Alexa Fluor™ 647-Labeled Human CD8 alpha Protein, His TagStar Staining

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제품 번호/규격
가격
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CDA-HA2H5-25ug
$450.00
CDA-HA2H5-200ug
$2803.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    CD8A, CD8, Leu2, MAL, p32

  • Source

    Alexa Fluor 647-Labeled Human CD8 alpha Protein, His Tag (CDA-HA2H5) is produced via conjugation of AF647 to Human CD8 alpha Protein, His Tag with a new generation site-specific technology under Star Staining labeling platform. Human CD8 alpha Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Ser 22 - Asp 182 (Accession # P01732-1).

    Predicted N-terminus: Ser 22

  • Molecular Characterization

    This protein carries a polyhistidine tag at the C-terminus.

  • Conjugate

    AF647

    Excitation Wavelength: 640 nm

    Emission Wavelength: 672 nm

  • Protein Ratio

    The AF647 to protein molar ratio is 0.8-1.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • Bioactivity-FACS

     CD8 alpha FACS

    1e5 of Mouse Anti-CD8 antibody coupled beads (5.5 μm) were stained with different concentration of Alexa Fluor 647-Labeled Human CD8 alpha Protein, His Tag (Cat. No. CDA-HA2H5) and negative control protein respectively, AF647 signal was used to evaluate the binding activity (QC tested).

    Protocol
  •  CD8 alpha FACS

    1e5 of Mouse Anti-CD8 antibody coupled beads (5.5 μm) were stained with different concentration of Alexa Fluor 647-Labeled Human CD8 alpha Protein, His Tag (Cat. No. CDA-HA2H5) and negative control protein respectively, AF647 signal was used to evaluate the binding activity (QC tested).

    Protocol

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배경 소개

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    Cluster of differentiation 8

  • 카테고리:

  • 상장 의약품 수:

    0 상세

  • 임상 의약품 수:

    18 상세

  • 최고 개발 단계:

    Phase 3 Clinical

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