Biotinylated Cynomolgus DLL3 Protein, His,Avitag™ (SPR verified)

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DL3-C82E9-25ug
$415.00
In Stock - Delivery in 2-3 business days
DL3-C82E9-200ug
$1880.00
In Stock - Delivery in 2 weeks
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    Delta3, delta-like 3 (Drosophila), delta-like protein 3, DLL3, Pudgy, SCDO1, SCDO1delta3

  • Source

    Biotinylated Cynomolgus DLL3, His,Avitag (DL3-C82E9) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Arg 488 (Accession # A0A2K5WSR1-1).

    Predicted N-terminus: Ala 27

    Request for sequence
  • Molecular Characterization

    DLL3 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 51.7 kDa. The protein migrates as 47-52 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Labeling

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • Protein Ratio

    Passed as determined by the SABA assay / HABA assay / binding ELISA.

  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • SDS-PAGE

    DLL3 SDS-PAGE

    Biotinylated Cynomolgus DLL3, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • Bioactivity-ELISA

     DLL3 ELISA

    Immobilized Biotinylated Cynomolgus DLL3, His,Avitag (Cat. No. DL3-C82E9) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Anti-DLL3 Antibody (specific Binding DSL of DLL3), Human IgG1 with a linear range of 0.1-1 ng/mL (Routinely tested).

    Protocol
  •  DLL3 ELISA

    Immobilized Biotinylated Cynomolgus DLL3, His,Avitag (Cat. No. DL3-C82E9) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Anti-DLL3 Antibody (specific Binding EGFs of DLL3), Human IgG1 with a linear range of 0.2-2 ng/mL (Routinely tested).

    Protocol
  • Bioactivity-SPR

     DLL3 SPR

    Anti-DLL3 Antibody (specific Binding DSL of DLL3), Human IgG1 captured on Protein A Chip can bind Biotinylated Cynomolgus DLL3, His,Avitag (Cat. No. DL3-C82E9) with an affinity constant of 3.61 nM as determined in a SPR assay (Biacore 8K) (QC tested).

    Protocol

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배경 소개

Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    Delta-like protein 3

  • 카테고리:

  • 상장 의약품 수:

    1 상세

  • 임상 의약품 수:

    28 상세

  • 최고 개발 단계:

    Approved

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  • 고객님도 확인한 상품
  • 데이터 표시
  • 사용자 리뷰
  • 배경
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