HSV-1 (strain 17) Envelope Glycoprotein D (gD), His Tag (MALS verified)

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GLD-V52H3-50ug
$305.00
GLD-V52H3-500ug
$1545.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    Glycoprotein D/gD (HSV)

  • Source

    HSV-1 (strain 17) Envelope Glycoprotein D (gD), His Tag (GLD-V52H3) is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Thr 310 (Accession # Q69091-1).

    Predicted N-terminus: Lys 26

    Request for sequence
  • Molecular Characterization

    Glycoprotein D/gD (HSV) Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 33.5 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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데이터 표시

  • SDS-PAGE

    Glycoprotein D/gD (HSV) SDS-PAGE

    HSV-1 (strain 17) Envelope Glycoprotein D (gD), His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • SEC-MALS

    Glycoprotein D/gD (HSV) SEC-MALS

    The purity of HSV-1 (strain 17) Envelope Glycoprotein D (gD), His Tag (Cat. No. GLD-V52H3) is more than 85% and the molecular weight of this protein is around 33-50 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     Glycoprotein D/gD (HSV) ELISA

    Immobilized HSV-1 (strain 17) Envelope Glycoprotein D (gD), His Tag (Cat. No. GLD-V52H3) at 5 μg/mL (100 μL/well) can bind Human Nectin-1, Fc Tag (Cat. No. PV1-H5253) with a linear range of 0.3-5 ng/mL (QC tested).

    Protocol
  •  Glycoprotein D/gD (HSV) ELISA

    Immobilized Human Nectin-1, Fc Tag (Cat. No. PV1-H5253) at 5 μg/mL (100 μL/well) can bind HSV-1 (strain 17) Envelope Glycoprotein D (gD), His Tag (Cat. No. GLD-V52H3) with a linear range of 0.01-0.313 μg/mL (Routinely tested).

    Protocol

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배경 소개

Herpes simplex virus type 1 (HSV‑1) glycoprotein D (gD) is an essential envelope protein required for viral entry. By binding host receptors such as nectin‑1, gD triggers the membrane‑fusion cascade that allows HSV‑1 to penetrate cells. Neutralizing antibodies targeting gD can block receptor engagement and inhibit infection.

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