TLR2

Toll-like receptors (TLRs) take key roles in the host immune response and are swiftly activated by infection or other types of immunological stress. Toll-like receptor 2 (TLR2) is indicated to initiate the activation of NLRP3 inflammasome and might involve in asthma. Additionally, further research uncovered that Wnt5a is also a direct ligand of toll-like receptor (TLR) 2 and 4 might affect the typical pattern recognition receptor-induced innate immune response genes.