언어 선택

DLL3

DLL3 분자 정보

영어 이름	Delta-like protein 3	시판 약물 수	1
임상 약물 수	30	표적 별명	Delta-Like Protein 3，Delta3，Delta-Like 3，Drosophila Delta Homolog 3，SCDO1，Delta-Like 3 (Drosophila)，DLL3，Delta (Drosophila)-Like 3，Delta Like Canonical Notch Ligand 3
최고 연구 개발 단계	Approved

영어 이름	Delta-like protein 3
표적 별명	Delta-Like Protein 3，Delta3，Delta-Like 3，Drosophila Delta Homolog 3，SCDO1，Delta-Like 3 (Drosophila)，DLL3，Delta (Drosophila)-Like 3，Delta Like Canonical Notch Ligand 3
시판 약물 수	1
임상 약물 수	30
최고 연구 개발 단계	Approved

DLL3 제품 목록

속성
Protein (26)Cell (2)Cell Grade Beads (1)Kits (1)Beads (1)
제품 라이브러리
온라인 (31)
종
Human (24)Cynomolgus (4)Rat (1)Rhesus macaque (1)Mouse (1)
태그
His Tag (19)- (6)His Tag & Avi Tag (2)Llama IgG Fc Tag (1)Fc Tag (1)Mouse IgG Fc Tag (2)
마커
Unconjugated (19)FITC Labeled (1)Biotin-labeled (3)PE Labeled (1)- (5)APC Labeled (1)AF647 Labeled (1)

제품 번호	종	발현 시스템	제품 설명
HOT AIDD‑Ready DL3-H52H4	Human	HEK293	Human DLL3 Protein, His Tag, low endotoxin (Mass Spec & MALS verified)
HOT AIDD‑Ready DL3-M52H9	Mouse	HEK293	Mouse DLL3 Protein, His Tag, low endotoxin (HPLC verified)
HOT AIDD‑Ready DL3-C52H3	Cynomolgus	HEK293	Cynomolgus DLL3 Protein, His Tag (MALS verified)
CEA-B049	Human	-	Human DLL3 ELISA Kit
CHEK-ATP090	Human	HEK293	HEK293/Human DLL3 Stable Cell Line
DL3-H5243	Human	HEK293	Human DLL3 Protein, His Tag (HPLC verified)
DL3-H5256	Human	HEK293	Human DLL3 (353-427) Protein, Mouse IgG2a Fc Tag, low endotoxin (MALS verified)
DL3-H5259	Human	HEK293	Human DLL3 (353-465) Protein, Mouse IgG2a Fc Tag, low endotoxin
DL3-H525a	Human	HEK293	Human DLL3 Protein, Llama IgG2b Fc Tag, low endotoxin
DL3-H525c	Human	HEK293	Human DLL3 (27-215) Protein, Fc Tag (MALS verified)

총 수량31

제품 문의

DLL3분자 배경

Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.

DLL3분자 별명

Delta3,delta-like 3 (Drosophila),delta-like protein 3,DLL3,Pudgy,SCDO1,SCDO1delta3

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Zocilurtatug pelitecan	ZL-1310; YL-212	Phase 3 Clinical	Zai Lab (Shanghai) Co Ltd	Small Cell Lung Carcinoma; Solid tumours	상세
Obrixtamig	BI-764532; OBT620	Phase 3 Clinical	C.H. Boehringer Sohn Ag & Co. Kg	Carcinoma, Neuroendocrine; Glioma; Neoplasms; Neuroendocrine Tumors; Small Cell Lung Carcinoma	상세
Alveltamig	ZG-006; ZG006	Phase 3 Clinical	Gensun Biopharma Inc, Suzhou Zelgen Biopharmaceuticals Co Ltd	Carcinoma, Neuroendocrine; Neoplasms; Prostatic Neoplasms; Small Cell Lung Carcinoma; Solid tumours	상세
89Zr-DFO-SC16.56	89Zr-DFO-SC16.56	Phase 2 Clinical	Memorial Sloan Kettering Cancer Center	Small Cell Lung Carcinoma	상세
Gocatamig	HPN-328; MK-6070; DS-3280	Phase 2 Clinical	Harpoon Therapeutics	Carcinoma, Neuroendocrine; Small Cell Lung Carcinoma	상세
EB-DART-NK01	EB-DART-NK01	Phase 2 Clinical	Beijing Biotech	Small Cell Lung Carcinoma	상세
4sCAR-DLL3 CAR-T Therapy (Shenzhen Geno-Immune Medical Institute)		Phase 2 Clinical	Shenzhen Geno-Immune Medical Institute	Glioblastoma; Melanoma	상세
SHR-7787	SHR-7787; SHR7787	Phase 2 Clinical	Shanghai Hengrui Pharmaceutical Co Ltd	Small Cell Lung Carcinoma; Solid tumours	상세
SHR-4849	SHR-4849; SHR4849; IDE849; IDE-849	Phase 2 Clinical	Jiangsu Hengrui Pharmaceutical Group Co Ltd	Carcinoma, Neuroendocrine; Small Cell Lung Carcinoma; Solid tumours	상세
DLL3-CAR-NK cells Therapy(Tianjin Medical University Cancer Institute and Hospital)	DLL3-CAR-NK cells	Phase 2 Clinical	Tianjin Medical University Cancer Institute And Hospital	Small Cell Lung Carcinoma	상세
Peluntamig	PT-217	Phase 2 Clinical	Phanes Therapeutics Inc	Carcinoma, Neuroendocrine; Neuroendocrine Carcinoma of Lung; Prostatic Neoplasms; Small Cell Lung Carcinoma; Solid tumours	상세
ML-261	ML261; ML-261	Phase 1 Clinical	Moonlight Bio Inc	Carcinoma, Neuroendocrine; Gastroenteropancreatic neuroendocrine tumor; Prostatic Neoplasms; Small Cell Lung Carcinoma	상세
NEUK203-13	NEUK203-13	Phase 1 Clinical	Neukio Biotherapeutics (Shanghai) Co Ltd	Neuroendocrine Tumors; Small Cell Lung Carcinoma	상세
111In-ABD147		Phase 1 Clinical	Abdera Therapeutics Inc	Neuroendocrine Tumors; Prostatic Neoplasms, Castration-Resistant; Solid tumours	상세
111In-ETN029	111In-ETN029	Phase 1 Clinical	Novartis Pharma Ag	Gastroenteropancreatic neuroendocrine tumor; Neuroendocrine Tumors; Prostatic Neoplasms; Small Cell Lung Carcinoma	상세
225Ac-ETN029	225Ac-ETN029; [225Ac]Ac-ETN029	Phase 1 Clinical	Novartis Pharma Ag	Gastroenteropancreatic neuroendocrine tumor; Neuroendocrine Tumors; Prostatic Neoplasms; Small Cell Lung Carcinoma	상세
HLX-3901	HLX-3901	Phase 1 Clinical	Shanghai Henlius Biotech Inc	Carcinoma, Neuroendocrine; Neoplasm Metastasis; Small Cell Lung Carcinoma; Solid tumours	상세
177Lu-DTPA-SC16.56	177Lu-DTPA-SC16.56	Phase 1 Clinical	Memorial Sloan Kettering Cancer Center	Carcinoma, Neuroendocrine; Lung Neoplasms; Neuroendocrine Carcinoma of Lung; Prostatic Neoplasms	상세
SYS-6040	SYS6040; SYS-6040	Phase 1 Clinical	Jushi Biopharmaceutical Co Ltd	Neoplasms; Neuroendocrine Tumors; Small Cell Lung Carcinoma; Solid tumours	상세
IBI-3009	IBI3009; IBI-3009	Phase 1 Clinical		Carcinoma, Neuroendocrine; Small Cell Lung Carcinoma; Solid tumours	상세
BL-M14D1	BL-M14D1	Phase 1 Clinical	Baili-Bio (Chengdu) Pharmaceutical Co Ltd, Sichuan Baili Pharmaceutical Co Ltd	Carcinoma, Neuroendocrine; Neuroendocrine Tumors; Small Cell Lung Carcinoma; Solid tumours	상세
BHP-01	BHP-01; BHP01; α-PD-L1/4-1BB DLL3 CAR-T	Phase 1 Clinical	Chengdu Brilliant Pharmaceutical Co Ltd	Small Cell Lung Carcinoma	상세
FZ-AD005	FZ-AD005; FZAD005; F0041	Phase 1 Clinical	Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd	Carcinoma, Neuroendocrine; Glioblastoma; Glioma; Small Cell Lung Carcinoma; Solid tumours	상세
[89Zr]Zr-BI-764532		Phase 1 Clinical	Boehringer Ingelheim International Gmbh, C.H. Boehringer Sohn Ag & Co. Kg	Carcinoma, Neuroendocrine; Small Cell Lung Carcinoma	상세
ABD-147	ABD-147; 225Ac-ABD147	Phase 1 Clinical	Abdera Therapeutics Inc	Neuroendocrine Tumors; Small Cell Lung Carcinoma; Solid tumours	상세
SNC-115	SNC115; SNC-115	Phase 1 Clinical	Shanghai Simnova Biotechnology Co Ltd	Carcinoma, Neuroendocrine; Small Cell Lung Carcinoma; Solid tumours	상세
RG-6524	RO-7616789; ALPS-12; RG6524	Phase 1 Clinical	F. Hoffmann-La Roche Ag	Carcinoma, Neuroendocrine; Small Cell Lung Carcinoma	상세
OBT620	OBT620	Phase 1 Clinical	Boehringer Ingelheim Gmbh, Oxford Biotherapeutics Ltd	Small Cell Lung Carcinoma	상세
QLS-31904	QLS-31904; QLS31904	Phase 1 Clinical	Qilu Pharmaceutical Co Ltd	Solid tumours	상세
LB-2102(Legend Biotechnology)	LB-2102	Phase 1 Clinical		Neuroendocrine Tumors; Small Cell Lung Carcinoma	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Tarlatamab	AMG-757	Approved	Amgen Inc	Imdelltra	United States	Small Cell Lung Carcinoma	Amgen Inc	2024-05-16	Astrocytoma; Brain metastases; Carcinoma, Merkel Cell; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Ganglioglioma; Glioblastoma; Medullary thyroid cancer (MTC); Melanoma; Neoplasms; Neuroendocrine Tumors; Oligodendroglioma; Paranasal Sinus Diseases; Prostatic Neoplasms; Small Cell Lung Carcinoma; Testicular Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms	상세