로그인 회원가입
icon_bulk_order대량 주문 Acrobiosystems for English
Promotion
Recombinant Proteins ClearClear history
Recombinant Proteins CloseClose
Browse Products By Molecule Name a-zA-Z
TL1A Hot |GMP IL-2 Hot |Claudin 18.2 Hot |FMC 63 Ab  |FcRn
0
장바구니가 비어 있습니다
내 장바구니
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: 홈 > Nectin-2

Nectin-2

요약

Name:Transmembrane protein PVRIG
Target Synonym:PVRIG,PVR Related Immunoglobulin Domain Containing,CD112 Receptor,Poliovirus Receptor-Related Immunoglobulin Domain-Containing Protein,Poliovirus Receptor Related Immunoglobulin Domain Containing,Nectin-2 Receptor,C7orf15,CD112R,Transmembrane Protein PVRIG,MGC2463
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:7
Lastest Research Phase:Phase 2 Clinical

제품 리스트 구매

제품> 결과 필터링
제품 상태별:
제품 유형별 :
종별:
태그별:
결합물별:
제품번호 종 제품 설명 구조 순도 특징
CD2-H82E7 Human Biotinylated Human Nectin-2 / CD112 Protein, His,Avitag™ (MALS verified)
CD2-H82E7-structure
CD2-H82E7-sds
CD2-H82A3 Human Biotinylated Human Nectin-2 / CD112 Protein, Mouse IgG2a Fc,Avitag™ (MALS verified)
CD2-H82A3-structure
CD2-H82A3-sds
CD2-H5257 Human Human Nectin-2 / CD112 Protein, Mouse IgG2a Fc Tag
CD2-H5257-structure
CD2-H5257-sds
CD2-H82F8 Human Biotinylated Human Nectin-2 / CD112 Protein, Fc,Avitag™ (HPLC verified)
CD2-H82F8-structure
CD2-H82F8-sds
CD2-H82F8-hplc
PV2-H5253 Human Human Nectin-2 / CD112 Protein, Fc Tag
PV2-H5253-structure
PV2-H5253-sds
PV2-H52E2 Human Human Nectin-2 / CD112 Protein, His Tag
PV2-H52E2-structure
PV2-H52E2-sds

일부의 생물활성 데이터

CD2-H5257-BLI
Nectin-2 BLI

Loaded Human Nectin-2, Mouse IgG2a Fc Tag (Cat. No. CD2-H5257) on Protein A Biosensor, can bind Human PVRIG, His Tag (Cat. No. PVG-H52H4) with an affinity constant of 1.33 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol
PV2-H5253-BLI
Human_FcRn_Heterodimer_Protein_Bli

Loaded Human Nectin-2, Fc Tag (Cat. No. PV2-H5253) on Protein A Biosensor, can bind Human PVRIG, His Tag (Cat. No. PVG-H52H4) with an affinity constant of 0.456 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol

Synonym Name

CD112,Nectin-2,PVRL2

Background

Poliovirus receptor-related 2 (PVRL2) is also known as nectin-2 and CD112 (formerly herpesvirus entry mediator B, HVEB),  which is a human plasma membrane glycoprotein. PVRL2 is one of the plasma membrane components of adherens junctions. PVRL2 also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in PVRL2 gene have been associated with differences in the severity of multiple sclerosis. Also, PVRL2 binds with low affinity to TIGIT. Furthermore, PVRL2 acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV).

Clinical and Translational Updates

Related Molecule

TIGIT DNAM-1

임상 약품 정보

Name Research Code Research Phase Company Indications Clinical Trials
COM-701 COM-701 Phase 2 Clinical Compugen Ltd Ovarian Neoplasms; Head and Neck Neoplasms; Solid tumours; Small Cell Lung Carcinoma; Triple Negative Breast Neoplasms; Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Lung Neoplasms Details
SIM-0348 SIM-0348 Phase 1 Clinical Simcere Pharmaceutical Group Ltd Solid tumours; Neoplasms Details
GSK-4381562 SRF-813; GSK-4381562 Phase 1 Clinical Surface Oncology Inc Neoplasms Details
NM1F NM1F; TGI-2 Phase 1 Clinical Hefei TG ImmunoPharma Co Ltd Solid tumours; Ovarian Neoplasms; Triple Negative Breast Neoplasms; Colorectal Neoplasms; Melanoma Details
SHR-2002 SHR-2002 Phase 1 Clinical Suzhou Suncadia Biopharmaceuticals Co Ltd, Shanghai Hengrui Pharmaceutical Co Ltd Neoplasms Details
JS-009 JS009; TAB009; JS-009 Phase 1 Clinical Shanghai Junshi Biosciences Co Ltd Solid tumours; Neoplasms Details
PM-1009 PM1009 Phase 1 Clinical Biotheus Inc Solid tumours; Neoplasms; Lung Neoplasms Details

This web search service is supported by Google Inc.

totop
Call us
우리에게 전화하세요
글로벌: +1 800-810-0816 (무료)
아시아태평양: +86 400-682-2521
Email
이메일
order.kr@acrobiosystems.com
Fax
팩스
+1 888-377-6111
Address
주소
서울 성동구 왕십리로10길 6 서울숲비즈포레 703
회사명
아크로바이오 주식회사
사업자 등록번호
186-88-02858
대표자
CHEN YIDING
사업장주소
서울특별시 송파구 중대로12길 10-20, 1층 셀렉티드송파(가락동)
linkedin twitter facebook youtube

문의

Copyright © 2017 ACROBiosystems. All Rights Reserved
Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap