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Your Position: 홈 > TSHR

TSHR

요약

Name:Thyroid stimulating hormone receptor
Target Synonym:TSHR,Thyroid Stimulating Hormone Receptor,LGR3,Thyroid-Stimulating Hormone Receptor,Seven Transmembrane Helix Receptor,Thyrotropin Receptor-I, HTSHR-I,Thyrotropin Receptor,TSH Receptor,HTSHR-I,TSH-R,Receptors, Thyrotropin,CHNG1
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:3
Lastest Research Phase:Approved

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CHEK-ATP086 Human HEK293/Human TSHR Stable Cell Line
SCCHO-ATP085 Human CHO/Human TSHR Stable Cell Line Development Service

일부의 생물활성 데이터

CHEK-ATP086-Cell-based assay
TSHR FACS

Expression analysis of human TSHR on HEK293/Human TSHR Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human TSHR Stable Cell Line or negative control cell using anti-human TSHR Antibody followed by staining with PE anti-human IgG Fc Antibody.

Protocol
SCCHO-ATP085-Cell-based assay
TSHR FACS

Expression analysis of human TSHR on CHO/Human TSHR Stable Cell Line by FACS.
Cell surface staining was performed on CHO/Human TSHR Stable Cell Line or negative control cell using anti-human TSHR Antibody followed by staining with PE anti-human IgG Fc Antibody.

Protocol

Synonym Name

TSHR,TSH-R,LGR3,TSH R

Background

Thyroid-stimulating hormone receptor (TSHR) is also known as Thyrotropin receptor and LGR3. TSHR is glycosylated receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

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