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Flow Cytometry assay shows that Human CD27 Protein, Mouse IgG2a Fc Tag (Cat. No. CD7-H5257) can bind to Raji cells Surface Human CD70. The concentration of CD27 used is 10 μg/mL (Routinely tested).
Immobilized Human CD27, His Tag (Cat. No. CD7-H522b) at 2 μg/mL (100 μL/well) can bind Biotinylated Human CD27 Ligand Protein, Avitag,Fc Tag (Cat. No. TN7-H82F5) with a linear range of 1-31 ng/mL (QC tested).
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
Anti-CD27 monoclonal antibody (Aduro Biotech) | BION-1402 | Phase 1 Clinical | Aduro Biotech Inc | Neoplasms | Details |
GEN-1053 | BNT-313; GEN-1053 | Phase 2 Clinical | Genmab A/S | Solid tumours | Details |
Boserolimab | MK-5890 | Phase 2 Clinical | Merck & Co Inc | Solid tumours; Small Cell Lung Carcinoma; Triple Negative Breast Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
LOR-S03 | CDX-527 | Phase 1 Clinical | Celldex Therapeutics | Ovarian Neoplasms; Solid tumours; Liver Neoplasms; Head and Neck Neoplasms; Stomach Neoplasms; Carcinoma, Renal Cell; Esophageal Neoplasms; Neoplasms; Microsatellite instability-high cancer; Urinary Bladder Neoplasms; Cholangiocarcinoma; Breast Neoplasms; Colorectal Neoplasms; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
Varlilumab | CDX-1127 | Phase 2 Clinical | Celldex Therapeutics | Gallbladder Neoplasms; Lymphoma, Primary Effusion; Cholangiocarcinoma; Lymphoma, Mantle-Cell; Bile Duct Neoplasms; Urologic Neoplasms; Astrocytoma; Lymphoma, T-Cell; Burkitt Lymphoma; Lymphoma, Non-Hodgkin; Plasmablastic Lymphoma; Lung Neoplasms; Urogenital Neoplasms; Lymphoma; Glioma; Melanoma; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Large B-Cell, Diffuse; Biliary Tract Neoplasms; Head and Neck Neoplasms; Kidney Neoplasms; Solid tumours; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Lymphomatoid Granulomatosis; Skin Neoplasms; Lymphoma, B-Cell; Kidney Diseases; Neoplasms; Glioblastoma; Triple Negative Breast Neoplasms; Urologic Diseases; Urinary Bladder Neoplasms; Oligodendroglioma; Prostatic Neoplasms | Details |
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