Biotechnology Co Ltd Nephritis; Scleroderma, Systemic; Autoimmune Diseases; Sjogren's Syndrome; Multiple Myeloma; Lupus Nephritis; Lupus Erythematosus, Systemic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, Non-Hodgkin Details
C-4-29 Phase 1 Clinical Chongqing Precision Biotechnology Co Ltd Carcinoma, Renal Cell; Multiple Myeloma Details
Anti-BCMA CAR-T cell therapy (PersonGen Biomedicine) Phase 1 Clinical Persongen Biotherapeutics Multiple Myeloma Details
BCMA CAR-T cell therapy (Hebei Senlang Biotechnology) Phase 1 Clinical Hebei Senlang Biological Technology Co Ltd Multiple Myeloma Details
CC-98633 CC-98633 Phase 1 Clinical Celgene Corp Multiple Myeloma Details
Anti-BCMA CAR T cell therapy (Wuhan Bio-Raid Biotechnology) Clinical Wuhan BioRaid Biotechnology Co Ltd Hematologic Neoplasms Details
Anti-BCMA CAR T-cell therapy (Huazhong University of Science and Technology) Clinical Huazhong University Of Science And Technology Multiple Myeloma Details
SA-102 SA-102; SA102 Clinical Wuhan Si'an Medical Technology Co Ltd Multiple Myeloma Details
Allogeneic Anti-BCMA/GPRC5D Bispecific CAR-NK Cells therapy(Acellytron Therapeutics) ACT-001(Acellytron Therapeutics) Clinical Acellytron Therapeutics Multiple Myeloma Details
Anti-BCMA chimeric antigen receptor natural killer cell therapy (Hangzhou Cheetah Cell Therapeutics) Clinical Multiple Myeloma Details
PD-1Ab21-BCMACAR-T (CD biopharma) CD-003; CD-203 Clinical Multiple Myeloma Details
BCMA targeting UCAR-T cell therapy (PersonGen BioTherapeutics) UTAA17 Clinical Persongen Biotherapeutics (Suzhou) Co Ltd Multiple Myeloma Details
CT-0590(The First Affiliated Hospital Of Soochow University) CT-0590 Clinical CARsgen Therapeutics Holdings Ltd Multiple Myeloma Details
UF-KURE-BCMA CAR-T Cells therapy(University Hospitals Cleveland Medical Center) University Hospitals Cleveland Medical Center Details

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