로그인 회원가입
icon_bulk_order대량 주문 Acrobiosystems for English
0
장바구니가 비어 있습니다
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: > Protein > GITR Ligand > GIL-M526x

Mouse GITR Ligand / TNFSF18 Protein, Fc Tag

  • 동의어
    TNFSF18,AITRL,TL6,hGITRL,GITR Ligand
  • 출처
    Mouse GITR Ligand, Fc Tag (GIL-M526x) is expressed from human 293 cells (HEK293). It contains AA Thr 47 - Ser 173 (Accession # AAO89011).
  • 분자 표징
    Online(Thr 47 - Ser 173) AAO89011

    This protein carries a human IgG1 Fc tag at the N-terminus.

    The protein has a calculated MW of 41.4 kDa. As a result of glycosylation, the protein migrates as 45 kDa under reducing (R) condition, and 80-100 kDa under non-reducing (NR) condition (SDS-PAGE).

  • 내독소
    Less than 1.0 EU per μg by the LAL method.
  • 순도

    >95% as determined by SDS-PAGE.

  • 레시피

    Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • 재구성

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 보관

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Mouse GITR Ligand, Fc Tag (Cat. No. GIL-M526x) SDS-PAGE gel

Mouse GITR Ligand, Fc Tag on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

Bioactivity-ELISA
Mouse GITR Ligand, Fc TagMouse GITR Ligand, Fc Tag (Cat. No. GIL-M526x) ELISA bioactivity

Immobilized Mouse GITR, His Tag (Cat. No. GIR-M5220) at 5 μg/mL (100 μL/well) can bind Mouse GITR Ligand, Fc Tag (Cat. No. GIL-M526x) with a linear range of 5-156 ng/mL (QC tested).

  • 백그라운드
    Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

코멘트 (0)


재고상품 도착 날짜: 영업일 기준 4일

가격(KRW) : 525,000

가격(KRW) : 3,465,000

보급 및 전시



약물 개발 현황

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:0 Details
  • Latest Research Phase:Preclinical

Datasheet & Documentation

DMF 신청
DMF (Drug Master File)

신제품

문의와 컨텐츠

This web search service is supported by Google Inc.

totop