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APC-Labeled Monoclonal Anti-Human CD73 Antibody, Mouse IgG1 (5A10) (0.03% Proclin)

COADS MS
DS

사용자 리뷰
제품 번호/규격
가격
수량
FABm024-02-100tests (50tests X 2)
$220.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0
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제품 세부정보

  • Source

    Monoclonal Anti-Human CD73 Antibody, Mouse IgG1 (5A10) is a mouse monoclonal antibody recombinantly expressed from Hybridoma.

  • Application

    Flow Cytometry (Evaluation of the expression of CD73 on Human cells).

  • Clone

    5A10

  • Species

    Mouse

  • Isotype

    Mouse Fc

  • Specificity

    This product is a specific antibody specifically reacts with CD73 protein.

  • Reactivity

    Human

  • Immunogen

    Purified Human CD73 Protein

  • Conjugate

    APC

    Excitation Wavelength: 640 nm

    Emission Wavelength: 661 nm

  • Recommended Dilution

    1:20

  • Formulation

    Supplied as 0.2 μm-filtered solution in PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA, with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Storage

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.

  • Shipping

    This product is supplied and shipped with blue ice, please inquire the shipping cost.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • Bioactivity-FACS

    CD73 FACS

    Flow cytometric analysis of MSC staining with APC-Labeled Monoclonal Anti-Human CD73 Antibody, Mouse IgG1 (5A10) (Cat. No. FABm024-02) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 1e6 cells in a final volume of 100 µL), compared with isotype control antibody. APC signal was used to evaluate the binding activity (QC tested).

    Protocol

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배경 소개

5'-nucleotidase (5'-NT), also known as ecto-5'-nucleotidase or CD73 (cluster of differentiation 73), is an enzyme that is encoded by the NT5E gene. CD73 commonly serves to convert AMP to adenosine. Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. Rare allelic variants are associated with a syndrome of adult-onset calcification of joints and arteries (CALJA) affecting the iliac, femoral, and tibial arteries reducing circulation in the legs and the joints of the hands and feet causing pain.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름：

    5'-nucleotidase

  • 카테고리：

  • 상장 의약품 수：

    0 상세

  • 임상 의약품 수：

    36 상세

  • 최고 개발 단계：

    Phase 3 Clinical

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