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Expression analysis of human PTK7 on HEK293/Human PTK7 Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human PTK7 Stable Cell Line or negative control cell using anti-human PTK7 antibody followed by fixation with 4% paraformaldehyde, and then stained with PE anti-human IgG Fc antibody.
Immobilized Cynomolgus / Rhesus macaque PTK7, His Tag (Cat. No. PT7-C52H3) at 1 μg/mL (100 μL/well) can bind Cofetuzumab Pelidotin with a linear range of 0.06-2 ng/mL (Routinely tested).
The purity of Mouse PTK7 Protein, Fc Tag (Cat. No. PT7-M5256) is more than 90% and the molecular weight of this protein is around 240-270 kDa verified by SEC-MALS.
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
PRO-1107 | PRO-1107 | Phase 2 Clinical | ProfoundBio (Suzhou) Co Ltd | Solid tumours; Ovarian Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Triple Negative Breast Neoplasms; Carcinoma, Transitional Cell; Endometrial Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
Cofetuzumab Pelidotin | PF-06647020; PF-6647020; PTK7-ADC; PF-06523435; PF-7020; hu-24; ABBV-647; Anti-PTK7 ADC; h6M24-vc0101 | Phase 1 Clinical | Abbvie Inc, Stemcentrx Inc | Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
PRO-1107 | PRO-1107 | Phase 2 Clinical | ProfoundBio (Suzhou) Co Ltd | Solid tumours; Ovarian Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Triple Negative Breast Neoplasms; Carcinoma, Transitional Cell; Endometrial Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
Cofetuzumab Pelidotin | PF-06647020; PF-6647020; PTK7-ADC; PF-06523435; PF-7020; hu-24; ABBV-647; Anti-PTK7 ADC; h6M24-vc0101 | Phase 1 Clinical | Abbvie Inc, Stemcentrx Inc | Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
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