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Your Position: > CD79A

CD79A

요약

Name:B-cell antigen receptor complex-associated protein alpha chain
Target Synonym:Ig-alpha,MB-1 membrane glycoprotein,Membrane-bound immunoglobulin-associated protein,Surface IgM-associated protein
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

제품 리스트 구매

제품 상태별:
제품 유형별 :
태그별:
결합물별:
제품번호 제품 설명 구조 순도 특징
CDA-C52H3 Cynomolgus Cynomolgus CD79A Protein, His Tag
CDA-C52H3-structure
CDA-C52H3-sds
CDA-H52H8 Human Human CD79A Protein, His Tag
CDA-H52H8-structure
CDA-H52H8-sds

Synonym Name

CD79A, CD79a, B-cell antigen receptor complex-associated protein alpha chain, B-cell antigen receptor complex-associated protein alpha chain, Ig-alpha, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein,  Surface IgM-associated p

Background

B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain(CD79a), also known as CD79α, IgM-α, Ig-α and mb-1, which is a signaling component of the preB cell receptor (preBCR). Covalently linked CD79a and CD79b heterodimer constitutes the B cell antigen receptor (BCR) with membrane immunoglobulin (mIg) in a non-covalent association. CD79a is required in cooperation with CD79b for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR), leading to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79a is also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells.

Clinical and Translational Updates

임상 약품 정보

Name Research Code Research Phase Company Indications Clinical Trials
bbT-369 bbT-369 Phase 2 Clinical Bluebird Bio Inc Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin Details

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