Product Details
Synonyms
MAdCAM-1, MAdCAM1, Mucosal vascular addressin cell adhesion molecule 1 transcript variant 1
Source
Cynomolgus MAdCAM-1 Protein, His Tag (MAM-C52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Lys 291 (Accession # XP_045235080.1).
Predicted N-terminus: Gln 22
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 30.5 kDa. The protein migrates as 33-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 0.01 EU per μg by the LAL method / rFC method.
Purity
>90% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Performance Data
SDS-PAGE

Cynomolgus MAdCAM-1 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).
Bioactivity-ELISA

Immobilized Cynomolgus MAdCAM-1 Protein, His Tag (Cat. No. MAM-C52H3) at 5 μg/mL (100 μL/well) can bind Biotinylated Human ITGA4&ITGB7 Heterodimer Protein, His,Avitag&Tag Free (Cat. No. IT7-H82W4) with a linear range of 0.02-0.313 μg/mL (QC tested).
Protocol
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Background
Recent Advances
- English Name:
Mucosal addressin cell adhesion molecule-1
- Category:
- Approved Drugs:
1 Details
- Drugs in Clinical Trials:
4 Details
- Highest Development Stage:
Approved
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