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Your Position: > Antibody > Tbr1 > TB1-S457

Polyclonal Tbr1 Antibody, Rabbit IgG

  • Source
    Polyclonal Tbr1 Antibody, Rabbit IgG is a polyclonal antibody purified from rabbit serum.
    Gene Synonyms: TBR1, T-box brain transcription factor 1, T-box brain gene 1.
  • Species

    Rabbit polyclonal antibodies

  • Isotype

    Rabbit IgG

  • Antibody Type

    Polyclonal Antibody

  • Reactivity

    Mouse, rat, human; Others have not been tested

  • Immunogen

    Mouse TBR1 peptide fused to GST.

  • Specificity

    Usually, it is easier to get a positive signal in sections of juvenile animal tissues than that of adults. Immunogen: Mouse TBR1 peptide fused to GST.

  • Application
    ApplicationRecommended Usage
    IF1:200~500
  • Purification

    Protein A purified/ Protein G purified

  • Formulation

    Supplied as 0.2 μm filtered solution in pH7.4, PBS, 65 mM Tris, 50 Mm Glycine with 40% glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with blue ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Shipped at -20°C. Store at -20 for 3 years and -80°C for 5 years. Avoid freeze/thaw cycle.
Immunostaining
 Tbr1 IMMUNOSTAINING

2D cell staining: Immunofluorescent staining (10X) of cerebral organoid-derived neurons (CIPO-BWL001K) labeling Tbr1 (Red) with purified TB1-S457 at 1:200 dilution. DAPI (blue) was used as nuclear counterstain.

  • Background
    The neuron-specific transcription factor T-box brain 1 (Tbr1) is a transcription factor that is highly expressed in glutamatergic early-born cortical neurons, and is specifically expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb. Tbr1 is thought to play an important role in neuronal migration and axonal projection during cortical development. Tbr1-/- mice have been characterized by neonatal lethality, severe defects in the axonal projections of the cerebral cortex and impairment of neuronal migration of the cerebral cortex and amygdala.

    Huang TN, et al. Nat Neurosci. 2014;17(2):240-7. doi: 10.1038/nn.3626.

    Hevner RF, et al. Neuron. 2001;29(2):353-66. doi: 10.1016/s0896-6273(01)00211-2.

    General Notes: FOR RESEARCH USE ONLY.
  • Clinical and Translational Updates

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재고상품 출발날짜: 영업일 기준 4일

가격(KRW) : 120,000

가격(KRW) : 525,000

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Datasheet & Documentation

DMF 신청
DMF (Drug Master File)

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