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Your Position: > Antibody > MMAE > MME-PLS104

HRP conjugated Monoclonal Anti-MMAE&MMAF Antibody,Mouse IgG1

  • Source
    HRP conjugated Monoclonal Anti-MMAE&MMAF Antibody,Mouse IgG1 is recombinantly produced from human 293 cells (HEK293).
  • Isotype
    Mouse IgG1/kappa
  • Specificity
    Specifically recognizes the target-MMAE.
  • Application
    This Monoclonal anti-MMAE antibody is designed for use in ELISA and PK environment.
  • Purity

    >95% as determined by SDS-PAGE.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 24 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
MMAE SDS-PAGE

HRP conjugated Monoclonal Anti-MMAE&MMAF Antibody,Mouse IgG1 on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

Bioactivity-Elisa
 MMAE ELISA

Immobilized Disitamab Vedotin at 1 μg/mL (100 μL/well) can bind HRP conjugated Monoclonal Anti-MMAE&MMAF Antibody,Mouse IgG1 (Cat. No. MME-PLS104) with a linear range of 0.5-16 ng/mL (QC tested).

  • Background
    Monomethyl auristatin E (MMAE) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types. Anti-MMAE antibody is a Mouse monoclonal antibody. This antibody has been shown to work in applications such as: PK, PD, Immunoassay and ELISA.
  • Clinical and Translational Updates

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재고상품 출발날짜: 영업일 기준 4일

가격(KRW) : 525,000

가격(KRW) : 2,070,000

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Datasheet & Documentation

DMF 신청
DMF (Drug Master File)

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