Monoclonal Anti-Mumps virus Fusion glycoprotein F0 Antibody, Human IgG1 (5A3) (MALS verified)

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제품 번호/규격
가격
수량
RSF-MY2092-100ug
$415.00
RSF-MY2092-1mg (500ug X 2)
$2735.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Source

    Monoclonal Anti-Mumps virus Fusion glycoprotein F0 Antibody, Human IgG1 (5A3) is a chimeric monoclonal antibody recombinantly expressed in HEK293, which combines the variable region of a mouse monoclonal antibody with human constant domain.

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    5A3

  • Isotype

    Human IgG1, Kappa

  • Host Species

    Mouse

  • Reactivity

    Mumps virus (strain Miyahara vaccine) (MuV)

  • Immunogen

    Recombinant Mumps virus (strain Miyahara vaccine) (MuV) Fusion glycoprotein F0 is expressed from human 293 cells

  • Specificity

    Specifically recognizes Mumps virus Fusion glycoprotein F0 Protein.

  • Application

    Application
    Recommended Usage
    Western Blot
    10-0.02 ug/mL
  • Purification

    Protein A purified / Protein G purified.

  • Aggregation

    Less than 10%, as determined by SEC-MALS.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • Bioactivity-ELISA

     Fusion glycoprotein F0 ELISA

    Immobilized Mumps virus (strain Miyahara vaccine) (MuV) Fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H4) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Mumps virus Fusion glycoprotein F0 Antibody, Human IgG1 (5A3) (Cat. No. RSF-MY2092) with a linear range of 0.1-4 ng/mL (QC tested).

    Protocol
  • Western Blot

     Fusion glycoprotein F0 WESTERN BLOT
  • Detection of Monoclonal Anti-Mumps virus Fusion glycoprotein F0 antibody-5A3, Human IgG1 | Human Kappa ,HEK by Western Blot. Monoclonal Anti-Mumps virus Fusion glycoprotein F0 antibody-5A3, Human IgG1 | Human Kappa,HEK at 0.02ug/ml dilution + Mumps virus (strain Miyahara vaccine) (MuV) Fusion glycoprotein F0, His Tag (MALS verified), His Tag at 400ng.<br>
    Secondary Antibody: (HFC)-HRP Goat Anti-Human IgG,Fcγ fragment specific (min X Bov,Hrs,Ms Sr Prot) at 1/2000 dilution.<br>
    Predicted band size: 53-75 kDa 12% Bis-Tris Protein Gel.

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배경 소개

The two surface glycoproteins of the mumps virus are the hemagglutinin-neuraminidase (HN) and Fusion proteins. These glycoproteins are essential for viral entry to host cells, and the spread of newly formed virions. The mumps fusion protein (F) is a 538-amino acid, class one fusion surface glycoprotein. It is responsible for the membrane fusion of virus and host cell. The un-cleaved protein has three hydrophobic regions: an amino-terminal signal peptide, an amino terminal region of F1 and the carboxyl-terminal membrane domain. This protein starts as a precursor molecule (F0), and is then cleaved into the active protein by the recognition of a R-X-L/R-R motif by a host endoprotease (furin). The F protein contains two disulfide-linked polypeptides (F1 and F2).

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    Respiratory syncytial virus F protein

  • 카테고리:

  • 상장 의약품 수:

    3 상세

  • 임상 의약품 수:

    7 상세

  • 최고 개발 단계:

    Approved

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  • 고객님도 확인한 상품
  • 데이터 표시
  • 사용자 리뷰
  • 배경
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