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Cadherin-10

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CA0-H52H5 Human Human Cadherin-10 / CDH10 Protein, His Tag
CA0-H52H5-structure
CA0-H52H5-sds

Synonym Name

Cadherin-10,CDH10,T2-cadherin

Background

Cadherins are a large family of cell –cell adhesion molecules involved in inter-cellular adhesion in a wide variety of cell types. In the nervous system, cadherins are known to be crucial to all stages of development, including the early separation of the neural tube from the ectoderm, the segregation of neurones and axons, and the formation of synapses. These molecules mediate calcium ion-dependent, homotypic primers designed using two highly conserved amino acid sequences in the cytoplasmic domain. One of the cadherins identified was cadherin-10. Cadherin-10 was first partially cloned from human brain, but its mRNA has also been shown to be present in mouse thymus (designated T2-cadherin), mouse testis, and in the developing brain and eye of mouse, rat, and chick.

Clinical and Translational Updates

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