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Your Position: > Protein > IdeS > IDS-S5143

IdeS (70U/μl)

  • Product Details
    This product is derived from Streptococcus pyogenes and expressed in E. coli, it is an IgG-specific cysteine protease that digests antibodies at a single amino acid site below the hinge, generating homogenous F(ab’)2 and Fc fragments.
  • Application
    1. IdeS cleaves IgG to produce F(ab')2 and Fc fragments at specific site.
  • Unit Definition
    One unit digests ≥ 95% of 1 μg human IgG when incubated in 10 mM sodium phosphate, 137 mM NaCl, 2.7 mM KCl, pH7.4 at 37°C for 30min.
  • Quility Control
    Less than 1.0 EU per μg by the LAL method. >95% as determined by SDS-PAGE.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Storage

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
Bioactivity
 IdeS ENZYME

50/100unit Ides digests ≥ 95% of 100 µg human IgG when incubated in PBS pH 7.4 at 37℃ for 30min.

 IdeS ENZYME

50/100unit Ides digests ≥ 95% of 100 µg human IgG when incubated in PBS pH 7.4 at 37℃ for 30min.

  • Clinical and Translational Updates

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Datasheet & Documentation

DMF 신청
DMF (Drug Master File)

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