Human STEAP3 Full Length Protein (VLP)

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제품 번호/규격
가격
수량
ST3-H52P3-20ug
$620.00
ST3-H52P3-100ug
$1235.00
ST3-H52P3-500ug (250ug X 2)
$4305.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Application

    1. Immunization
    2. FACS
    3. Elisa
  • Synonym

    STEAP3

  • Source

    Human STEAP3 Full Length Protein (VLP) (ST3-H52P3) is expressed from human 293 cells (HEK293). It contains AA Pro 2 - Val 488 (Accession # Q658P3-1).

    Predicted N-terminus: Met

  • Molecular Characterization

    1. Structure

      Virus-like particles (VLPs) are protein particles that mimic the shape of viruses but lack a viral genome, and incorporating transmembrane proteins on the external surface.

    2. Synthesis Process

      Virus-like particles (VLPs) are non-infectious structures that mimic the shape of viruses but lack a viral genome. During VLP production in cells systems, VLPs self-assemble into 100-200 nm protein particles, and incorporate transmembrane proteins into a VLP-MP complex, resulting in presentation of the protein on the external surface of the VLP. Their repetitive, multivalent surface display and strong immunogenicity, making them an excellent candidate for immunization.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Formulation

    The VLPs are highly immunogenic, so the immunization strategy should be optimized (antigen dose, regimen and adjuvant).

    Supplied as 0.2 μm filtered solution in PBS, Arginine, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 12 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process
  • *The isotype control of empty/mock VLP (Cat. No. VLP-N5213) is sold separately and not included in protein, you can follow the link for product information.

고객님도 확인한 상품

데이터 표시

  • Identity-DLS

     STEAP3 DLS

    The mean peak Radius of VLP is 65-90 nm with more than 95% intensity as determined by dynamic light scattering (DLS).

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배경 소개

A metalloreductase primarily involved in endosomal iron reduction during transferrin-mediated iron uptake. STEAP3 expression is essential for erythroid maturation. It is also upregulated in various cancers, contributing to iron addiction and oxidative stress management, making it a potential therapeutic node in iron-dependent malignancies.

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