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Your Position: > Protein > IdeS > IDS-S5143

IdeS (70U/μl)

  • Product Details
    This product is derived from Streptococcus pyogenes and expressed in E. coli, it is an IgG-specific cysteine protease that digests antibodies at a single amino acid site below the hinge, generating homogenous F(ab’)2 and Fc fragments.
  • Application

    IdeS cleaves IgG to produce F(ab')2 and Fc fragments at specific site.

  • Unit Definition
    One unit digests ≥ 95% of 1 μg human IgG when incubated in 10 mM sodium phosphate, 137 mM NaCl, 2.7 mM KCl, pH7.4 at 37°C for 30min.
  • Purity

    >95% as determined by SDS-PAGE.

  • Enzyme Activity
    >70 U/μL
  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, PH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Storage

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
Bioactivity
 IdeS ENZYME

Bioactivity of IdeS is confirmed by the cleavage of Human IgG as analyzed by SDS-PAGE (QC tested).

 IdeS ENZYME

50/100unit Ides digests ≥ 95% of 100 µg human IgG when incubated in PBS pH 7.4 at 37℃ for 30min (Routinely tested).

 IdeS ENZYME

50/100unit Ides digests ≥ 95% of 100 µg human IgG when incubated in PBS pH 7.4 at 37℃ for 30min (Routinely tested).

  • Clinical and Translational Updates

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재고상품 출발날짜: 영업일 기준 4일

가격(KRW) : 312,000

가격(KRW) : 2,047,500

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Datasheet & Documentation

DMF 신청
DMF (Drug Master File)

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