Mouse FCRL5 Protein, His Tag, low Endotoxin (MALS verified)

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Cat. No. / Size
Price
Qty
FC5-M52H3-100ug
$360.00
FC5-M52H3-1mg (500ug X 2)
$2380.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    BXMAS1, CD307, CD307e, FCRH5, IRTA2, PRO820

  • Source

    Mouse FCRL5 Protein, His Tag (FC5-M52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 27 - Ala 496 (Accession # NP_899045).

    Predicted N-terminus: Gln 27

    Request for sequence
  • Molecular Characterization

    FCRL5 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 54.5 kDa. The protein migrates as 65-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    FCRL5 SDS-PAGE

    Mouse FCRL5 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    FCRL5 SEC-MALS

    The purity of Mouse FCRL5 Protein, His Tag (Cat. No. FC5-M52H3) is more than 90% and the molecular weight of this protein is around 55-75 kDa verified by SEC-MALS.

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Background

Fc Receptor-Like 5 (FCRL5), also known as FcRH3 (FcRH5 in human), IRTA2, and CD307e, is a 90 ‑ 95 kDa member of the FCRL family of proteins whose amino acid (aa) sequence is reminiscent of that for classical Fc receptors. FCLR molecules are type 1 transmembrane proteins that contain from three to nine immunoglobulin-like domains. They are differentially expressed within the B cell lineage, and can either promote or inhibit B cell proliferation and activation

Recent Advances

 
Drug Development Progress
  • English Name:

    Fc receptor-like protein 5

  • Category:

  • Approved Drugs:

    0 Details

  • Drugs in Clinical Trials:

    3 Details

  • Highest Development Stage:

    Phase 2 Clinical

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