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Your Position: > Protein > Cystatin S > CS4-H5223

Human Cystatin S / CST4 Protein, His Tag

  • Synonym
    CST4,Cystatin-4,Cystatin-S,Cystatin-S5,Cystatin-SA-III
  • Source
    Human Cystatin S, His Tag(CS4-H5223) is expressed from human 293 cells (HEK293). It contains AA Ser 21 - Ala 141 (Accession # AAH65714).
    Predicted N-terminus: Ser 21
  • Molecular Characterization
    Cystatin S Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 15.0 kDa. The protein migrates as 15 kDa under reducing (R) condition (SDS-PAGE).

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 25 mM MES, 150 mM NaCl, pH6.0 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Cystatin S SDS-PAGE

Human Cystatin S, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • Background
    Cystatin-4 (CST4) is also known as Cystatin-S, Salivary acidic protein 1, which is a secreted protein, which belongs to the cystatin family. Cystatin-S is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level) and is also expressed in saliva, tears, urine and seminal fluid. Cystatin-4 / Cystatin S strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively.
  • Clinical and Translational Updates

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재고상품 출발날짜: 영업일 기준 4일

가격(KRW) : 375,000

가격(KRW) : 2,100,000

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DMF (Drug Master File)

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