로그인 회원가입
icon_bulk_order대량 주문 Acrobiosystems for English
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: > TNF-alpha

TNF-alpha

요약

Name:Tumor necrosis factor α
Target Synonym:ICD1,Tumor necrosis factor,Tumor Necrosis Factor (TNF Superfamily, Member 2),Tumor Necrosis Factor Ligand 1F,Tumor Necrosis Factor-Alpha,TNF Superfamily, Member 2,TNF, Macrophage-Derived,TNF, Monocyte-Derived,APC1 Protein,TNLG1F,DIF,NTF,TNF-a,TNF-alpha,ICD2,N-terminal fragment,TNF,Tumor necrosis factor ligand superfamily member 2,Cachectin,TNFSF2,TNFA
Number of Launched Drugs:51
Number of Drugs in Clinical Trials:65
Lastest Research Phase:Approved

제품 리스트 비교 또는 구매

제품번호 제품 설명 구조 순도 특징
EP-147 Human TNF-alpha [Biotinylated] : TNFR2 Inhibitor Screening ELISA Kit
CRS-D002 Human Human Tumor Necrosis Factor Alpha (TNF-α) ELISA Assay Pair
TNA-M52H3 Mouse Mouse TNF-alpha Protein, His Tag
TNA-M52H3-structure
EP-143 Human TNF-alpha [Biotinylated] : TNFR1 Inhibitor Screening ELISA Kit
TNA-BLM494 Human Biotinylated Monoclonal Anti-TNF-alpha antibody, human IgG1 (16H5) (MALS verified)
TNA-BLM494-sds
TNA-AM493 Human Monoclonal Anti-TNF-alpha Antibody, Human IgG1 (13B8)
TNA-AM493-sds
TNA-AM494 Human Monoclonal Anti-TNF-alpha antibody, Human IgG1 (16H5)
TNA-AM494-sds
CEA-C010 Human ClinMax™ Human TNF-α ELISA Kit
TNA-Y59 Mouse Monoclonal Anti-TNF-alpha antibody, Mouse IgG1 (16H5)
TNA-Y58 Mouse Monoclonal Anti-TNF-alpha antibody, Mouse IgG1 (13B8)
CRS-A002 Human Human Tumor Necrosis Factor Alpha (TNF-α) ELISA Kit
TNA-C52H3 Canine Canine TNF-alpha Protein, His Tag, active trimer (MALS verified)
TNA-C52H3-structure
TNA-C52H3-sds
TNA-H5228 Human Human TNF-alpha Protein, His Tag (active trimer) (MALS verified)
TNA-H5228-structure
TNA-H5228-sds
TNA-M82E9 Mouse Biotinylated Mouse TNF-alpha Protein, His,Avitag™ (active trimer) (MALS verified)
TNA-M82E9-structure
TNA-M82E9-sds
TNA-H82E3 Human Biotinylated Human TNF-alpha Protein, His,Avitag™ (active trimer) (MALS verified)
TNA-H82E3-structure
TNA-H82E3-sds
TNA-H8211 Human Biotinylated Human TNF-alpha Protein, epitope tag free, ultra sensitivity (primary amine labeling) (active trimer) (MALS verified)
TNA-H8211-structure
TNA-H8211-sds
TNA-H4211 Human Human TNF-alpha Protein, premium grade
TNA-H4211-structure
TNA-H4211-sds

일부의 생물활성 데이터

TNA-H5228-Cell-based assay
Human FcRn Heterodimer Protein Cell_Base

Human TNF-alpha, His Tag (active trimer) (MALS verified) (Cat. No. TNA-H5228) induces cytotoxicity effect on the WEH1-13VAR cells in the presence of the metabolic inhibitor actinomycin D. The EC50 for this effect is 0.013-0.074 ng/mL (Routinely tested).

TNA-H5228-Cell-based assay
Human FcRn Heterodimer Protein Cell_Base

Neutralization assay shows that the cytotoxicity effect of Human TNF-alpha, His Tag (active trimer) (MALS verified) (Cat. No. TNA-H5228) was inhibited by increasing concentration of Adalimumab. The concentration of TNF-alpha used is 1 ng/mL. The IC50 is 26.8 ng/mL (Routinely tested).

TNA-BLM494-SPR
 TNF-alpha SPR

Biotinylated Monoclonal Anti-TNF-alpha antibody, human IgG1 (16H5) (Cat. No. TNA-BLM494) captured on CM5 chip via Anti-human IgG Fc antibodies surface can bind Human TNF-alpha, His Tag (active trimer) (MALS verified) (Cat. No. TNA-H5228) with an affinity constant of 75.9 pM as determined in a SPR assay (Biacore 8K) (Routinely  tested).

TNA-AM493-SPR
 TNF-alpha SPR

Monoclonal Anti-TNF-alpha antibody, Human IgG1 (13B8) (Cat. No. TNA-AM493) captured on CM5 chip via Anti-human IgG Fc antibodies surface can bind Human TNF-alpha, His Tag (Cat. No. TNA-H5228) with an affinity constant of 0.133 nM as determined in a SPR assay (Biacore 8K) (Routly tested).

Synonym Name

DIF,TNF-alpha,TNFA,TNFSF2,cachexin,cachectin,TNFα

Background

Tumor necrosis factor alpha (TNFα)  is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFα is in the regulation of immune cells. TNFα is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFα production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNFα is used as an immunostimulant under the INN tasonermin. TNFα can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.

Clinical and Translational Updates

공개 약품 정보

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Etanercept biosimilar (Hisun-Pfizer Pharmaceuticals) Approved Hisun-Pfizer AnBaiNuo Mainland China Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis Wyeth Europa Ltd 2010-02-26 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic Details
Infliximab biosimilar (Bionovis/The Instituto Vital Brazil) Approved Bionovis, The Instituto Vital Brazil Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease Details
Etanercept biosimilar (Intas Biopharmaceuticals) Approved Intas Biopharmaceuticals Intacept India Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Psoriasis Intas Biopharmaceuticals 2015-03-01 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic Details
Anti-tumour necrosis factor-alpha antibody Approved Materia Medica Holding Research And Production Company Artrofoon, Arthrofoon Arthritis, Rheumatoid; Osteoarthritis Details
Etanercept biosimilar (AryoGen Biopharma) Approved Aryogen Biopharma Altebrel Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic Details
Etanercept biosimilar (Nanogen Biopharmaceutical) Approved Nanogen Biopharmaceutical Co Nanercept Vietnam Psoriasis; Arthritis, Rheumatoid Nanogen Biopharmaceutical Co 2019-01-01 Arthritis, Rheumatoid; Psoriasis Details
Etanercept biosimilar (PROBIOMED) Approved Probiomed Infinitam Mexico Arthritis, Rheumatoid Probiomed 2014-01-01 Arthritis, Rheumatoid Details
Adalimumab biosimilar (Reliance Life Sciences) R-TPR-021 Approved Reliance Life Sciences Adfrar IB India Colitis, Ulcerative; Psoriasis; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Psoriatic Reliance Life Sciences, Torrent Pharma 2016-01-12 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic Details
Infliximab biosimilar (AXXO) Approved Axxo Russian Federation Crohn Disease; Autoimmune Diseases Axxo 2013-01-01 Autoimmune Diseases; Crohn Disease Details
Etanercept biosimilar (Mochida) LBEC-0101 Approved Mochida Pharmaceutical Co Ltd Japan Arthritis, Juvenile; Arthritis, Rheumatoid null 2018-01-19 Arthritis, Rheumatoid; Arthritis, Juvenile Details
Etanercept biosimilar (Amega Biotech) Approved Amega Biotech Enerceptan Argentina Arthritis, Rheumatoid Amega Biotech 2012-01-01 Arthritis, Rheumatoid Details
Etanercept biosimilar (Mylan) YLB-113 Approved Rubin Ltd, Mylan Nv Nepexto EU Arthritis, Rheumatoid; Spondylarthropathies; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Plaque psoriasis Mylan Ire Healthcare Ltd 2020-05-20 Arthritis, Rheumatoid; Spondylarthropathies; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Psoriatic; Plaque psoriasis Details
Recombinant human type II tumor necrosis factor receptor-antibody fusion protein(Shanghai Cp Guojian) Approved Shanghai Cp Guojian Pharmaceutical Co Ltd 益赛普 Spondylitis, Ankylosing; Arthritis, Rheumatoid Details
Adalimumab biosimilar (CTTQ Pharma) Approved Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd Mainland China Spondylitis, Ankylosing; Arthritis, Rheumatoid Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd 2022-01-18 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease Details
Adalimumab biosimilar (Jiangsu Zhonghe/Shanghai Junshi/Jiangsu T-Mab) UBP-1211; 9MW0113; 9-MW-0113; 9-MW0113; 9MW-0113 Approved Shanghai Junshi Biosciences Co Ltd, Jiangsu Zhonghe Pharmaceutical Technology Co Ltd, Jiangsu T-Mab Bio-Pharmaceuticals Co Ltd, Mabwell (Shanghai) Bioscience Co Ltd Mainland China Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis Shanghai Junshi Biosciences Co Ltd 2022-03-01 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis Details
Infliximab biosimilar (Pfizer) PF-6438179; GP-1111; PF-06438179 Approved Pfizer Inc Ixifi, Zessly Japan Colitis, Ulcerative; Crohn Disease; Psoriasis; Arthritis, Rheumatoid; Arthritis, Psoriatic Pfizer Inc 2013-09-09 Pediatric Crohn's disease; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Pediatric ulcerative colitis; Colitis, Ulcerative; Arthritis, Psoriatic; Crohn Disease Details
Infliximab biosimilar (Shanghai Biomabs) CMAB-008; STI-002 Approved Shanghai Biomabs Pharmaceuticals Co Ltd 百类停, 类停 Mainland China Psoriasis; Arthritis, Rheumatoid; Pediatric Crohn's disease; Crohn Disease; Spondylitis, Ankylosing; Colitis, Ulcerative Taizhou Mabtech Pharmaceutical Co Ltd 2021-07-12 Arthritis, Rheumatoid; Pediatric Crohn's disease; Spondylitis, Ankylosing; Psoriasis; Colitis, Ulcerative; Crohn Disease Details
Adalimumab biosimilar (Zydus Cadila) ZRC-3197 Approved Zydus Cadila Exemptia, Adaly India Arthritis, Juvenile; Arthritis, Rheumatoid; Arthritis, Psoriatic; Spondylitis, Ankylosing Zydus Cadila 2014-12-09 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Psoriatic Details
Adalimumab biosimilar (Hisun Pharma) HS-016 Approved Zhejiang Hisun Pharmaceutical Co Ltd 安健宁 Mainland China Spondylitis, Ankylosing; Arthritis, Rheumatoid Hisun Biopharmaceutical Co Ltd 2019-12-06 Spondylitis, Ankylosing; Arthritis, Rheumatoid Details
Infliximab biosimilar (Hisun Pharma) HS-626 Approved Zhejiang Hisun Pharmaceutical Co Ltd Mainland China Psoriasis Hisun Biopharmaceutical Co Ltd 2021-09-24 Psoriasis Details
Etanercept biosimilar (Samsung Bioepis) SB-4 Approved Samsung Bioepis Eticovo, Benepali United States Arthritis, Juvenile; Arthritis, Rheumatoid; Psoriasis; Spondylitis, Ankylosing; Arthritis, Psoriatic Samsung Bioepis Co Ltd 2016-01-13 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic Details
Adalimumab biosimilar (Pfizer) PF-06410293 Approved Pfizer Pharmaceuticals Ltd (China) Amsparity, Abrilada, Fyzoclad EU Crohn Disease; Uveitis; Psoriasis; Hidradenitis Suppurativa; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Colitis, Ulcerative Pfizer Europe Ma Eeig 2019-11-15 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic; Uveitis; Hidradenitis Suppurativa; Crohn Disease Details
Infliximab biosimilar (Nichiiko/Aprogen) NI-071; GS-071; GS-07; AP-07 Approved Nichi-Iko Pharmaceutical, Aprogen Japan Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis Nichi-Iko Pharmaceutical Co Ltd 2017-09-27 Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease Details
Adalimumab biosimilar (Coherus BioSciences) CHS-1420 Approved Coherus Biosciences Inc Yusimry United States Colitis, Ulcerative; Plaque psoriasis; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Crohn Disease Coherus Biosciences Inc 2021-12-17 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic; Plaque psoriasis; Crohn Disease Details
Infliximab biosimilar (Merck & Co/Samsung Bioepis) SB-2 Approved Samsung Bioepis, Merck & Co Inc Renflexis, Flixabi United States Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Crohn Disease; Colitis, Ulcerative Samsung Bioepis Co Ltd 2016-05-26 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease Details
Opinercept E-11; ENIA-11 Approved Tsh Biopharm, Mycenax Biotech Inc TuNEX Taiwan Arthritis, Rheumatoid null 2017-01-01 Arthritis, Rheumatoid Details
Infliximab biosimilar (Celltrion) CT-P13 Approved Celltrion Remsima, Inflectra, Inflectra/Remsima, Flammegis Japan Arthritis, Psoriatic; Arthritis, Rheumatoid; Psoriasis; Colitis, Ulcerative; Crohn Disease Celltrion 2013-09-10 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Urologic Neoplasms; Crohn Disease Details
PG-201 PG-201 Approved Viromed Layla South Korea Osteoarthritis Pmg Pharm Co Ltd 2012-01-01 Osteoarthritis Details
Etanercept biosimilar (Shanghai CP Guojian Pharmaceutical) 301S Approved Shanghai Cp Guojian Pharmaceutical Co Ltd, Cipla Gmbh Yisaipu, Etacept, 益赛普, Etanar Mainland China Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis Shanghai Cp Guojian Pharmaceutical Co Ltd 2005-06-20 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis Details
Adalimumab biosimilar (Fujifilm Kyowa Kirin Biologics/Mylan) FKB-327 Approved Fujifilm Kyowa Kirin Biologics Co Ltd Hulio EU Hidradenitis Suppurativa; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Uveitis Viatris Ltd 2018-09-16 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Psoriatic; Colitis, Ulcerative; Hidradenitis Suppurativa; Uveitis; Crohn Disease Details
Adalimumab biosimilar (Samsung Bioepis) SB-5 Approved Samsung Bioepis Imraldi, Hadlima United States Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis Samsung Bioepis Co Ltd 2017-08-24 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Pediatric Crohn's disease; Arthritis, Juvenile; Psoriasis; Pediatric ulcerative colitis; Arthritis, Psoriatic; Colitis, Ulcerative; Hidradenitis Suppurativa; Uveitis; Crohn Disease; Plaque psoriasis Details
Adalimumab biosimilar (Shanghai Henlius Biotech) HLX-03 Approved Shanghai Henlius Biotech Co Ltd 汉达远 Mainland China Uveitis, Intermediate; Uveitis, Posterior; Panuveitis Shanghai Henlius Biotech Co Ltd 2020-12-02 Uveitis, Intermediate; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Uveitis, Posterior; Plaque psoriasis; Panuveitis Details
Adalimumab biosimilar (Biocad) BCD-057 Approved Biocad Russian Federation Psoriasis Biocad 2019-03-01 Psoriasis Details
Adalimumab biosimilar (Bio-Thera Solutions) BAT-1406 Approved Bio-Thera Solutions Ltd 格乐立 Mainland China Psoriasis; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Crohn Disease; Uveitis Bio-Thera Solutions Ltd 2019-11-04 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Uveitis; Crohn Disease Details
Adalimumab biosimilar (Innovent Biologics) IBI-303 Approved Innovent Biologics(Suzhou) Co Ltd 苏立信 Mainland China Crohn Disease; Pediatric Crohn's disease Innovent Biologics(Suzhou) Co Ltd 2020-09-02 Pediatric Crohn's disease; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Uveitis; Plaque psoriasis; Crohn Disease Details
Adalimumab biosimilar (Mylan/Biocon) BMO-2; MYL-1401-A Approved Biocon United States Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis Mylan Pharmaceuticals Inc 2020-07-06 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis Details
Luminol sodium MP-1032 Approved Selvim, Metrio Psoriasis; Immune System Diseases null 1997-01-01 Immune System Diseases; Psoriasis Details
Adalimumab biosimilar (Boehringer Ingelheim) BI-695501 Approved C.H. Boehringer Sohn Ag & Co. Kg Cyltezo United States Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis Boehringer Ingelheim Gmbh 2017-08-25 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Uveitis; Hidradenitis Suppurativa; Crohn Disease Details
Infliximab biosimilar (Amgen) ABP-710 Approved Amgen Inc Avsola United States Plaque psoriasis; Pediatric ulcerative colitis; Pediatric Crohn's disease; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease Amgen Inc 2019-12-06 Pediatric Crohn's disease; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Pediatric ulcerative colitis; Arthritis, Psoriatic; Colitis, Ulcerative; Plaque psoriasis; Crohn Disease Details
Adalimumab biosimilar (LG Life Sciences) LBAL Approved Lg Chemical Ltd, Mochida Pharmaceutical Co Ltd Japan Behcet Syndrome; Uveitis, Intermediate; Uveitis, Posterior; Panuveitis; Crohn Disease; Colitis, Ulcerative; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic; Arthritis, Juvenile Mochida Pharmaceutical Co Ltd 2021-03-23 Uveitis, Intermediate; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic; Uveitis, Posterior; Behcet Syndrome; Panuveitis; Crohn Disease Details
Adalimumab biosimilar (Celltrion) CT-P17 Approved Celltrion Yuflyma EU Crohn Disease; Uveitis; Pediatric ulcerative colitis; Pediatric Crohn's disease; Arthritis, Juvenile; Plaque psoriasis; Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Hidradenitis Suppurativa; Psoriasis; Spondylitis, Ankylosing Celltrion Healthcare Hungary Kft 2021-02-11 Arthritis, Rheumatoid; Pediatric Crohn's disease; Spondylitis, Ankylosing; Arthritis, Juvenile; Pediatric ulcerative colitis; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Uveitis; Hidradenitis Suppurativa; Crohn Disease; Plaque psoriasis Details
Infliximab biosimilar (Reliance Life Sciences) BOW-015; R-TPR-015 Approved Epirus Biopharmaceuticals Infimab Arthritis, Rheumatoid Details
Etanercept biosimial (Sandoz) GP-2015 Approved Clariant Produkte (Schweiz) Ag Erelzi EU Arthritis, Juvenile; Plaque psoriasis; Spondylitis, Ankylosing; Arthritis, Psoriatic; Arthritis, Rheumatoid Sandoz Gmbh 2016-08-30 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Plaque psoriasis Details
Adalimumab biosimilar (Amgen) ABP-501 Approved Amgen Inc Amgevita, Amjevita, Solymbic EU Amgen Europe Bv 2016-09-23 Non-radiographic axial spondyloarthritis; Polyarticular Juvenile Idiopathic Arthritis; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Hidradenitis Suppurativa; Uveitis; Crohn Disease; Plaque psoriasis Details
Infliximab Biosimilar (Genor Biopharma) GB-242 Approved Genor Biopharma Co Ltd 佳佑健 Mainland China Spondylitis, Ankylosing; Crohn Disease; Psoriasis; Colitis, Ulcerative; Arthritis, Rheumatoid Yuxi Genor Biotechnology Co Ltd 2022-02-23 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Colitis, Ulcerative; Crohn Disease Details
Etanercept biosimilar (Hanwha Chemical) HD-203; MK-8953 Approved Hanwha Chemical Davictrel Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic Details
Infliximab TA-650 Approved Janssen Global Services Llc Remicade, 类克, Avakine, CenTNF EU Psoriasis Janssen Biologics Bv 1998-08-24 Retinal Detachment; Psoriasis; Pediatric ulcerative colitis; Takayasu Arteritis; Breast Neoplasms; Vitreoretinopathy, Proliferative; Arthritis, Psoriatic; Colitis, Ulcerative; Aneurysm; Diabetic macular oedema; Parapsoriasis; Uveitis; Pulmonary Disease, Chronic Obstructive; Cachexia; Crohn Disease; Stevens-Johnson Syndrome; Behcet Syndrome; Diabetic Retinopathy; Spondylarthropathies; Inflammatory Bowel Diseases; Pancreatitis; Giant Cell Arteritis; Pediatric Crohn's disease; Bipolar Disorder; Vasculitis; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Berylliosis; Graft vs Host Disease; Fatigue; Coronavirus Disease 2019 (COVID-19); Sarcoidosis; Mucocutaneous Lymph Node Syndrome; Stroke; Polymyalgia Rheumatica; Visual Acuity Details
Thalidomide NSC-66847; NSC-527179; K-17; VP-02 Approved Celgene Corp Talizer, Thalidomide Celgene, Thalidomide Pharmion, Synovir, Thalomid, Thaled Japan Leprosy, Lepromatous Fujimoto Pharmaceutical 1982-01-01 Waldenstrom Macroglobulinemia; Sarcoma; Prostatic Neoplasms; Arachnoiditis; Cholangitis, Sclerosing; Gastrointestinal Hemorrhage; Osteosarcoma; Pancreatitis, Chronic; Retinoblastoma; Sarcoma, Ewing; Lymphoma, Mantle-Cell; Prostatitis; Colitis, Ulcerative; Colorectal Neoplasms; Neuroectodermal Tumors, Primitive; Erythema Nodosum; Leprosy, Lepromatous; Endometrial Neoplasms; Appendiceal Neoplasms; Pelvic Pain; Angiodysplasia; Glioma; Lymphoma, Non-Hodgkin; Carcinoma, Hepatocellular; Amyotrophic Lateral Sclerosis; Vascular Malformations; Crohn Disease; Precancerous Conditions; Mycobacterium avium-intracellulare Infection; Idiopathic Pulmonary Fibrosis; Leukemia; Lymphoma, B-Cell, Marginal Zone; Lymphoma, B-Cell; Liver Neoplasms; Cough; Telangiectasia, Hereditary Hemorrhagic; Mycobacterium Infections; Rhabdomyosarcoma; Arteriovenous Malformations; Inflammatory Bowel Diseases; Stomatitis, Aphthous; Gastric Antral Vascular Ectasia; Spondylitis, Ankylosing; Myelodysplastic Syndromes; HIV Infections; Coronavirus Dise Details
Golimumab CNTO-148; rTNV148B Approved Janssen Global Services Llc Simponi, Simponi aria, Simponi/Simponi aria Mainland China Arthritis, Rheumatoid; Spondylitis, Ankylosing Janssen Biologics Bv 2009-04-24 Diabetes Mellitus, Type 1; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Colitis, Ulcerative; Arthritis, Psoriatic; Asthma; Crohn Disease; Labyrinth Diseases Details
Certolizumab pegol PHA-738144; CDP-870; CZP Approved Ucb Cimzia, Cimziat Mainland China Arthritis, Rheumatoid Ucb Pharma Sa 2008-04-22 Infertility, Male; Polyarticular Juvenile Idiopathic Arthritis; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Spondylarthropathies; Spondylarthritis; Multiple Sclerosis; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Cystitis, Interstitial; Osteoarthritis, Spine; Crohn Disease; Plaque psoriasis Details
Adalimumab D2E7; ABT-D2E7; LU-200134 Approved Abbvie Inc 修美乐, Humira, Trudexa EU Psoriasis; Hidradenitis Suppurativa; Colitis, Ulcerative; Uveitis Stada Arzneimittel Ag 2002-12-31 Arthritis; Glomerulosclerosis, Focal Segmental; Arthritis, Psoriatic; Colitis, Ulcerative; Cystitis, Interstitial; Osteoarthritis, Knee; Asthma; Hidradenitis Suppurativa; Uveitis; Sciatica; Mucositis; Osteoarthritis; Nephrotic Syndrome; Crohn Disease; Diabetic Retinopathy; Choroidal Neovascularization; Plaque psoriasis; Bursitis; Psoriasis; Nephrosis, Lipoid; Dupuytren Contracture; Arthritis, Juvenile; Pediatric Crohn's disease; Spondylarthritis; Pouchitis; Sarcoidosis; Coronavirus Disease 2019 (COVID-19); Spondylitis, Ankylosing; Arthritis, Rheumatoid; Giant Cell Arteritis; Pain; Inflammatory Bowel Diseases; Pyoderma Gangrenosum Details
Etanercept TNR-001 Approved Pfizer Pharmaceuticals Ltd (China), Amgen Inc 恩利, Enbrel, Lifmior Mainland China Psoriasis; Spondylitis, Ankylosing; Arthritis, Rheumatoid C.H. Boehringer Sohn Ag & Co. Kg 1998-11-02 Hidradenitis Suppurativa; Prostatic Neoplasms; Asthma; Arthritis, Psoriatic; Lichen Planus; Alzheimer Disease; Bone Neoplasms; Arthritis; Inflammation; Fatigue Syndrome, Chronic; Myositis, Inclusion Body; Obesity; Lung Neoplasms; Plaque psoriasis; Neoplasm Metastasis; Kidney Failure, Chronic; Acute Lung Injury; Pemphigus; Vitiligo; Fanconi Anemia; HIV Infections; Diabetes Mellitus, Type 1; Bronchiolitis Obliterans; Leukemia; Lupus Erythematosus, Discoid; Chronic Urticaria; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Tinnitus; Synovitis; Graft vs Host Disease; Lupus Erythematosus, Cutaneous; Spondylarthritis; Pulmonary Fibrosis; Arthritis, Juvenile; Respiratory Distress Syndrome, Adult; Psoriasis Details
Pomalidomide IMID-4047; CDC-394; CC-4047; IMiD-1 Approved Celgene Corp Pomalyst, Imnovid, Actimid, Pomalyst/Imnovid, 安跃 Mainland China Multiple Myeloma Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd 2013-02-08 Lung Diseases, Interstitial; Neoplasm Metastasis; Anemia, Sickle Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Sarcoma, Kaposi; Lymphoma, Non-Hodgkin; Primary Myelofibrosis; Amyloidosis; Sarcoma; Prostatic Neoplasms; Lymphoma, Follicular; Central Nervous System Neoplasms; Bone Marrow Neoplasms; Pulmonary Fibrosis; Multiple Myeloma; Graft vs Host Disease; Hodgkin Disease; Lymphoma, Large B-Cell, Diffuse; Scleroderma, Systemic; Neoplasms; Lymphoma, B-Cell; Medulloblastoma; Solid tumours Details
Lenalidomide CC-5013; IMiD-3; ENMD-0997; STAR-LLD; CDC-501; IMID-5013; CDC-5013 Approved Celgene Corp Revimid (former Brand Name), 瑞复美, Revlimid, Leavdo EU Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular Celgene Europe Bv 2005-12-27 Lymphoma, T-Cell, Cutaneous; Lymphoma, Follicular; Reflex Sympathetic Dystrophy; Radiculopathy; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Histiocytosis, Langerhans-Cell; Prostatic Neoplasms; Demyelinating Diseases; Gliosarcoma; Primary Myelofibrosis; Histiocytic Sarcoma; Lymphoma, T-Cell; Lymphoma, Non-Hodgkin; Thrombocytopenia; Lymphoma; Leukemia, Myeloid, Acute; Lymphoma, Mantle-Cell; Waldenstrom Macroglobulinemia; Thyroid Neoplasms; Glioma; Leukemia, Monocytic, Acute; Lymphoma, Large-Cell, Anaplastic; Carcinoma, Squamous Cell; Epstein-Barr Virus Infections; Cachexia; Leukemia, Lymphocytic, Chronic, B-Cell; Crohn Disease; Melanoma; Complex Regional Pain Syndromes; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Mental Disorders; Neoplasms; Lymphoma, B-Cell, Marginal Zone; HIV Infections; Lymphoma, T-Cell, Peripheral; Lymphoma, B-Cell; Liver Neoplasms; Leukemia; Leukemia, Myeloid; Bone Marrow Neoplasms; Leukemia, Erythroblastic, Acute; Hematologic Diseases; Anemia; Paraproteinemias; Pain; Myelodys Details
Adalimumab biosimilar (Sandoz) GP-2017 Approved Sandoz Hefiya, Hyrimoz, Halimatoz United States Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis Sandoz Inc 2018-07-26 Non-radiographic axial spondyloarthritis; Polyarticular Juvenile Idiopathic Arthritis; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Uveitis; Hidradenitis Suppurativa; Plaque psoriasis; Crohn Disease Details
Adalimumab biosimilar (Fresenius Kabi) MSB-11022 Approved Merck Serono, Fresenius Kabi Ag Idacio, Kromeya EU Psoriasis; Hidradenitis Suppurativa; Colitis, Ulcerative; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Crohn Disease Fresenius Kabi Deutschland Gmbh 2019-04-02 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Uveitis; Hidradenitis Suppurativa; Crohn Disease Details

임상 약품 정보

Name Research Code Research Phase Company Indications Clinical Trials
Adalimumab biosimilar (CinnaGen) Phase 3 Clinical Cinnagen Arthritis, Rheumatoid Details
Recombinant human anti-TNFα monoclonal antibody (Huaota Biopharma) Phase 3 Clinical Shanghai Huaota Biopharmaceutical Co Ltd Spondylitis, Ankylosing; Psoriasis; Arthritis; Plaque psoriasis Details
Certolizumab (Intrexon) AG-014 Phase 1 Clinical Intrexon Co Inflammatory Bowel Diseases Details
XTMAB-16 XTMAB-16 Phase 1 Clinical Xentria Inc Sarcoidosis Details
Adalimumab biosimilar (AXXO) Clinical Axxo Arthritis, Rheumatoid; Arthritis, Psoriatic Details
IBPM005IX (Inbiopro Solutions) Clinical Inbiopro Solutions Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Arthritis, Psoriatic; Crohn Disease Details
Etanercept (Neurokine Pharmaceuticals) NP-1; NK-001 Clinical Pivot Pharmaceuticals Cognition Disorders Details
Anti-tumour necrosis factor alpha (Livzon) Phase 1 Clinical Livzon Pharmaceutical Group Inc Autoimmune Diseases Details
Adalimumab biosimilar (Hetero Drugs) Phase 3 Clinical Hetero Drugs Arthritis, Rheumatoid Details
Adalimumab biosimilar (Oncobiologics) ONS-3010 Phase 3 Clinical Outlook Therapeutics Psoriasis Details
Adalimumab biosimilar (Danhong Pharma) BC-002 Phase 3 Clinical Shandong Danhong Pharmaceutical Co Ltd Spondylitis, Ankylosing; Arthritis, Rheumatoid Details
Adalimumab biosimilar (Hualan Biological Engineering) Phase 3 Clinical Hualan Genetic Engineering Co Ltd Spondylitis, Ankylosing; Psoriasis; Arthritis Details
Adalimumab biosimilar (Tonghua Dongbao Pharmaceutical) Phase 3 Clinical Tonghua Dongbao Pharmaceutical Co Ltd Arthritis, Rheumatoid; Plaque psoriasis Details
Recombinant anti-TNFα monoclonal antibody (Wuhan Institute of Biological Products) Phase 3 Clinical Wuhan Institute Of Biological Products Co Ltd Plaque psoriasis Details
JNJ-63823539 JNJ-63823539 Phase 1 Clinical Janssen Global Services Llc Arthritis, Rheumatoid Details
ND-009 ND-009 Phase 1 Clinical Numab Therapeutics Ag, Tillotts Pharma Ag Inflammation Details
SAR-442970 SAR-442970 Phase 1 Clinical Sanofi Inflammation Details
Adalimumab biosimilar (Weimingdamu Biotech) Phase 1 Clinical Anhui Weiming Damu Biomedicine Co Ltd Arthritis, Rheumatoid Details
Adalimumab biosimilar(BioXpress) BX-2922; BXT-2922 Clinical Bioxpress Therapeutics Sa Spondylitis, Ankylosing; Pediatric Crohn's disease; Arthritis, Rheumatoid; Arthritis, Juvenile; Colitis, Ulcerative; Arthritis, Psoriatic; Uveitis; Hidradenitis Suppurativa; Crohn Disease Details
Adalimumab biosimillar(Huabo) Onco-3010; HOT-3010 Phase 3 Clinical Huabo Biopharm Co Ltd Arthritis, Rheumatoid Details
Infliximab biosimilar (Ospedale San Raffaele) Phase 1 Clinical Ospedale San Raffaele Takayasu Arteritis Details
Recombinant anti-TNFα monoclonal antibody (Livzon Group) AT-132; LZM-001 Phase 2 Clinical Livzon Pharmaceutical Group Inc Arthritis, Rheumatoid Details
Wogonin Phase 1 Clinical Shandong Buchang Pharmaceuticals Co Ltd, Hefei Cosource Medicine Technology, Daewoong Pharmaceutical Co Ltd, China Pharmaceutical University Respiratory Tract Infections; Neoplasms Details
Etanercept biosimilar (Clover Biopharmaceuticals) SCB-808 Phase 3 Clinical Sichuan Sanyecao Bio-Pharmaceutical Co Ltd Spondylitis, Ankylosing; Arthritis, Rheumatoid; Thrombocytopenia Details
ABBV-257 DVD-1; ABBV-257; DVD-Ig-1 Abbott Laoratories Details
HMPL-004 (Hutchison Medipharma) HMPL-004 Hutchison Medipharma Ltd Details
Infliximab biosimilar (Biocad) BCD-055 Biocad Details
Tumour necrosis factor alpha kinoid TNF-K; TNF-K005 Neovacs Details
Monoclonal Antibody (Mab) sB24M Phase 1 Clinical Pyoderma Gangrenosum Details
ME-3183 ME-3183 Phase 1 Clinical Meiji Seika Pharma Co Ltd Psoriasis Details
Isomyosamine MYMD-1 Phase 2 Clinical Mymd Pharmaceuticals Inc Healthy Aging Details
Adalimumab biosimilar(Incepta) Phase 3 Clinical Incepta Pharmaceuticals Ltd Arthritis, Rheumatoid Details
IA-14069 IA-14069 ILAb Co Ltd Details
Ozoralizumab TS-152; ATN-103; PF-5230896; PF-05230896 Ablynx Details
JNJ-61178104 JNJ-61178104 Phase 1 Clinical Janssen Global Services Llc Autoimmune Diseases Details
V-565 V-565 Vhsquared Details
CC-11050 CC-11050 Celgene Corp Details
COVA-322 COVA-322 Covagen Details
EYS-606 EYS-606 Eyevensys Details
Golimumab biosimilar (Bio-thera) BAT-2506 Phase 3 Clinical Bio-Thera Solutions Ltd Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Arthritis, Psoriatic; Arthritis Details
Etanercept biosimilar (Coherus Biosciences) CHS-0214; BAX-2200 Coherus Biosciences Inc Details
CC-10015 CC-10015 Celgene Corp Details
Doramapimod BIRB-796-BS; BIRB-0796; BIRB-796; BIBR-796 C.H. Boehringer Sohn Ag & Co. Kg Details
AVX-470 AVX-470; AVX-1350; AVX-470h Avaxia Biologics Details
Efprezimod alfa CD24-Fc; HAS-CD24; CD24-Fc-IgG; MK-7110; MK7110 Phase 1 Clinical Oncoimmune Graft vs Host Disease; Coronavirus Disease 2019 (COVID-19) Details
Hemay007 Hemay-007 Phase 2 Clinical Tianjin Hemay Bio-Tech Co Ltd Arthritis, Rheumatoid; Colitis, Ulcerative Details
LY-3114062 LY3114062; LY-3114062 Eli Lilly And Company Details
Tanfanercept HBM-9036; HL-036 Phase 3 Clinical Hanall Dry Eye Syndromes; Xerophthalmia Details
Recombinant human anti-TNFα monoclonal antibody (Qilu Pharmaceutical) Phase 1 Clinical Qilu Pharmaceutical Co Ltd Arthritis, Rheumatoid; Spondylitis, Ankylosing Details
Recombinant anti-TNFα antibody (Shanghai Xiesheng Medicine) Phase 1 Clinical Shanghai Harmony Pharmaceutical Technology Co Ltd Details
Adalimumab biosimilar (DZM Biotech) Phase 1 Clinical Dzm Biotech Ltd Arthritis, Rheumatoid Details
Adalimumab biosimilar (Genor Biopharma) GB-232; BCD-100 Phase 2 Clinical Genor Biopharma Co Ltd Carcinoma, Renal Cell; Arthritis, Rheumatoid; Lung Neoplasms; Melanoma Details
PM-1016 PM1016; TILT-123 Phase 2 Clinical Tilt Biotherapeutics Ltd Solid tumours; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Melanoma Details
Etanercept biosimilar (Suzhou Genemen Biotech) BF-02; GM-02 Phase 1 Clinical Suzhou Genemen Biotech Co Ltd Spondylitis, Ankylosing Details
Adalimumab biosimilar (Prestige BioPharma) PBP-1502 Phase 1 Clinical Prestige Biopharma Details
Adalimumab biosimilar (Alphamab) KN-002 Phase 1 Clinical Suzhou Alphamab Co Ltd Arthritis, Rheumatoid; Asthma Details
Recombinant human monoclonal antibody specific for human tumor necrosis factor (North China Pharmaceutical) Phase 1 Clinical North China Pharmaceutical Company Ltd Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis Details
Guselkumab/Golimumab JNJ-78934804 Phase 2 Clinical Janssen Research & Development Llc Colitis, Ulcerative; Crohn Disease Details
Hemay-005 Hemay-005 Phase 3 Clinical Hainan Hailing Chemipharma Corporation Ltd, Tianjin Hemay Pharmaceutical Co Ltd Spondylitis, Ankylosing; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Pulmonary Disease, Chronic Obstructive; Behcet Syndrome; Dermatitis, Atopic; Plaque psoriasis Details

This web search service is supported by Google Inc.

totop