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3C (HRV)

요약

Name:Picornain 3C protease
Target Synonym:D2C-3A-VPg(3B)-3C-D3D,Submitted name: Protease 3C
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Preclinical

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3CC-N3133 N/A HRV-3C Protease Cleavage Enzyme, GST Tag (active enzyme)
3CC-N3133-sds

Synonym Name

HRV-3C Protease,3C Protease

Background

Protease Recombinant is fusion protein of GST and human rhinovirus (HRV) type 14 3C protease.Substrate recognition and cleavage are likely to be dependent not only upon primary structural signals, but also upon the secondary and tertiary structures of the fusion protein as It has been demonstrated that the enzyme exhibits highest activity around neutral pH at temperature ranging from 22 to 37℃, even retaining robust activity at 4℃. Thus, cleavage can be performed at low temperature to enhance the stability of the target protein. The catalytic activity is insensitive to organic solvents (up to 10%); however, it can be strongly stimulated by high concentration of anions such as sulfate.

Clinical and Translational Updates

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