로그인 회원가입
icon_bulk_order대량 주문 조회 Acrobiosystems for English
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: > Cytokines > VEGF R3 > FL4-H5251

Human VEGF R3 / FLT4 Protein, Fc Tag (MALS verified)

  • 동의어
    Flt-4,FLT4,LMPH1A,PCLFLT41,VEGFR3,VEGFR-3,FLT-4,FLT-41,FLT41,PCL
  • 출처
    Human VEGF R3, Fc Tag (FL4-H5251) is expressed from human 293 cells (HEK293). It contains AA Tyr 25 - Ile 776 (Accession # NP_002011.2).
    Predicted N-terminus: Tyr 25
  • 분자 표징
    Online(Tyr  25 - Ile 776) NP_002011.2

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 111.2 kDa. As a result of glycosylation, the protein migrates as 140-160 kDa under reducing (R) condition, and 280-320 kDa under non-reducing (NR) condition (SDS-PAGE).

  • 내독소
    Less than 1.0 EU per μg by the LAL method.
  • 순도

    >95% as determined by SDS-PAGE.

  • 레시피

    Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • 재구성

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 보관

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human VEGF R3, Fc Tag (Cat. No. FL4-H5251) SDS-PAGE gel

Human VEGF R3, Fc Tag on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS
Human VEGF R3, Fc Tag (Cat. No. ) MALS images

The purity of Human VEGF R3, Fc Tag (Cat. No. FL4-H5251) is more than 85% and the molecular weight of this protein is around 260-320 kDa verified by SEC-MALS.

Bioactivity-ELISA
Human VEGF R3, Fc TagHuman VEGF R3, Fc Tag (Cat. No. FL4-H5251) ELISA bioactivity

Immobilized Human VEGF-C, His Tag (Cat. No. VEC-H4225) at 5μg/mL (100 μL/well) can bind Human VEGF R3, Fc Tag (Cat. No. FL4-H5251) with a linear range of 0.6-10 ng/mL (QC tested).

Human VEGF R3, Fc TagHuman VEGF R3, Fc Tag (Cat. No. FL4-H5251) ELISA bioactivity

Immobilized Human VEGF R3, Fc Tag (Cat. No. FL4-H5251) at 5μg/mL (100 μL/well) can bind Human VEGF-D, His Tag (Cat. No. VED-H5228) with a linear range of 0.08-0.6 μg/mL (Routinely tested).

Bioactivity-SPR
Human_FcRn_Heterodimer_Protein_SPR

Human VEGF R3, Fc Tag (Cat. No. FL4-H5251) captured on CM5 chip via Anti-human IgG Fc antibodies surface can bind Human VEGF-D, His Tag (Cat. No. VED-H5228) with an affinity constant of 19.7 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

Human_FcRn_Heterodimer_Protein_SPR

Human VEGF-C, His Tag (Cat. No. VEC-H4225) captured on CM5 Chip via anti-His antibody can bind Human VEGF R3, Fc Tag (Cat. No. FL4-H5251) with an affinity constant of 41.1 pM as determined in SPR assay (Biacore T200) (Routinely tested).

  • 백그라운드
    Vascular endothelial growth factor receptor 3 (VEGF R3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). VEGF R3 mediates lymphangiogenesis in response to VEGF-C and VEGF-D. VEGF R3 is widely expressed in the early embryo but becomes restricted to lymphatic endothelia at later stages of development. It is likely that VEGF R3 may be important for lymph angiogenesis.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

코멘트 (0)


ETD of in-stock products: 4 business days

가격(KRW) : 435,000

가격(KRW) : 3,270,000

보급 및 전시



약물 개발 현황

  • Number of Launched Drugs:12 Details
  • Number of Drugs in Clinical Trials:11 Details
  • Latest Research Phase:Approved

데이터 테이블 및 파일

DMF 신청
DMF (Drug Master File)

연락처

+1  800-810-0816 (US)
+86 400-682-2521 (AP)

신제품

의문 과 코맨트

This web search service is supported by Google Inc.

totop