제품 수집
제품 세부정보
Synonym
PDCD1, PD1, CD279, SLEB2
Source
Human PD-1 Protein, Llama IgG2b Fc Tag (PD1-H5259) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Gln 167 (Accession # Q15116-1).
Predicted N-terminus: Leu 25
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a llama IgG2b Fc tag at the C-terminus.
The protein has a calculated MW of 43.8 kDa. The protein migrates as 55-75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 0.01 EU per μg by the LAL method / rFC method.
Purity
>95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Formulation
Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
고객님도 확인한 상품
데이터 표시
SDS-PAGE
Human PD-1 Protein, Llama IgG2b Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
SEC-MALS
The purity of Human PD-1 Protein, Llama IgG2b Fc Tag (Cat. No. PD1-H5259) is more than 90% and the molecular weight of this protein is around 90-115 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA
Immobilized Human PD-L1 Protein, Mouse IgG1 Fc Tag at 0.5 μg/mL (100 μL/well) can bind Human PD-1 Protein, Llama IgG2b Fc Tag (Cat. No. PD1-H5259) with a linear range of 0.02-0.31 μg/mL (QC tested).
Protocol
Immobilized Human PD-1 Protein, Llama IgG2b Fc Tag (Cat. No. PD1-H5259) at 2 μg/mL (100 μL/well) can bind Nivolumab with a linear range of 0.1-2 ng/mL (Routinely tested).
Protocol
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배경 소개
프론티어 진행
의약품 개발 진행- 영어 이름：
Programmed cell death protein 1
- 카테고리：
- 상장 의약품 수：
22 상세
- 임상 의약품 수：
193 상세
- 최고 개발 단계：
Approved
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전화
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