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Your Position: > Antibody > A35R (MPXV) > A3R-M575

Monoclonal Anti-Monkeypox-A35R Antibody, Human IgG1 (6F11) (MALS verified)

  • Source

    Monoclonal Anti-Monkeypox-A35R Antibody, Human IgG1 (6F11) is a chimeric monoclonal antibody recombinantly expressed from HEK293, which combines the variable region of a mouse monoclonal antibody with Human constant domain.

  • Clone

    6F11

  • Isotype

    Human IgG1 | Human Kappa

  • Conjugate

    Unconjugated

  • Antibody Type

    Recombinant Monoclonal

  • Reactivity

    Virus

  • Immunogen

    Recombinant Monkeypox virus (strain Zaire-96-I-16) A35R derived from human 293 cells.

  • Specificity

    This product is a specific antibody specifically reacts with A35R (MPXV).

  • Application
    ApplicationRecommended Usage
    ELISA0.1-75 ng/mL 
  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Purification

    Protein A purified/ Protein G purified

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
A35R (MPXV) SDS-PAGE

Monoclonal Anti-Monkeypox-A35R Antibody, Human IgG1 (6F11) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

SEC-MALS
A35R (MPXV) MALS images

The purity of Monoclonal Anti-Monkeypox-A35R Antibody, Human IgG1 (6F11) (Cat. No. A3R-M575) is more than 90% and the molecular weight of this protein is around 135-155 kDa verified by SEC-MALS.

Bioactivity-ELISA
 A35R (MPXV) ELISA

Immobilized Monkeypox virus (strain Zaire-96-I-16) A35R , His Tag (Cat. No. A3R-M52H3) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Monkeypox-A35R Antibody, Human IgG1 (6F11) (Cat. No. A3R-M575) with a linear range of 0.1-2 ng/mL (QC tested).

 A35R (MPXV) ELISA

Immobilized Monkeypox virus (Democratic Republic of the Congo) A35R Protein, His Tag (Cat. No. A3R-M52H4) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Monkeypox-A35R Antibody, Human IgG1 (6F11) (Cat. No. A3R-M575) with a linear range of 0.1-3 ng/mL (Routinely tested).

Bioactivity-SPR
 A35R (MPXV) SPR

Monoclonal Anti-Monkeypox-A35R Antibody, Human IgG1 (6F11) (Cat. No. A3R-M575) captured on Protein A Chip can bind Monkeypox virus (strain Zaire-96-I-16) A35R , His Tag (Cat. No. A3R-M52H3) with an affinity constant of 0.269 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

  • Background
    Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded DNA. The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa, multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. after the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. The envelope glycoprotein A35R on the EV surface has been predicted to influence intercellular diffusion of virions.
  • Clinical and Translational Updates

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재고상품 출발날짜: 영업일 기준 4일

가격(KRW) : 555,000

가격(KRW) : 3,660,000

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Datasheet & Documentation

DMF 신청
DMF (Drug Master File)

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