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Your Position: > Protein > PTX3 > PT3-M52H6

Mouse PTX3 / TSG-14 Protein, His Tag

  • Synonym
    Pentraxin 3,TSG-14,TNFAIP5,Pentraxin-related protein PTX3,PTX3
  • Source
    Mouse PTX3, His Tag(PT3-M52H6) is expressed from human 293 cells (HEK293). It contains AA Glu 18 - Ser 381 (Accession # P48759-1).
    Predicted N-terminus: Glu 18
  • Molecular Characterization
    PTX3 Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 41.9 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
PTX3 SDS-PAGE

Mouse PTX3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

Bioactivity-ELISA
 PTX3 ELISA

Immobilized Anti-PTX3 Antibody at 1 μg/mL (100 μL/well) can bind Mouse PTX3, His Tag (Cat. No. PT3-M52H6) with a linear range of 0.008-0.5 μg/mL (Routinely tested).

  • Background
    PTX3 is a prototypic long pentraxin consisting of a C-terminal 203-amino acid pentraxin-like domain coupled with an N-terminal 178-amino acid unrelated portion. Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. PTX3 can binds to C1q, but not C1s.
  • Clinical and Translational Updates

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재고상품 출발날짜: 영업일 기준 4일

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Datasheet & Documentation

DMF 신청
DMF (Drug Master File)

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