Human Tau-381 / 1N3R Protein, Tag Free, low endotoxin (MALS verified)

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제품 번호/규격
가격
수량
TAU-H5112-100ug
$280.00
TAU-H5112-1mg
$1860.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    DDPAC, FTDP-17, MAPT, MSTD, MTBT1, Tau, PHF-tau, TAU

  • Source

    Human Tau-381 / 1N3R Protein, Tag Free (TAU-H5112) is expressed from E. coli cells. It contains AA Met 1 - Leu 381 (Accession # P10636-4).

    Predicted N-terminus: Met 1

    Request for sequence
  • Molecular Characterization

    Tau Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries no "tag".

    The protein has a calculated MW of 39.7 kDa. The protein migrates as 43-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

  • Endotoxin

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Supplied as 0.2 μm filtered solution in 20 mM Tris, 150 mM NaCl, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • SDS-PAGE

    Tau SDS-PAGE

    Human Tau-381 / 1N3R Protein, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    Tau SEC-MALS

    The purity of Human Tau-381 / 1N3R Protein, Tag Free (Cat. No. TAU-H5112) is more than 95% and the molecular weight of this protein is around 30-50 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     Tau ELISA

    Immobilized Human Tau-381 / 1N3R Protein, Tag Free (Cat. No. TAU-H5112) at 1 μg/mL (100 μL/well) can bind Tau Monoclonal Antibody with a linear range of 0.1-2 ng/mL (QC tested).

    Protocol

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배경 소개

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    Microtubule-associated protein tau

  • 카테고리:

  • 상장 의약품 수:

    1 상세

  • 임상 의약품 수:

    46 상세

  • 최고 개발 단계:

    Approved

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  • 배경
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