PE-Labeled Monoclonal Anti-Human BTLA Antibody, Mouse IgG2a (AS616) (0.03% Proclin)

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Cat. No. / Size
Price
Qty
FABm036-01-200tests (50tests X 4)
$3400.00
ETA of in-stock products:2 business days

Product Details

  • Source

    Monoclonal Anti-Human BTLA Antibody, Mouse IgG2a (AS616) is a mouse monoclonal antibody, which provides higher batch consistency and long term security of supply.

  • Clone

    AS616

  • Isotype

    Mouse IgG2a, Kappa

  • Host Species

    Mouse

  • Reactivity

    Human

  • Immunogen

    Purified Human BTLA Protein

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Specificity

    This product is a specific antibody specifically reacts with BTLA protein.

  • Application

    Flow Cytometry (Evaluation of the expression of BTLA on Human cells).

  • Isotype Control

    The isotype control is sold separately; please refer to Cat. No. DNP-PM487 for product information.

  • Form

    Liquid

  • Formulation

    Supplied as 0.2 μm-filtered solution in PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA, with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Shipping

    Liquid product is shipped at blue ice.

  • Storage

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Bioactivity-FACS

     BTLA FACS

    Flow cytometric analysis of THP-1 staining with PE-Labeled Monoclonal Anti-Human BTLA Antibody, Mouse IgG2a (AS616) (Cat. No. FABm036-01) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 1e6 cells in afinal volume of 100 µL), compared with isotype control antibody. PE signal was used to evaluate the binding activity (QC tested).

    Protocol

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Background

B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.

Recent Advances

 
Drug Development Progress
  • English Name:

    B- and T-lymphocyte attenuator

  • Category:

  • Approved Drugs:

    0 Details

  • Drugs in Clinical Trials:

    6 Details

  • Highest Development Stage:

    Phase 3 Clinical

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