PE-Labeled Human HLA-A*24:02&B2M&Survivin-2B (AYACNTSTL) Tetramer Protein

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HLN-HP2H6-25ug
$410.00
HLN-HP2H6-200ug (100ug X 2)
$2350.00
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제품 세부정보

  • Synonyms

    HLA-A*2402 & B2M & Survivin-2B (AYACNTSTL)

  • Source

    PE-Labeled Human HLA-A*24:02&B2M&Survivin-2B (AYACNTSTL) Tetramer Protein (HLN-HP2H6) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*24:02) & Ile 21 - Met 119 (B2M) & AYACNTSTL peptide (Accession # AAA59600.1 (HLA-A*24:02) & P61769 (B2M) & AYACNTSTL).

    Predicted N-terminus: Gly 25 & Ala

    Request for sequence
  • Molecular Characterization

    PE-Labeled Human HLA-A*24:02&B2M&Survivin-2B (AYACNTSTL) Tetramer Protein is assembled by biotinylated monomer (HLN-H82E3) and PE-labeled streptavidin.

    Biotinylated Human HLA-A*24:02&B2M&Survivin-2B (AYACNTSTL) Complex Protein is produced by co-expression of HLA and B2M loaded with Survivin-2B peptide. Biotinylated Human HLA-A*24:02&B2M&Survivin-2B (AYACNTSTL) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, 1% BSA, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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배경 소개

Survivin, also known as BIRC5 and EPR-1, is a member of the inhibitor of apoptosis (IAP) family, which encodes negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but birc5 encodes proteins with only a single BIR domain. The Human HLA-A*2402 Survivin-2B (AYACNTSTL) complex protein is a complex of HLA-A*2402 of the MHC Class I, B2M and AYACNTSTL peptide of the Survivin-2B.

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