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PE-Labeled Monoclonal Anti-Human CD43 Antibody, Mouse IgG1 (AS672) (0.03% Proclin)

COADS MS
DS

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제품 번호/규격
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FABm065-01-200tests (50tests X 4)
$200.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0
신제품 제안
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제품 세부정보

  • Source

    Monoclonal Anti-Human CD43 Antibody, Mouse IgG1 (AS672) is a mouse monoclonal antibody, which provides higher batch consistency and long term security of supply.

  • Application

    Flow Cytometry (Evaluation of the expression of CD43 on Human cells).

  • Clone

    AS672

  • Species

    Mouse

  • Isotype

    Mouse IgG1 | Mouse Kappa

  • Specificity

    This product is a specific antibody specifically reacts with CD43 protein.

  • Reactivity

    Human

  • Immunogen

    Purified Human CD43 Protein

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Isotype Control

    The isotype control is sold separately; please refer to Cat. No. DNP-PM1 for product information.

  • Recommended Dilution

    1:20

  • Formulation

    Supplied as 0.2 μm-filtered solution in PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA, with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Storage

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.

  • Shipping

    This product is supplied and shipped with blue ice, please inquire the shipping cost.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • Bioactivity-FACS

    CD43 FACS

    Flow cytometric analysis of Human Jurkat cells staining with PE-Labeled Monoclonal Anti-Human CD43 Antibody, Mouse IgG1 (AS672) (Cat. No. FABm065-01) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 1e6 cells in a final volume of 100 µL), compared with isotype control antibody. PE signal was used to evaluate the binding activity (QC tested).

    Protocol

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배경 소개

CD43, also designated Ly-48, leukosialin, sialophorin, leukocyte sialoglycoprotein and W3/13, is a large type I transmembrane glycoprotein enriched with O-glycosylation and sialylation sites. It binds to CD54 (ICAM-1), CD62E, CD169 (Siglec-1), CD328 (Siglec-7) and MHC Class I molecules. Widely expressed on T lymphocytes, thymocytes, monocytes, granulocytes, bone marrow stem cells, pre-B cells, activated B cells and plasma cells—but absent on resting peripheral blood B cells, red blood cells and nonhematopoietic cells—CD43 modulates leukocyte functions (bidirectional adhesion, T cell costimulation, apoptosis induction) via intercellular interactions. Enzymatic shedding of activated leukocyte surface CD43 may exert negative regulation on adaptive immune responses, making it a valuable target for flow cytometry analysis.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름：

    Leukosialin

  • 카테고리：

  • 상장 의약품 수：

    0 상세

  • 임상 의약품 수：

    0 상세

  • 최고 개발 단계：

    Preclinical

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