로그인 회원가입
icon_bulk_order대량 주문 Acrobiosystems for English
Promotion
Recombinant Proteins ClearClear history
Recombinant Proteins CloseClose
Browse Products By Molecule Name a-zA-Z
TL1A Hot |GMP IL-2 Hot |Claudin 18.2 Hot |FMC 63 Ab  |FcRn
0
장바구니가 비어 있습니다
내 장바구니
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: 홈 > LIV-1

LIV-1

요약

Name:Zinc transporter ZIP6
Target Synonym:LIV-1,LIV1,LIV-1 Protein, Estrogen Regulated,Solute Carrier Family 39 (Metal Ion Transporter), Member 6,Zrt- and Irt-like protein 6,SLC39A6,Estrogen-regulated protein LIV-1,ZIP-6,Zinc transporter ZIP6,Solute Carrier Family 39 (Zinc Transporter), Member 6,Solute carrier family 39 member 6
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase 2 Clinical

Antibody Licensing

Project Name Project Stage Molecule Type Host Species Therapeutic Area Indications
LIV-1 mAb - 01 PCC Solid Tumor Colorectal cancer,Breast cancer

제품 리스트 구매

제품> 결과 필터링
제품 상태별:
제품 유형별 :
종별:
태그별:
결합물별:
제품번호 종 제품 설명 구조 순도 특징
LV1-H52P3 Human Human LIV-1 Full Length Protein (VLP)
LV1-R52H8 Rhesus macaque Rhesus macaque LIV-1 / SLC39A6 Protein, His Tag
LV1-R52H8-structure
LV1-R52H8-sds
LV1-M5253 Mouse Mouse LIV-1 / SLC39A6 Protein, Fc Tag (MALS verified)
LV1-M5253-structure
LV1-M5253-sds
LV1-H82F5 Human Biotinylated Human LIV-1 / SLC39A6 Protein, Fc,Avitag™ (MALS verified)
LV1-H82F5-structure
LV1-H82F5-sds
LV1-H5257 Human Human LIV-1 / SLC39A6 (229-325) Protein, Fc Tag (MALS verified)
LV1-H5257-structure
LV1-H5257-sds
LV1-M52H4 Mouse Mouse LIV-1 / SLC39A6 (C153A, C300A) Protein, His Tag (MALS verified)
LV1-M52H4-structure
LV1-M52H4-sds
LV1-H5255 Human Human LIV-1 / SLC39A6 Protein, Fc Tag, low endotoxin
LV1-H5255-structure
LV1-H5255-sds
LV1-C52H6 Cynomolgus Cynomolgus LIV-1 / SLC39A6 Protein, His Tag, low endotoxin
LV1-C52H6-structure
LV1-C52H6-sds
LV1-R52H9 Rat Rat LIV-1 / SLC39A6 Protein, His Tag
LV1-R52H9-structure
LV1-R52H9-sds
LV1-C82E5 Cynomolgus Biotinylated Cynomolgus LIV-1 / SLC39A6 Protein, His,Avitag™
LV1-C82E5-structure
LV1-C82E5-sds
LV1-C52H5 Cynomolgus Cynomolgus LIV-1 / SLC39A6 Protein, His Tag
LV1-C52H5-structure
LV1-C52H5-sds
LV1-H82E3 Human Biotinylated Human LIV-1 / SLC39A6 Protein, His,Avitag™
LV1-H82E3-structure
LV1-H82E3-sds
LV1-H5223 Human Human LIV-1 / SLC39A6 Protein, His Tag
LV1-H5223-structure
LV1-H5223-sds
LV1-H5254 Human Human LIV-1 / SLC39A6 Protein, Fc Tag (MALS verified)
LV1-H5254-structure
LV1-H5254-sds

일부의 생물활성 데이터

LV1-H5223-SPR
Human_FcRn_Heterodimer_Protein_SPR

Anti-LIV-1 mAb captured on CM5 chip via anti-human IgG Fc antibody can bind Human LIV-1, His Tag (Cat. No. LV1-H5223) with an affinity constant of 5.24 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

Protocol
LV1-H5254-SPR
LIV-1 SPR

Anti-LIV-1 mAb immobilized on CM5 can bind Human LIV-1, Fc Tag (Cat. No. LV1-H5254) with an affinity constant of 1.74 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

Protocol

사용자 리뷰

Synonym Name

SLC39A6,LIV-1,ZIP6,Zinc transporter ZIP6,ZIP-6

Background

LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines.

Clinical and Translational Updates

임상 약품 정보

Name Research Code Research Phase Company Indications Clinical Trials
Ladiratuzumab vedotin SGN-LIV1A; MK-6440; MK6440 Phase 2 Clinical Seagen Inc, Merck Sharp & Dohme Corp Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Esophageal Neoplasms; Small Cell Lung Carcinoma; Triple Negative Breast Neoplasms; Prostatic Neoplasms; Breast Neoplasms; Esophageal Squamous Cell Carcinoma; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Melanoma Details
BRY-812 BRY-812 Phase 1 Clinical BioRay Pharmaceutical Co Ltd Solid tumours; Neoplasms Details

This web search service is supported by Google Inc.

totop
Call us
우리에게 전화하세요
글로벌: +1 800-810-0816 (무료)
아시아태평양: +86 400-682-2521
Email
이메일
order.kr@acrobiosystems.com
Fax
팩스
+1 888-377-6111
Address
주소
서울 성동구 왕십리로10길 6 서울숲비즈포레 703
회사명
아크로바이오 주식회사
사업자 등록번호
186-88-02858
대표자
CHEN YIDING
사업장주소
서울특별시 송파구 중대로12길 10-20, 1층 셀렉티드송파(가락동)
linkedin twitter facebook youtube

문의

Copyright © 2017 ACROBiosystems. All Rights Reserved
Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap