Hantaan virus (Orthohantavirus andesense) pre-Gc Protein, His Tag

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Cat. No. / Size
Price
Qty
PRN-V52H3-50ug
$ 465.00
PRN-V52H3-100ug
$ 785.00
PRN-V52H3-1mg
$ 2885.00

Product Details

  • Synonyms

    pre-Gc protein

  • Source

    Hantaan virus (Orthohantavirus andesense) pre-Gc Protein, His Tag (PRN-V52H3) is expressed from human 293 cells (HEK293). It contains AA Glu 652 - Asn 1107 (Accession # Q9E006).

    Predicted N-terminus: Glu 652

  • Molecular Characterization

    pre-Gc protein Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 51.8 kDa.

  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Background

Hantaviruses (genus Orthohantavirus) are enveloped, negative-sense, single-stranded ribonucleic acid (R) viruses. The genomes of hantaviruses are composed of tri-segmented single-stranded, negative sense R, designated as small (S), medium (M) and large (L) segments. Each segment encodes nucleocapsid protein (NP), glycoprotein precursor (GPC) and R-dependent R polymerase (RdRp), respectively. GPC is posttranslationally cleaved into Gn and Gc. Glycoproteins Gn and Gc are transmembrane proteins and constitute an envelope with a lipid membrane derived from host cells. Gn and Gc are involved in receptor binding, membrane fusion and induction of protective immunity. The two glycoproteins are presumed to be the major elements involved in the induction of neutralizing antibodies during hantavirus infection.

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