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Your Position: > IgG2a Fc

IgG2a Fc

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IGA-M5207-BLI
 IgG2a Fc BLI

Loaded Mouse FCGRT&B2M Heterodimer Protein, His Tag&Twin-Strep Tag (BLI verified) (Cat. No. FCM-M52W2) on NTA Biosensor, can bind Mouse IgG2a Fc, Tag Free(Cat. No. IGA-M5207) with an affinity constant of 7.73 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

IGA-M5207-BLI
 IgG2a Fc BLI

Loaded Mouse FCGRT&B2M Heterodimer Protein, His Tag (BLI verified) (Cat. No. FCM-M52W8) on NTA Biosensor, can bind Mouse IgG2a Fc, Tag Free(Cat. No. IGA-M5207) with an affinity constant of 5.75 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Synonym Name

IgG2A

Background

Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-? (IgG) antibody molecules changes in rheumatoid arthritis.

Clinical and Translational Updates

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