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RNF43

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RN3-H5256 Human Human RNF43 Protein, Fc Tag (MALS verified)
RN3-H5256-structure
RN3-H5256-sds

일부의 생물활성 데이터

RN3-H5256-MALS-HPLC
Human RNF43, Fc Tag (Cat. No. ) MALS images

The purity of Human RNF43, Fc Tag (Cat. No. RN3-H5256) is more than 85% and the molecular weight of this protein is around 100-115 kDa verified by SEC-MALS.

Bioactivity-ELISA
Human RNF43, Fc TagHuman RNF43, Fc Tag (Cat. No. RN3-H5256) ELISA bioactivity

Immobilized Human R-Spondin 1, His Tag (Cat. No. RS1-H4221) at 5 μg/mL (100 μL/well) can bind Human RNF43, Fc Tag (Cat. No. RN3-H5256) with a linear range of 2-20 ng/mL (QC tested).

RN3-H5256-ELISA
Human RNF43, Fc TagHuman RNF43, Fc Tag (Cat. No. RN3-H5256) ELISA bioactivity

Immobilized Human R-Spondin 1, His Tag (Cat. No. RS1-H4221) at 5 μg/mL (100 μL/well) can bind Human RNF43, Fc Tag (Cat. No. RN3-H5256) with a linear range of 2-20 ng/mL (QC tested).

Synonym Name

RING finger protein 43,RING-type E3 ubiquitin transferase RNF43

Background

E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification (By similarity)

Clinical and Translational Updates

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