로그인 회원가입
icon_bulk_order대량 주문 Acrobiosystems for English
Promotion
Recombinant Proteins ClearClear history
Recombinant Proteins CloseClose
Browse Products By Molecule Name a-zA-Z
TL1A Hot |GMP IL-2 Hot |FcRn Binding Kit (TR-FRET) New |Claudin 18.2 Hot
0
장바구니가 비어 있습니다
내 장바구니
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: 홈 > CD133

CD133

요약

Name:CD133
Target Synonym:Antigen AC133,Prominin-1,PROM1,Prominin 1,Prominin-Like Protein 1,PROML1,Stargardt Disease 4 (Autosomal Dominant),Hematopoietic Stem Cell Antigen,Macular Dystrophy, Retinal 2,Prominin (Mouse)-Like 1,CD133 Antigen,HProminin,MSTP061,CORD12,AC133,CD133,MCDR2,STGD4,RP41,AC133 Antigen
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

제품 리스트 구매

제품> 결과 필터링
제품 상태별:
제품 유형별 :
종별:
태그별:
결합물별:
제품번호 종 제품 설명 구조 순도 특징
CD3-H82D3 Human Biotinylated Human CD133 Full Length Protein, His,Flag Tag&Avitag™ (Detergent)
CD3-H82D3-structure
CD3-H82D3-sds
CD3-C82E3 Cynomolgus Biotinylated Cynomolgus CD133 Full Length Protein, His,Avitag™ (Detergent)
CD3-C82E3-structure
CD3-H52P3 Human Human CD133 Full Length Protein (VLP)
CD3-H52H1 Human Human CD133 Full Length Protein, His Tag (Nanodisc)
CD3-H52H1-structure
CD3-H52H1-sds
CD3-H52H4 Human Human CD133 Protein, His Tag (Detergent)
CD3-H52H4-structure
CD3-H52H4-sds

일부의 생물활성 데이터

CD3-H52H1-Cell-based assay
CD133 FACS

2e5 of Anti-CD133 CAR-293 cells were stained with 100 μL of 3 μg/mL of Human CD133 Full Length Protein, His Tag (Cat. No. CD3-H52H1) and negative control protein respectively, washed and then followed by PE-anti-His Tag antibody and analyzed with FACS (QC tested).

Protocol
CD3-H82D3-SPR
CD133 SPR

Monoclonal Anti-Human CD133 Antibody captured on Protein A Chip can bind Biotinylated Human CD133 Full Length Protein, His,Flag Tag&Avitag (Cat. No. CD3-H82D3) with an affinity constant of 27.1 nM as determined in a SPR assay (in presence of DDM and CHS) (Biacore 8K) (Routinely tested).

Protocol
CD3-C82E3-ELISA
CD133 ELISA

Immobilized Biotinylated Cynomolgus CD133 Full Length Protein, His,Avitag (Cat. No. CD3-C82E3) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Monoclonal Anti-Human CD133 Antibody, Human IgG1 with a linear range of 0.06-2 ng/mL (QC tested).

Protocol

Synonym Name

CD133,PROM1,PROML1,Prominin-1,AC133

Background

Prominin-1 is also known as CD133, Antigen AC133, PROM1, PROML1 and MSTP061. Is used as marker for hematopoietic stem and progenitor cells (HSPC) for somatic stem cell isolation. May play a role in cell differentiation, proliferation and apoptosis . Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

Clinical and Translational Updates

임상 약품 정보

Name Research Code Research Phase Company Indications Clinical Trials
anti-CD133-CAR vector-transduced T cells Phase 2 Clinical Pla General Hospital Ovarian Neoplasms; Liver Neoplasms; Pancreatic Neoplasms; Brain Neoplasms; Breast Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Colorectal Neoplasms Details

This web search service is supported by Google Inc.

totop
Call us
전화
글로벌: +1 800-810-0816 (무료)
아시아태평양: +86 400-682-2521
Email
이메일
order.kr@acrobiosystems.com
Address
주소
서울 성동구 왕십리로10길 6 서울숲비즈포레 703
회사명
아크로바이오 주식회사
linkedin twitter facebook youtube

문의

Copyright © 2017 ACROBiosystems. All Rights Reserved
Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap