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Your Position: > Protein > HLA-E*0103 & B2M & CMV UL40 (VMAPRTVIL) > HLU-HP2H3

PE-Labeled Human HLA-E*01:03&B2M&CMV UL40 (VMAPRTVIL) Tetramer Protein

  • Synonym
    HLA-E*0103 & B2M & CMV UL40 (VMAPRTVIL)
  • Source
    PE-Labeled Human HLA-E*01:03&B2M&CMV UL40 (VMAPRTVIL) Tetramer Protein(HLU-HP2H3) is expressed from human 293 cells (HEK293). It contains AA Gly 22 - Ile 305 (HLA-E*01:03) & Ile 21 - Met 119 (B2M) & VMAPRTVIL peptide (Accession # P13747 (HLA-E*01:03) & P61769-1 (B2M) & VMAPRTVIL).
    Predicted N-terminus: Gly 22 & Val
  • Molecular Characterization

    PE-Labeled Human HLA-E*01:03&B2M&CMV UL40 (VMAPRTVIL) Tetramer Protein is assembled by biotinylated monomer (HL0-H82E6) and PE-labeled streptavidin.

    Biotinylated Human HLA-E*01:03&B2M&CMV UL40 (VMAPRTVIL) Complex Protein is produced by co-expression of HLA and B2M loaded with CMV UL40 peptide. Biotinylated Human HLA-E*01:03&B2M&CMV UL40 (VMAPRTVIL) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, 1% BSA, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
  • Clinical and Translational Updates

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재고상품 출발날짜: 영업일 기준 4일

가격(KRW) : 594,000

가격(KRW) : 3,420,000

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