Human DLL3 (176-492) Protein, His Tag, low endotoxin (MALS & SPR verified)

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제품 번호/규격
가격
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DL3-H52Hy-100ug
$395.00
DL3-H52Hy-1mg
$2500.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    Delta3, delta-like 3 (Drosophila), delta-like protein 3, DLL3, Pudgy, SCDO1, SCDO1delta3

  • Source

    Human DLL3 (176-492) , His Tag (DL3-H52Hy) is expressed from human 293 cells (HEK293). It contains AA Ala 176 - Leu 492 (Accession # Q9NYJ7-1).

    Predicted N-terminus: Ala 176

    Request for sequence
  • Molecular Characterization

    DLL3 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 34.4 kDa. The protein migrates as 38-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, pH7.4.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • SDS-PAGE

    DLL3 SDS-PAGE

    Human DLL3 (176-492) , His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • SEC-MALS

    DLL3 SEC-MALS

    The purity of Human DLL3 (176-492) , His Tag (Cat. No. DL3-H52Hy) is more than 90% and the molecular weight of this protein is around 35-55 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     DLL3 ELISA

    Immobilized Human DLL3 (176-492) , His Tag (Cat. No. DL3-H52Hy) at 1 μg/mL (100 μL/well) can bind Anti-DLL3 Antibody (specific Binding DSL of DLL3), Human IgG1 with a linear range of 0.1-2 ng/mL (Routinely tested).

    Protocol
  •  DLL3 ELISA

    Immobilized Human DLL3 (176-492) , His Tag (Cat. No. DL3-H52Hy) at 1 μg/mL (100 μL/well) can bind Anti-DLL3 Antibody (specific Binding EGFs of DLL3), Human IgG1 with a linear range of 0.1-2 ng/mL (Routinely tested).

    Protocol
  • Bioactivity-SPR

     DLL3 SPR

    Anti-DLL3 Antibody (specific Binding DSL of DLL3), Human IgG1 captured on Protein A Chip can bind Human DLL3 (176-492) , His Tag (Cat. No. DL3-H52Hy) with an affinity constant of 1.04 nM as determined in a SPR assay (Biacore 8K) (QC tested).

    Protocol

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배경 소개

Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    Delta-like protein 3

  • 카테고리:

  • 상장 의약품 수:

    1 상세

  • 임상 의약품 수:

    28 상세

  • 최고 개발 단계:

    Approved

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  • 제품 세부정보
  • 고객님도 확인한 상품
  • 데이터 표시
  • 사용자 리뷰
  • 배경
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