Human NKp44 / NCR2 / CD336 Protein, Llama IgG2b Fc Tag, low endotoxin

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제품 번호/규격
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NC2-H5258-100ug
$390.00
NC2-H5258-1mg (250ug X 4)
$2575.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    Natural cytotoxicity triggering receptor 2, NKp44, NCR2, CD336, LY95

  • Source

    Human NKp44, Llama IgG2b Fc Tag (NC2-H5258) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Ala 192 (Accession # O95944-1).

    Predicted N-terminus: Gln 22

    Request for sequence
  • Molecular Characterization

    NKp44 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a llama IgG2b Fc tag at the C-terminus.

    The protein has a calculated MW of 46.5 kDa. The protein migrates as 55-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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데이터 표시

  • SDS-PAGE

    NKp44 SDS-PAGE

    Human NKp44, Llama IgG2b Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • Bioactivity-ELISA

     NKp44 ELISA

    Immobilized PDGF-DD Protein, Human at 5 μg/mL (100 μL/well) can bind Human NKp44, Llama IgG2b Fc Tag (Cat. No. NC2-H5258) with a linear range of 0.008-0.25 μg/mL (Routinely tested).

    Protocol

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배경 소개

NKp44, a member of Natural Cytotoxicity Receptors (NCRs), is an activating receptor playing a crucial role in most functions exerted by activated NK cells and also by other NKp44+ immune cells. Membrane-associated PCNA is a ligand for the NKp44 (NCR2) innate immune receptorMembrane-associated PCNA is a ligand for the NKp44 (NCR2) innate immune receptor. NKp44 / NCR2 / CD336 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    Natural cytotoxicity triggering receptor 2

  • 카테고리:

  • 상장 의약품 수:

    0 상세

  • 임상 의약품 수:

    0 상세

  • 최고 개발 단계:

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