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| Project Name | Modality | Therapeutic Area | Indications | Stage | Right Available |
| A2aR/A2bR Antagonist | Small molecule | Oncology/Cancer | Advanced solid tumor,Advanced hematological tumor | IND | Global (except China) |
| 제품번호 | 종 | 제품 설명 | 구조 | 순도 | 특징 |
|---|---|---|---|---|---|
| ADA-H52H5 | Human | Human ADORA2A Protein, His Tag (Detergent, Inhibitor added) |  |
|
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| ADA-H52P4 | Human | Human ADORA2A Full Length Protein (VLP) |
Anti-ADORA2A antibody-3F6-9G5 captured on CM5 chip via Anti-human IgG Fc antibodies surface can bind Human ADORA2A Protein, His Tag (Cat. No. ADA-H52H5) with an affinity constant of 21.8 nM as determined in a SPR assay (in presence of DDM and CHS) (Biacore 8K) (Routinely tested).
| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Acetaminophen/Propyphenazone/Caffeine | Approved | 散利痛, 散列通 | Common Cold | Details | ||||||
| Caffeine/Ergotamine Tartrate | Approved | Novartis Pharma Ag | Cafergot | Mainland China | Migraine Disorders | Tianjin Medical University Pharmaceutical Factory | 1948-11-26 | Migraine Disorders | Details | |
| Aspirin/Acetaminophen/Caffeine/Chlorphenamine Maleate | Approved | Common Cold | Details | |||||||
| Acetaminophen/Pseudoephedrine Hydrochloride/Caffeine | Approved | Common Cold | Details | |||||||
| Norethidranum Dipropionas/Caffeine/Vitamin B6 | Approved | Mainland China | Contraception | Huazhong Pharmaceutical Co Ltd | 1981-01-01 | Contraception | Details | |||
| Aspirin/Caffeine/Chlorphenamine Maleate/Tartaric Acid | Approved | Common Cold | Details | |||||||
| Acetaminophen/Caffeine/Phenylephrine Hydrochloride/Chlorphenamine Maleate/Vitamin B | Approved | Details | ||||||||
| Ferric Ammonium Citrate/Vitamin B1/Sodium glycerophosphate/Caffeine | Approved | Ischemia | Details | |||||||
| Aspirin/Caffeine | Approved | Common Cold | Details | |||||||
| Aminophenazone/Caffeine | Approved | Fever | Details | |||||||
| Oxtriphylline | Approved | Theocolin | Canada | null | Asthma | Details | ||||
| Aminophenazone/Caffeine/Chlorphenamine Maleate | Approved | Headache; Common Cold; Neuralgia | Details | |||||||
| Acetaminophen/Caffeine/Pseudoephedrine Hydrochloride/Chlorphenamine Maleate | Approved | Common Cold | Details | |||||||
| Aspirin/Caffeine/Codeine Phosphate | Approved | 柯克 | Pain | Details | ||||||
| Sodium glycerophosphate/Caffeine/Vitamin B/Phosphoric Acid/Niacin | Approved | Details | ||||||||
| Brompheniramine Maleate/Bromhexine Hydrochloride/Caffeine/Acetaminophen/Phenylephrine Hydrochloride | Approved | Common Cold | Details | |||||||
| Acetaminophen/Caffeine/Chlorphenamine Maleate | Approved | Common Cold | Details | |||||||
| Acetaminophen/Chlorphenamine Maleate/Caffeine/Guaifenesin | Approved | Common Cold | Details | |||||||
| Acetaminophen/Amantadine Hydrochloride/Caffeine/Chlorphenamine Maleate/Artificial Bezoar | Approved | 复方氨酚烷胺 | Mainland China | Common Cold | null | 1984-01-01 | Common Cold | Details | ||
| Aminophenazone/Phenacetin/Caffeine/Phenobarbital | Approved | Migraine Disorders | Details | |||||||
| Acetaminophen/Salicylamide/Pseudoephedrine Hydrochloride/Caffeine/Triprolidine Hydrochloride Hydrate | Approved | 联邦菲迪乐 | Common Cold | Details | ||||||
| Antipyrine/Caffeine | Approved | Common Cold | Details | |||||||
| Antipyrine/Caffeine/Citric Acid | Approved | 米格来宁 | Mainland China | Sedation | Xi'An Disai Biological Pharmaceutical Co Ltd, Heilongjiang Hasing Pharmaceutical Group Co Ltd, Huadong Medicine (Xi'An) Bodyguard Pharmaceutical Co Ltd, Mudanjiang Lingtai Medicdment Co Ltd | 1982-01-01 | Sedation | Details | ||
| Caffeine/Metamizole Sodium/Dihydroergotamine Mesylate | Approved | Cefaliv | Migraine Disorders | Details | ||||||
| Acetaminophen/Caffeine/Chlorphenamine Maleate/Artificial Bezoar | Approved | Common Cold | Details | |||||||
| Istradefylline | KW-6002 | Approved | Kyowa Hakko Kirin Co Ltd | Nourianz, Nouriast | Japan | Parkinson Disease | Kyowa Hakko Kirin Co Ltd | 2013-03-25 | Substance-Related Disorders; Restless Legs Syndrome; Parkinsonian Disorders; Sleep Wake Disorders; Parkinson Disease; Cognitive Dysfunction; Hepatic Insufficiency; Movement Disorders; Amyotrophic Lateral Sclerosis | Details |
| Caffeine | Approved | Apnea; Mental Fatigue; Memory Disorders; Cocaine-Related Disorders; Sexual Dysfunction, Physiological; Parkinson Disease; Cognitive Dysfunction; Diabetes Complications; Diabetic Nephropathies; Postoperative Cognitive Complications; Diabetes Mellitus, Type 1; Fatigue; Delirium; Disorders of Excessive Somnolence; Intermittent Claudication; Spinal Cord Injuries; Fetal Membranes, Premature Rupture; Consciousness; Sleepiness | Details | |||||||
| Acetaminophen/Caffeine | Approved | Zentiva As | Mainland China | Pain | Sino--American Shanghai Squibb Pharmaceutical Ltd | Pain | Details | |||
| Sodium Benzoate/Caffeine | Approved | Central Nervous System Diseases | Details | |||||||
| Acetaminophen/Caffeine/Codeine Phosphate/Diphenhydramine Hydrochloride | Approved | 斯力帮 | Headache | Details | ||||||
| Quinine Hydrochloride Hydrate/Caffeine | Approved | Malaria | Details | |||||||
| Adenine | Approved | Leucon | Japan | Leukopenia | Ohara Pharmaceutical Co Ltd | Leukemia; Leukopenia | Details | |||
| Dextromethorphan Hydrobromide/Chlorphenamine Maleate/Sodium Citrate/Ammonium Chloride/Caffeine | Approved | 尔可芬 | Cough | Details | ||||||
| Dihydroergocryptine/Caffeine | Approved | 洛斯宝, VASOBRAL | Diabetic Retinopathy; Diabetes Mellitus | Details | ||||||
| Aminophenazone/Phenacetin/Caffeine | Approved | Pain; Fever | Details | |||||||
| Acetaminophen/Caffeine/Ephedrine Hydrochloride/Diphenhydramine Hydrochloride | Approved | Influenza, Human | Details | |||||||
| Acetaminophen/Amantadine Hydrochloride/Caffeine/Artificial Bezoar | Approved | Common Cold | Details | |||||||
| Regadenoson Hydrate | CVT-3146 | Approved | Astellas Pharma Inc | Lexiscan, Rapiscan | United States | Contrast agents | Astellas Pharma Inc | 2008-04-10 | Myocardial Ischemia; Rejection of lung transplantation; Cardiovascular contrast agents; Pneumonia; Coronary Artery Disease; Heart Diseases; Glioblastoma; Coronavirus Disease 2019 (COVID-19); Retinal Artery Occlusion; Oligodendroglioma; Contrast agents; Cardiovascular Diseases; Astrocytoma; Diagnostic agents; Glioma; Anemia, Sickle Cell | Details |
| Aminophenazone/Caffeine/Calcium Glycerophosphate | Approved | Headache; Dysmenorrhea; Neuralgia | Details | |||||||
| Aspirin/Caffeine/Acetaminophen | Approved | United States | Migraine Disorders | Glaxosmithkline Consumer Healthcare | Migraine Disorders; Anesthesia | Details | ||||
| Aspirin/Phenacetin/Caffeine | Approved | Headache; Dysmenorrhea; Toothache; Neuralgia; Fever; Arthralgia | Details | |||||||
| Acetaminophen/Butalbital/Caffeine | Approved | Headache | Details | |||||||
| Acetaminophen/Methylephedrine Hydrochloride/Dextromethorphan Hydrobromide/Chlorphenamine Maleate/Caffeine/Sulfogaiacol | Approved | Mainland China | Common Cold | Zhejiang Apeloa Kangyu Pharmaceutical Co Ltd | Common Cold | Details | ||||
| Aminophenazone/Acetaminophen/Caffeine/Chlorphenamine Maleate | Approved | 克感敏, 扑感敏, 朴感敏 | Common Cold | Details | ||||||
| Acetaminophen/Chlorphenamine Maleate/Methylephedrine Hydrochloride/Sulfogaiacol/Caffeine | Approved | Mainland China | Common Cold | Hainan Sanfengyou Pharmaceutical Co Ltd | 2006-05-16 | Common Cold | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| Sodium Citrate/Citric Acid/Dextrose/Monosodium phosphate/Adenine/Mannitol/Sodium Chloride | Details | ||||
| Propranolol hydrochloride/Caffeine/Phenytoin Sodium | Details | ||||
| JNJ-86974680 | JNJ-86974680 | Phase 1 Clinical | Johnson & Johnson Enterprise Innovation Inc | Carcinoma, Non-Small-Cell Lung | Details |
| VG081821AC | Phase 2 Clinical | Zhejiang Vimgreen Pharmaceuticals Ltd | Parkinson Disease | Details | |
| ST-4206 | ST-4206 | Phase 1 Clinical | Alfasigma Spa | Parkinson Disease | Details |
| INCB-106385 | INCB-106385 | Phase 1 Clinical | Incyte Corp | Solid tumours; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Esophageal Neoplasms; Triple Negative Breast Neoplasms; Prostatic Neoplasms, Castration-Resistant; Urinary Bladder Neoplasms; Colorectal Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung; Gastrointestinal Neoplasms; Carcinoma, Hepatocellular | Details |
| Ciforadenant | CPI-444; V-81444 | Phase 2 Clinical | Vernalis (R&D) Ltd | Carcinoma, Renal Cell; Neoplasms; Attention Deficit Disorder with Hyperactivity; Multiple Myeloma; Parkinson Disease; Carcinoma, Non-Small-Cell Lung | Details |
| Sodium Citrate/Citric Acid/Dextrose | Details | ||||
| Taminadenant | NIR-178; PBF-509 | Phase 1 Clinical | Palobiofarma Sl | Solid tumours; Ovarian Neoplasms; Head and Neck Neoplasms; Carcinoma, Renal Cell; Carcinoma; Triple Negative Breast Neoplasms; Lymphoma, Large B-Cell, Diffuse; Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Colorectal Neoplasms; Parkinson Disease; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung; Melanoma | Details |
| PORT-8 | PORT-8; TT-53 | Phase 2 Clinical | Solid tumours | Details | |
| Imaradenant | AZD-4635; HTL-1071 | Phase 2 Clinical | Solid tumours; Prostatic Neoplasms, Castration-Resistant | Details | |
| CS-3005 | CS-3005 | Phase 1 Clinical | Cstone Pharmaceuticals (Suzhou) Co Ltd | Solid tumours | Details |
| EXS-21546 | EXS-21546; EVOEXS21546 | Phase 2 Clinical | Exscientia Ltd | Solid tumours; Neoplasms | Details |
| PORT-6 | PORT-6; TT-10 | Phase 2 Clinical | Neoplasms | Details | |
| Ethenzamide/Caffeine/Chlorzoxazone | Details | ||||
| Naproxen/Caffeine | BAY-2880376 | Phase 3 Clinical | Bayer AG | Pain, Postoperative | Details |
| Caffeinol | Phase 3 Clinical | Cardium Therapeutics | Stroke; Alcoholism; Disruptive, Impulse Control, and Conduct Disorders | Details | |
| ILB-2109 | WTS-001; ILB-2109 | Phase 2 Clinical | Hangzhou Wutong Tree Pharmaceutical Co Ltd | Solid tumours; Neoplasms | Details |
| KW-6356 | KW-6356 | Phase 2 Clinical | Kyowa Hakko Kirin Co Ltd | Parkinson Disease; Hepatic Insufficiency | Details |
| Salicylamide/Acetaminophen/Caffeine | Details | ||||
| DZD-2269 | Phase 1 Clinical | Prostatic Neoplasms, Castration-Resistant; Prostatic Neoplasms | Details | ||
| Aspirin/Acetaminophen/Caffeine/Thiamine | Details | ||||
| PBF-999 | PBF-999 | Phase 1 Clinical | Palobiofarma Sl | Neoplasms; Huntington Disease | Details |
| YZJ-5053 | YZJ5053; YZJ-5053 | Phase 1 Clinical | Shanghai Haiyan Pharmaceutical Technology Co Ltd | Solid tumours; Neoplasm Metastasis | Details |
| Etrumadenant | AB-928; GS-0928 | Phase 2 Clinical | Arcus Biosciences Inc | Prostatic Neoplasms; Melanoma; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Carcinoma, Pancreatic Ductal; Laryngeal Neoplasms; Mouth Neoplasms; Pharyngeal Neoplasms; Lung Neoplasms; Carcinoma, Squamous Cell; Colorectal Neoplasms; Oropharyngeal Neoplasms; Breast Neoplasms; Ovarian Neoplasms; Urinary Bladder Neoplasms; Prostatic Neoplasms, Castration-Resistant; Triple Negative Breast Neoplasms; Carcinoma, Transitional Cell; Hypopharyngeal Neoplasms; Esophageal Neoplasms; Carcinoma, Renal Cell; Carcinoma, Merkel Cell; Rectal Neoplasms; Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Head and Neck Neoplasms | Details |
| Sodium Citrate/Citric Acid/Dextrose/Monosodium phosphate/Adenine | Details | ||||
| SHR-5126 | SHR-5126 | Phase 1 Clinical | Jiangsu Hengrui Medicine Co Ltd | Neoplasms | Details |
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