Product Details
Background
Recombinant Monoclonal Anti-CD68 Antibody, Rabbit (2D8) is a CD68 primary antibody for IHC application. Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Product Specifications
Host SpeciesRabbitIsotypeIgGClone2D8ApplicationIHCProperty1:1000StateLiquidPositive ControlHuman Tonsil TissuesClonalityMonoclonalResearch FieldCancer Drug TargetsSourceRabbitSynonymDKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1Experiment Protocol
Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. The shelf life is 30 days from the date of opening.
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Performance Data
Control Sample

Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelled with HGS-S262 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Cancer Sample


Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S262 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
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