Human CD2 / SRBC Protein, His Tag, low endotoxin (MALS verified)

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제품 번호/규격
가격
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CD2-H5226-50ug
$395.00
CD2-H5226-1mg (500ug X 2)
$2985.00
ETA of in-stock products:2 business days
총 항목 수 제품 금액$ 0

제품 세부정보

  • Synonym

    CD2, SRBC, LFA-2, T11

  • Source

    Human CD2, His Tag (CD2-H5226) is expressed from human 293 cells (HEK293). It contains AA Lys 25 - Asp 209 (Accession # AAH33583).

    Predicted N-terminus: Lys 25

    Request for sequence
  • Molecular Characterization

    CD2 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 22.3 kDa. The protein migrates as 33-40 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

고객님도 확인한 상품

데이터 표시

  • SDS-PAGE

    CD2 SDS-PAGE

    Human CD2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    CD2 SEC-MALS

    The purity of Human CD2, His Tag (Cat. No. CD2-H5226) is more than 95% and the molecular weight of this protein is around 23-35 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     CD2 ELISA

    Immobilized Human CD2, His Tag (Cat. No. CD2-H5226) at 10 μg/mL (100 μL/well) can bind Human CD58, Fc Tag (Cat. No. LF3-H5256) with a linear range of 0.04-0.31 ug/mL (QC tested).

    Protocol
  • Bioactivity-BLI

     CD2 BLI

    Loaded bind Human CD58, Fc Tag (Cat. No. LF3-H5256) on Protein A Biosensor, can bind Human CD2, His Tag (Cat. No. CD2-H5226) with an affinity constant of 0.49 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

    Protocol
  •  CD2 BLI

    Loaded bind Human CD58, Fc Tag (Cat. No. LF3-H5256) on AHC Biosensor, can bind Human CD2, His Tag (Cat. No. CD2-H5226) with an affinity constant of 0.57 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

    Protocol

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배경 소개

T-cell surface antigen CD2 is also known as Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5 and SRBC, is a single-pass type I membrane protein found on the surface of T cells and natural killer (NK) cells. CD2 is a member of the immunoglobulin superfamily. CD2 / SRBC contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CD2 / SRBC interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3 / CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. In addition to its adhesive properties, CD2 also acts as a co-stimulatory molecule on T and NK cells. CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections.

프론티어 진행

 
의약품 개발 진행
  • 영어 이름:

    T-cell surface antigen CD2

  • 카테고리:

  • 상장 의약품 수:

    0 상세

  • 임상 의약품 수:

    3 상세

  • 최고 개발 단계:

    Phase 2 Clinical

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