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Name:L-amino-acid oxidase Target Synonym:LAAO,LAO,Interleukin-4-induced protein 1,IL4-induced protein 1,hIL4I1,Protein Fig-1,hFIG1
Number of Launched Drugs:0 Number of Drugs in Clinical Trials:0 Lastest Research Phase:Preclinical
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Synonym Name
L-amino-acid oxidase,Interleukin 4 induced protein 1, IL4I1
Background
Interleukin-4-induced-1 (IL4I1) is s a key immunoregulator and acts as a negative regulator of anti-tumor immunity. IL4I1 could activate the Aryl hydrocarbon receptor (AHR) via the generation of indole metabolites and kynurenic acid. AHR associates with reduced survival in glioma patients, promotes cancer cell motility, and suppresses.
Clinical and Translational Updates
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