Canine BCMA / TNFRSF17 Protein, His Tag (MALS verified)

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제품 번호/규격
가격
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BCA-C52H3-100ug
$360.00
BCA-C52H3-1mg
$2615.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonyms

    TNFRSF17, CD269, BCM, BCMA

  • Source

    Canine BCMA, His Tag (BCA-C52H3) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Asn 44 (Accession # A0A8C0N4C4).

    Request for sequence
  • Molecular Characterization

    BCMA Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 7.1 kDa. The protein migrates as 10-12 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • SDS-PAGE

    BCMA SDS-PAGE

    Canine BCMA, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • SEC-MALS

    BCMA SEC-MALS

    The purity of Canine BCMA, His Tag (Cat. No. BCA-C52H3) is more than 85% and the molecular weight of this protein is around 7-12 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     BCMA ELISA

    Immobilized Canine BCMA, His Tag (Cat. No. BCA-C52H3) at 5 μg/mL (100 μL/well) can bind Human BAFF, Fc Tag, active trimer (Cat. No. BAF-H5261) with a linear range of 0.2-2 ng/mL (QC tested).

    Protocol
  •  BCMA ELISA

    Immobilized Canine BCMA, His Tag (Cat. No. BCA-C52H3) at 5 μg/mL (100 μL/well) can bind Anti-BCMA Neutralizing Antibody, Mouse IgG1 (Cat. No. BCA-M43) with a linear range of 0.02-0.313 μg/mL (Routinely tested).

    Protocol
  •  BCMA ELISA

    Immobilized Human APRIL, Fc Tag at 5 μg/mL (100 μL/well) can bind Canine BCMA, His Tag (Cat. No. BCA-C52H3) with a linear range of 0.2-1 ng/mL (Routinely tested).

    Protocol

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배경 소개

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    B-cell maturation protein

  • 카테고리:

  • 상장 의약품 수:

    8 상세

  • 임상 의약품 수:

    145 상세

  • 최고 개발 단계:

    Approved

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  • 고객님도 확인한 상품
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  • 사용자 리뷰
  • 배경
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