Human Transferrin R / CD71 Protein, Tag Free, low endotoxin (MALS verified)

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제품 번호/규격
가격
수량
TFR-H5213-100ug
$415.00
TFR-H5213-1mg (200ug X 5)
$2845.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    CD71, TFRC, TFR, sTfR, TfR1, Trfr, T9, p90

  • Source

    Human Transferrin R Protein, Tag Free (TFR-H5213) is expressed from human 293 cells (HEK293). It contains AA Cys 89 - Phe 760 (Accession # P02786-1).

    Predicted N-terminus: Cys 89

    Request for sequence
  • Molecular Characterization

    Transferrin R Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries no "tag".

    The protein has a calculated MW of 75.2 kDa. The protein migrates as 90-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

    The protein is designed as a dimer.

  • Endotoxin

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • SDS-PAGE

    Transferrin R SDS-PAGE

    Human Transferrin R Protein, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    Transferrin R SEC-MALS

    The purity of Human Transferrin R Protein, Tag Free (Cat. No. TFR-H5213) is more than 95% and the molecular weight of this protein is around 135-180 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     Transferrin R ELISA

    Immobilized Human Transferrin R Protein, Tag Free (Cat. No. TFR-H5213) at 5 μg/mL (100 μL/well) can bind Biotinylated Human Transferrin Protein, His,Avitag (Cat. No. TRN-H82E3) with a linear range of 0.2-6 ng/mL (QC tested).

    Protocol
  • Bioactivity-SPR

     Transferrin R SPR

    Monoclonal Anti-CD71 Antibody, Mouse IgG1 (5B5) (Cat. No. CD1-MY2101) captured on CM5 chip via anti-mouse antibodies surface can bind Human Transferrin R Protein, Tag Free (Cat. No. TFR-H5213) with an affinity constant of 0.570 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

    Protocol

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배경 소개

CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    Transferrin receptor protein 1

  • 카테고리:

  • 상장 의약품 수:

    1 상세

  • 임상 의약품 수:

    15 상세

  • 최고 개발 단계:

    Approved

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  • 배경
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