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Your Position: > Protein > CD300a > CDA-H52H5

Human CD300a / LMIR1 Protein, His Tag (MALS verified)

  • Synonym
    CD300A,CLM-8,CMRF-35-H9,CMRF35-H9,CMRF35-H,IRC1,IRC2,IgSF12,IRp60,CMRF35H,IGSF12,LMIR1
  • Source
    Human CD300a Protein, His Tag(CDA-H52H5) is expressed from human 293 cells (HEK293). It contains AA Leu 18 - Ser 128 (Accession # Q9UGN4-1).
  • Molecular Characterization
    CD300a Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 14.4 kDa. The protein migrates as 16 kDa and 19-26 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
CD300a SDS-PAGE

Human CD300a Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

SEC-MALS
CD300a MALS images

The purity of Human CD300a Protein, His Tag (Cat. No. CDA-H52H5) is more than 85% and the molecular weight of this protein is around 16-24 kDa verified by SEC-MALS.

  • Background
    CD300a, expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6.
  • Clinical and Translational Updates

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재고상품 출발날짜: 영업일 기준 4일

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  • Latest Research Phase:Preclinical

Datasheet & Documentation

DMF 신청
DMF (Drug Master File)

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