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TNF-alpha
TNF-alpha Overview
| English Name | Tumor necrosis factor α | Approved Drugs | 69 |
| Drugs in Clinical Trials | 60 | Target Synonym | ICD1，Tumor necrosis factor，Tumor Necrosis Factor (TNF Superfamily， Member 2)，Tumor Necrosis Factor Ligand 1F，Tumor Necrosis Factor-Alpha，TNF Superfamily， Member 2，TNF， Macrophage-Derived，TNF， Monocyte-Derived，APC1 Protein，TNLG1F，DIF，NTF，TNF-a，TNF-alpha，ICD2，N-terminal fragment，TNF，Tumor necrosis factor ligand superfamily member 2，Cachectin，TNFSF2，TNFA |
| Highest Development Stage | Approved | ||
| English Name | Tumor necrosis factor α |
| Target Synonym | ICD1，Tumor necrosis factor，Tumor Necrosis Factor (TNF Superfamily， Member 2)，Tumor Necrosis Factor Ligand 1F，Tumor Necrosis Factor-Alpha，TNF Superfamily， Member 2，TNF， Macrophage-Derived，TNF， Monocyte-Derived，APC1 Protein，TNLG1F，DIF，NTF，TNF-a，TNF-alpha，ICD2，N-terminal fragment，TNF，Tumor necrosis factor ligand superfamily member 2，Cachectin，TNFSF2，TNFA |
| Approved Drugs | 69 |
| Drugs in Clinical Trials | 60 |
| Highest Development Stage | Approved |
TNF-alpha Product List
- Product Category
Protein (17)Kits (11)Antibody (4)Cell (1)
- Product Status
Launched (33)
- Species
Human (19)Mouse (9)Canine (1)Cynomolgus (2)Rat (1)Rabbit (1)
- Tag
Tag Free (5)His Tag & Avi Tag (3)His Tag (6)- (16)Fc Tag (2)Fc Tag & Avi Tag (1)
- Conjugate
Unconjugated (15)Biotin-labeled (6)- (12)
Total: 33
- 1
- 2
- 3
- 4
TNF-alpha Background
Tumor necrosis factor alpha (TNFα) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFα is in the regulation of immune cells. TNFα is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFα production has been implicated in a variety of human diseases, including major depression, Alzheimers disease and cancer. Recombinant TNFα is used as an immunostimulant under the INN tasonermin. TNFα can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.
TNF-alpha Synonyms
DIF,TNF-alpha,TNFA,TNFSF2,cachexin,cachectin,TNFα
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Adalimumab biosimilar (Danhong Pharma) | BC-002 | Phase 3 Clinical | Shandong Danhong Pharmaceutical Co Ltd | Arthritis, Rheumatoid; Spondylitis, Ankylosing | Details |
| Adalimumab biosimilar (Hetero Drugs) | Phase 3 Clinical | Hetero Drugs Ltd | Arthritis, Rheumatoid | Details | |
| Efprezimod alfa | CD24-Fc; HAS-CD24; CD24-Fc-IgG; MK-7110; MK7110 | Phase 3 Clinical | Oncoimmune Inc | Coronavirus Disease 2019 (COVID-19); Dyslipidemias; Graft vs Host Disease; Hematopoietic stem cell transplantation (HSCT); HIV Infections; Leukemia; Leukemia, Myeloid, Acute; Melanoma; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Solid tumours | Details |
| Adalimumab biosimilar (CinnaGen) | Phase 3 Clinical | Cinnagen | Arthritis, Rheumatoid | Details | |
| Etanercept biosimilar (Clover Biopharmaceuticals) | SCB-808 | Phase 3 Clinical | Clover Biopharmaceuticals Ltd | Arthritis, Rheumatoid; Spondylitis, Ankylosing; Thrombocytopenia | Details |
| SFA-002 | SFA-002; SFA002 | Phase 3 Clinical | SFA Therapeutics Inc | Arthritis, Rheumatoid; Plaque psoriasis; Psoriasis | Details |
| Adalimumab biosimilar (Oncobiologics) | Onco-3010; HOT-3010; ONS-3010 | Phase 3 Clinical | Outlook Therapeutics Inc | Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Crohn Disease; Pediatric Crohn's disease; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing; Uveitis | Details |
| Recombinant anti-TNFα monoclonal antibody (Wuhan Institute of Biological Products) | Phase 3 Clinical | Wuhan Institute Of Biological Products Co Ltd | Plaque psoriasis | Details | |
| Adalimumab biosimilar (Tonghua Dongbao Pharmaceutical) | Phase 3 Clinical | Tonghua Dongbao Pharmaceutical Co Ltd | Arthritis, Rheumatoid; Plaque psoriasis | Details | |
| Adalimumab biosimilar (Enzene Biosciences) | Phase 3 Clinical | Enzene Biosciences Ltd | Spondylitis, Ankylosing | Details | |
| Golimumab biosimilar (Reliance Life Sciences) | RTPR-044 | Phase 3 Clinical | Reliance Life Sciences | Arthritis, Rheumatoid | Details |
| Tanfanercept | HL-036; HBM-9036; HL-189; HL-036337 | Phase 3 Clinical | Hanall | Xerophthalmia | Details |
| 99mTc Certolizumab | Phase 3 Clinical | Universitair Ziekenhuis Gent | Axial Spondyloarthritis | Details | |
| Adalimumab biosimilar (Trpharm) | Phase 3 Clinical | Trpharm | Arthritis, Rheumatoid | Details | |
| Etanercept Biosimilar (Mabxience Holdings) | MB04; MB-04 | Phase 3 Clinical | Mabxience Holdings SL | Arthritis, Rheumatoid; Autoimmune Diseases | Details |
| Adalimumab biosimilar (Mabscale) | Phase 3 Clinical | Mabscale LLC | Plaque psoriasis | Details | |
| Adalimumab biosimilar(Incepta) | Phase 3 Clinical | Incepta Pharmaceuticals Ltd | Arthritis, Rheumatoid | Details | |
| Hemay007 | Hemay-007 | Phase 2 Clinical | Tianjin Hemay Bio-Tech Co Ltd | Arthritis, Rheumatoid; Colitis, Ulcerative; Inflammatory Bowel Diseases | Details |
| Recombinant anti-TNFα monoclonal antibody (Livzon Group) | AT-132(Livzon Group); LZM-001 | Phase 2 Clinical | Livzon Pharmaceutical Group Inc | Arthritis, Rheumatoid | Details |
| CC-10015 | CC-10015 | Phase 2 Clinical | Celgene Corp | Lupus Erythematosus, Systemic; Multiple Myeloma; Sarcoidosis | Details |
| EYS-606 | EYS-606 | Phase 2 Clinical | Eyevensys SAS | Uveitis | Details |
| Dovramilast | CC-11050; AMG-634 | Phase 2 Clinical | Celgene Corp | HIV Infections; Leprosy; Lupus Erythematosus, Cutaneous; Tuberculosis | Details |
| Licaminlimab | OCS-02; ESBA-1622; LME-636 | Phase 2 Clinical | Alcon, Oculis Pharma | Dry Eye Syndromes; Uveitis, Anterior; Xerophthalmia | Details |
| XTMAB-16 | XTMAB-16 | Phase 2 Clinical | Xentria Inc | Sarcoidosis, Pulmonary | Details |
| SOR-101 | SOR-101; SOR101 | Phase 2 Clinical | Sorriso Pharmaceuticals Inc | Colitis | Details |
| IMB-101 (IMBiologics) | IMB-101 (IMBiologics); HDM-3019; IMB101 (IMBiologics); HDM3019; NAV-240 | Phase 2 Clinical | IMBiologics Corp | Arthritis, Rheumatoid; Hidradenitis Suppurativa | Details |
| Balinatunfib | SAR-441566; SAR441566 | Phase 2 Clinical | Sanofi | Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis; Psoriasis | Details |
| Brivekimig | SAR-442970; SAR442970 | Phase 2 Clinical | Sanofi | Colitis, Ulcerative; Crohn Disease; Diabetes Mellitus, Type 1; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Hidradenitis Suppurativa; Inflammation; Nephrosis | Details |
| Guselkumab/Golimumab | JNJ-78934804 | Phase 2 Clinical | Janssen Research & Development Llc | Colitis, Ulcerative; Crohn Disease | Details |
| Isomyosamine | MYMD-1 | Phase 2 Clinical | Mymd Pharmaceuticals Inc | Anxiety; Arthritis, Rheumatoid; Coronavirus Disease 2019 (COVID-19); Depression; Frailty; Hashimoto Disease; Healthy Aging; Inflammation; Sarcopenia | Details |
| ME-3183 | ME-3183 | Phase 2 Clinical | Meiji Seika Pharmatech Co Ltd | Plaque psoriasis; Psoriasis | Details |
| Igrelimogene litadenorepvec | PM-1016; PM1016; TILT-123 | Phase 2 Clinical | Tilt Biotherapeutics Ltd | Carcinoma, Hepatocellular; Fallopian Tube Neoplasms; Lung Neoplasms; Melanoma; Ovarian Neoplasms; Peritoneal Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck | Details |
| Recombinant human anti-TNFα monoclonal antibody (Qilu Pharmaceutical) | Phase 1 Clinical | Qilu Pharmaceutical Co Ltd | Arthritis, Rheumatoid; Spondylitis, Ankylosing | Details | |
| Recombinant human monoclonal antibody specific for human tumor necrosis factor (North China Pharmaceutical) | Phase 1 Clinical | North China Pharmaceutical Company Ltd | Arthritis, Rheumatoid; Psoriasis; Spondylitis, Ankylosing | Details | |
| Certolizumab (Intrexon) | AG-014 | Phase 1 Clinical | Intrexon Corporation | Inflammatory Bowel Diseases | Details |
| Adalimumab biosimilar (Weimingdamu Biotech) | Phase 1 Clinical | Anhui Weiming Damu Biomedicine Co Ltd | Arthritis, Rheumatoid | Details | |
| Anti-tumour necrosis factor alpha (Livzon) | Phase 1 Clinical | Livzon Pharmaceutical Group Inc | Autoimmune Diseases | Details | |
| Etanercept biosimilar (Suzhou Genemen Biotech) | BF-02; GM-02 | Phase 1 Clinical | Suzhou Genemen Biotech Co Ltd | Spondylitis, Ankylosing | Details |
| Infliximab biosimilar (Ospedale San Raffaele) | Phase 1 Clinical | Ospedale San Raffaele | Takayasu Arteritis | Details | |
| Recombinant anti-TNFα antibody (Shanghai Xiesheng Medicine) | Phase 1 Clinical | Shanghai Harmony Pharmaceutical Technology Co Ltd | Details | ||
| JNJ-61178104 | JNJ-61178104 | Phase 1 Clinical | Johnson & Johnson Innovative Medicine | Autoimmune Diseases | Details |
| Adalimumab biobetter (Xencor/Zenas Biopharma) | Xtend-TNF; XmAb-6755; ZB-002 | Phase 1 Clinical | Xencor Inc | Arthritis, Rheumatoid; Autoimmune Diseases of the Nervous System | Details |
| JNJ-63823539 | JNJ-63823539 | Phase 1 Clinical | Johnson & Johnson Innovative Medicine | Arthritis, Rheumatoid | Details |
| Etanercept biosimilar (Shilpa Biologicals) | SBDM-01 | Phase 1 Clinical | Shilpa Biologicals Pvt Ltd | Arthritis, Psoriatic; Arthritis, Rheumatoid; Plaque psoriasis; Polyarticular Juvenile Idiopathic Arthritis; Spondylitis, Ankylosing | Details |
| KYS-202004-A | KYS202004A; KYS-202004-A | Phase 1 Clinical | Jiangsu Kanion Pharmaceutical Co Ltd | Psoriasis | Details |
| Adalimumab biosimilar (Laboratorios Richmond) | Phase 1 Clinical | Laboratorios Richmond | Details | ||
| KD-6005 | KD-6005; KD6005 | Phase 1 Clinical | Shanghai Celgen Bio-Pharmaceutical Co Ltd, Shanghai Kanda Bio-Technology Co Ltd | Arthritis, Rheumatoid | Details |
| NEX-20A | NEX-20A | Phase 1 Clinical | Nanexa AB | Multiple Myeloma | Details |
| IA-14069 | IA-14069 | Phase 1 Clinical | ILAb Co Ltd | Arthritis, Rheumatoid | Details |
| SOR-102 | SOR-102 | Phase 1 Clinical | Sorriso Pharmaceuticals Inc | Colitis, Ulcerative; Inflammatory Bowel Diseases | Details |
| Monoclonal Antibody (Mab) sB24M | Phase 1 Clinical | Swiss Biopharma Med GmbH | Pyoderma; Pyoderma Gangrenosum | Details | |
| ND-009 | ND-009 | Phase 1 Clinical | Numab Therapeutics Ag, Tillotts Pharma Ag | Inflammation | Details |
| Adalimumab biosimilar (DZM Biotech) | Phase 1 Clinical | Dzm Biotech Ltd | Arthritis, Rheumatoid | Details | |
| Adalimumab biosimilar (Prestige BioPharma) | PBP-1502 | Phase 1 Clinical | Prestige BioPharma Ltd | Details | |
| Adalimumab biosimilar (AXXO) | Clinical | Axxo | Arthritis, Psoriatic; Arthritis, Rheumatoid | Details | |
| IBPM005IX (Inbiopro Solutions) | Clinical | Inbiopro Solutions | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Crohn Disease; Spondylitis, Ankylosing | Details | |
| Etanercept (Neurokine Pharmaceuticals) | NP-1; NK-001 | Clinical | Pivot Pharmaceuticals | Cognition Disorders | Details |
| Etanercept biosimilar (Bio Sidus S.A) | Clinical | Biosidus | Arthritis, Rheumatoid; Autoimmune Diseases | Details | |
| Adalimumab biosimilar(BioXpress) | BX-2922; BXT-2922 | Clinical | Bioxpress Therapeutics Sa | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Hidradenitis Suppurativa; Pediatric Crohn's disease; Spondylitis, Ankylosing; Uveitis | Details |
| Wogonin | China Pharmaceutical University, Daewoong Pharmaceutical Co Ltd, Hefei Cosource Medicine Technology, Shandong Buchang Pharmaceuticals Co Ltd | Details |
Marketed Drug Information
| English Name | Research Code | Highest Development Stage | Company | Earliest Brand Name | Earliest Approval Country | Earliest Indication | Earliest Approval Company | Earliest Approval Date | Indication | Clinical Trial |
|---|---|---|---|---|---|---|---|---|---|---|
| Etanercept biosimilar (Hanwha Chemical) | HD-203; MK-8953 | Approved | Hanwha Chemical | Davictrel | Arthritis, Psoriatic; Arthritis, Rheumatoid; Psoriasis; Spondylitis, Ankylosing | Details | ||||
| Anti-tumour necrosis factor-alpha antibody | Approved | Materia Medica Holding Research And Production Company | Artrofoon, Arthrofoon | Arthritis, Rheumatoid; Osteoarthritis | Details | |||||
| Etanercept biosimilar (AryoGen Biopharma) | Approved | Aryogen Biopharma | Altebrel | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Psoriasis; Spondylitis, Ankylosing | Details | |||||
| Adalimumab biosimilar (Reliance Life Sciences) | R-TPR-021 | Approved | Reliance Life Sciences | Adfrar IB | India | Colitis, Ulcerative; Psoriasis; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid | Torrent Pharma, Reliance Life Sciences | 2016-01-12 | Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Psoriasis; Spondylitis, Ankylosing | Details |
| Certolizumab pegol | PHA-738144; CDP-870; CZP | Approved | Ucb | 希敏佳, Cimzia, Cimziat | United States | Crohn Disease | Ucb Inc | 2008-04-22 | Arthritis, Psoriatic; Arthritis, Rheumatoid; Axial Spondyloarthritis; Colitis, Ulcerative; Crohn Disease; Cystitis, Interstitial; Erythrodermic psoriasis; Generalised pustular psoriasis; Guttate Psoriasis; Infertility, Male; Non-radiographic axial spondyloarthritis; Osteoarthritis, Spine; Palmoplantar pustulosis; Plaque psoriasis; Polyarticular Juvenile Idiopathic Arthritis; Psoriasis; Spondylarthropathies; Spondylitis, Ankylosing | Details |
| Etanercept biosimilar (Nanogen Biopharmaceutical) | Approved | Nanogen Biopharmaceutical Co | Nanercept | Vietnam | Psoriasis; Arthritis, Rheumatoid | Nanogen Biopharmaceutical Co | 2019-01-01 | Arthritis, Rheumatoid; Psoriasis | Details | |
| Infliximab Biosimilar (Genor Biopharma) | GB-242 | Approved | Genor Biopharma Co Ltd | 佳佑健 | Mainland China | Spondylitis, Ankylosing; Crohn Disease; Psoriasis; Colitis, Ulcerative; Arthritis, Rheumatoid | Yuxi Genor Biotechnology Co Ltd | 2022-02-23 | Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis; Spondylitis, Ankylosing | Details |
| Etanercept biosimilar (Mochida) | LBEC-0101 | Approved | Mochda Pharmaceutical Co Ltd | Japan | Arthritis, Juvenile; Arthritis, Rheumatoid | null | 2018-01-19 | Arthritis, Juvenile; Arthritis, Rheumatoid | Details | |
| Adalimumab biosimilar (Amgen) | ABP-501 | Approved | Amgen Inc | Amjevita, Amgevita, Solymbic | United States | Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis | Amgen Inc | 2016-09-23 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Behcet Syndrome; Colitis, Ulcerative; Crohn Disease; Hidradenitis Suppurativa; Non-radiographic axial spondyloarthritis; Pediatric Crohn's disease; Pediatric ulcerative colitis; Plaque psoriasis; Polyarticular Juvenile Idiopathic Arthritis; Psoriasis; Spondylitis, Ankylosing; Uveitis | Details |
| Etanercept biosimilar (PROBIOMED) | Approved | Probiomed | Infinitam | Mexico | Arthritis, Rheumatoid | Probiomed | 2014-01-01 | Arthritis, Rheumatoid | Details | |
| Adalimumab biosimilar (Fresenius Kabi) | MSB-11022 | Approved | Fresenius Kabi Ag, Merck Serono | Idacio, Kromeya | EU | Crohn Disease; Spondylitis, Ankylosing; Hidradenitis Suppurativa; Psoriasis | Fresenius Kabi Deutschland Gmbh | 2019-04-02 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Hidradenitis Suppurativa; Pediatric Crohn's disease; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing; Uveitis | Details |
| Etanercept biosimilar (Sandoz) | GP-2015 | Approved | Clariant Produkte (Schweiz) Ag | Erelzi | United States | Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Psoriasis | Sandoz | 2016-08-30 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing | Details |
| Adalimumab biosimilar (Sinocelltech) | SCT-630 | Approved | SinoCelltech Ltd | 安佳润 | Mainland China | Psoriasis; Arthritis, Juvenile; Uveitis; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Crohn Disease; Pediatric Crohn's disease | SinoCelltech Ltd | 2023-06-07 | Arthritis, Juvenile; Arthritis, Rheumatoid; Crohn Disease; Pediatric Crohn's disease; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing; Uveitis | Details |
| Etanercept biosimilar (Amega Biotech) | Approved | Amega Biotech | Enerceptan | Argentina | Arthritis, Rheumatoid | Amega Biotech | 2012-01-01 | Arthritis, Rheumatoid | Details | |
| Infliximab biosimilar (Reliance Life Sciences) | BOW-015; R-TPR-015 | Approved | Epirus Biopharmaceuticals Inc | Infimab | Arthritis, Rheumatoid | Details | ||||
| Adalimumab biosimilar (Celltrion) | CT-P17 | Approved | Celltrion Inc | Yuflyma | EU | Hidradenitis Suppurativa; Crohn Disease; Colitis, Ulcerative; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Psoriatic; Psoriasis; Plaque psoriasis; Pediatric Crohn's disease; Arthritis, Juvenile; Pediatric ulcerative colitis; Uveitis | Celltrion Healthcare Hungary Kft | 2021-02-11 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Behcet Syndrome; Colitis, Ulcerative; Crohn Disease; Hidradenitis Suppurativa; Pediatric Crohn's disease; Pediatric ulcerative colitis; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing; Uveitis | Details |
| Etanercept biosimilar (Intas Biopharmaceuticals) | Approved | Intas Biopharmaceuticals | Intacept | India | Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Psoriasis | Intas Biopharmaceuticals | 2015-03-01 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Psoriasis; Spondylitis, Ankylosing | Details | |
| Infliximab biosimilar (Amgen) | ABP-710 | Approved | Amgen Inc | Avsola | United States | Pediatric ulcerative colitis; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Plaque psoriasis; Colitis, Ulcerative; Crohn Disease; Pediatric Crohn's disease | Amgen Inc | 2019-12-06 | Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Pediatric Crohn's disease; Pediatric ulcerative colitis; Plaque psoriasis; Spondylitis, Ankylosing | Details |
| Adalimumab biosimilar (Lg Chemical) | LBAL | Approved | Lg Chemical Ltd | Xelenka | Japan | Panuveitis; Colitis, Ulcerative; Crohn Disease; Spondylitis, Ankylosing; Behcet Syndrome; Uveitis, Intermediate; Uveitis, Posterior; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic; Arthritis, Juvenile | Mochda Pharmaceutical Co Ltd | 2021-03-23 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Behcet Syndrome; Colitis, Ulcerative; Crohn Disease; Hidradenitis Suppurativa; Non-radiographic axial spondyloarthritis; Panuveitis; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing; Uveitis; Uveitis, Intermediate; Uveitis, Posterior | Details |
| Adalimumab biosimilar (Boehringer Ingelheim) | BI-695501 | Approved | C.H. Boehringer Sohn Ag & Co. Kg | Cyltezo | United States | Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis | Boehringer Ingelheim International Gmbh | 2017-08-25 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Hidradenitis Suppurativa; Psoriasis; Spondylitis, Ankylosing; Uveitis | Details |
| Golimumab | CNTO-148; rTNV148B | Approved | Johnson & Johnson Innovative Medicine | Simponi/Simponi aria, Simponi, Simponi aria | United States | Spondylitis, Ankylosing; Arthritis, Psoriatic; Arthritis, Rheumatoid | Centocor Ortho Biotech Inc | 2009-04-24 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Axial Spondyloarthritis; Colitis, Ulcerative; Crohn Disease; Diabetes Mellitus, Type 1; Labyrinth Diseases; Non-radiographic axial spondyloarthritis; Pediatric ulcerative colitis; Spondylitis, Ankylosing | Details |
| Adalimumab biosimilar (Mylan/Biocon) | BMO-2; MYL-1401-A | Approved | Biocon Ltd | United States | Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis | Mylan Pharmaceuticals Inc | 2020-07-06 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Hidradenitis Suppurativa; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing | Details | |
| Golimumab biosimilar (Bio-thera) | BAT-2506; Bat2506 | Approved | Bio-Thera Solutions Ltd | Gotenfia | EU | Arthritis, Psoriatic; Axial Spondyloarthritis; Colitis, Ulcerative; Arthritis, Rheumatoid; Arthritis, Juvenile | Stada Arzneimittel Ag | 2026-02-10 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Axial Spondyloarthritis; Colitis, Ulcerative; Spondylitis, Ankylosing | Details |
| Luminol sodium | MP-1032 | Approved | Metrio, Selvim | Psoriasis; Immune System Diseases | null | 1997-01-01 | Coronavirus Disease 2019 (COVID-19); Immune System Diseases; Plaque psoriasis; Psoriasis | Details | ||
| Adalimumab biosimilar (Innovent Biologics) | IBI-303 | Approved | 苏立信 | Mainland China | Psoriasis; Spondylitis, Ankylosing; Arthritis, Rheumatoid | Innovent Biologics(Suzhou) Co Ltd | 2020-09-02 | Arthritis, Juvenile; Arthritis, Rheumatoid; Crohn Disease; Pediatric Crohn's disease; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing; Uveitis | Details | |
| Infliximab biosimilar (Pfizer) | PF-6438179; GP-1111; PF-06438179 | Approved | Pfizer Inc | Ixifi, Zessly | EU | Spondylitis, Ankylosing; Arthritis, Rheumatoid; Pediatric Crohn's disease; Pediatric ulcerative colitis; Colitis, Ulcerative; Crohn Disease; Psoriasis; Arthritis, Psoriatic | Pfizer Europe Ma Eeig | 2013-09-09 | Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Pediatric Crohn's disease; Pediatric ulcerative colitis; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing | Details |
| Adalimumab biosimilar (Bio-Thera Solutions) | BAT-1406 | Approved | Bio-Thera Solutions Ltd | 格乐立 | Mainland China | Arthritis, Rheumatoid; Crohn Disease; Uveitis; Spondylitis, Ankylosing; Psoriasis | Bio-Thera Solutions Ltd | 2019-11-04 | Arthritis, Rheumatoid; Crohn Disease; Psoriasis; Spondylitis, Ankylosing; Uveitis | Details |
| Etanercept biosimilar (AXXO) | TNF-a-Fc | Approved | Axxo | Russian Federation | Arthritis, Rheumatoid | Axxo | 2013-01-01 | Arthritis, Rheumatoid | Details | |
| Adalimumab biosimilar (Alvotech) | AVT-02 (Alvotech) | Approved | Alvotech hf | SIMLANDI, Ardalicip, Ciptunec, HUKYNDRA, LIBMYRIS | EU | Uveitis; Hidradenitis Suppurativa; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Crohn Disease; Psoriasis; Colitis, Ulcerative | Stada Arzneimittel Ag | 2021-11-12 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis; Colitis, Ulcerative; Crohn Disease; Hidradenitis Suppurativa; Inflammation; Non-radiographic axial spondyloarthritis; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing; Uveitis | Details |
| Adalimumab biosimilar (Biocad) | BCD-057 | Approved | BIOCAD JSC | Russian Federation | Psoriasis | BIOCAD JSC | 2019-03-01 | Psoriasis | Details | |
| Adalimumab biosimilar (Shanghai Henlius Biotech) | HLX-03 | Approved | 汉达远 | Mainland China | Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis | Shanghai Henlius Biotech Inc | 2020-12-02 | Arthritis, Juvenile; Arthritis, Rheumatoid; Crohn Disease; Immune System Diseases; Panuveitis; Pediatric Crohn's disease; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing; Uveitis, Intermediate; Uveitis, Posterior | Details | |
| Infliximab | TA-650 | Approved | Johnson & Johnson Innovative Medicine | Remicade, 类克, Avakine, CenTNF | United States | Crohn Disease | Centocor | 1998-08-24 | Aneurysm; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Behcet Syndrome; Bipolar Disorder; Colitis, Ulcerative; Coronavirus Disease 2019 (COVID-19); Crohn Disease; Dermatomyositis; Diabetic macular oedema; Diabetic Retinopathy; Giant Cell Arteritis; Glaucoma; Graft vs Host Disease; Granulomatous Disease, Chronic; Hidradenitis Suppurativa; Inflammatory Bowel Diseases; Macular Edema; Melanoma; Mucocutaneous Lymph Node Syndrome; Non-radiographic axial spondyloarthritis; Palmoplantar pustulosis; Pancreatitis; Parapsoriasis; Pediatric Crohn's disease; Pediatric ulcerative colitis; Plaque psoriasis; Polymyalgia Rheumatica; Polymyositis; Psoriasis; Pulmonary Disease, Chronic Obstructive; Pustular psoriasis; Retinal Detachment; Sarcoidosis; Scleritis; Spondylarthropathies; Spondylitis, Ankylosing; Stevens-Johnson Syndrome; Stroke; Uveitis; Vasculitis; Visual Acuity; Vitreoretinopathy, Proliferative | Details |
| Infliximab biosimilar (Shanghai Biomabs) | CMAB-008; STI-002 | Approved | Shanghai Biomabs Pharmaceuticals Co Ltd | 百类停, 类停 | Mainland China | Colitis, Ulcerative; Spondylitis, Ankylosing; Pediatric Crohn's disease; Crohn Disease; Arthritis, Rheumatoid; Psoriasis | Taizhou Mabtech Pharmaceutical Co Ltd | 2021-07-12 | Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Pediatric Crohn's disease; Psoriasis; Spondylitis, Ankylosing | Details |
| Infliximab biosimilar (Hisun Pharma) | HS-626 | Approved | Zhejiang Hisun Pharmaceutical Co Ltd | Mainland China | Psoriasis | Hisun Biopharmaceutical Co Ltd | 2021-09-24 | Plaque psoriasis; Psoriasis | Details | |
| Infliximab biosimilar (Bionovis/The Instituto Vital Brazil) | Approved | Bionovis, The Instituto Vital Brazil | Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis; Spondylitis, Ankylosing | Details | ||||||
| Etanercept biosimilar (Mylan) | YLB-113 | Approved | Lupin Ltd, Mylan Nv | Nepexto | EU | Spondylarthropathies; Spondylitis, Ankylosing; Arthritis, Psoriatic; Arthritis, Juvenile; Arthritis, Rheumatoid; Plaque psoriasis | Biosimilar Collaborations Ireland Ltd | 2020-05-20 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Plaque psoriasis; Spondylarthropathies; Spondylitis, Ankylosing | Details |
| Pomalidomide | IMID-4047; CDC-394; CC-4047; IMiD-1 | Approved | Celgene Corp | Imnovid, Actimid, Pomalyst/Imnovid, 安跃, Pomalyst | United States | Multiple Myeloma | Bristol-Myers Squibb Company | 2013-02-08 | Anemia, Sickle Cell; Atypical Squamous Cells of the Cervix; Bone Marrow Neoplasms; Carcinoma, Small Cell; Central Nervous System Neoplasms; Glioma; Graft vs Host Disease; Hodgkin Disease; Immunoglobulin Light-chain Amyloidosis; Lung Diseases, Interstitial; Lymphoma, Non-Hodgkin; Medulloblastoma; Multiple Myeloma; Myeloproliferative Disorders; Neurofibromatosis 1; Optic Nerve Glioma; Pancreatic Neoplasms; Plasmacytoma; Polycythemia Vera; Primary Myelofibrosis; Prostatic Neoplasms; Pulmonary Fibrosis; Renal Insufficiency; Sarcoma; Sarcoma, Kaposi; Scleroderma, Systemic; Solid tumours; Thrombocytosis; Waldenstrom Macroglobulinemia | Details |
| Adalimumab biosimilar (Jiangsu Zhonghe/Shanghai Junshi/Jiangsu T-Mab) | UBP-1211; 9MW0113; 9-MW-0113; 9-MW0113; 9MW-0113 | Approved | Jiangsu T-Mab Bio-Pharmaceuticals Co Ltd, Jiangsu Zhonghe Pharmaceutical Technology Co Ltd, Mabwell (Shanghai) Bioscience Co Ltd, Shanghai Junshi Biosciences Co Ltd | 君迈康 | Mainland China | Psoriasis; Arthritis, Rheumatoid; Spondylitis, Ankylosing | Shanghai Junshi Biosciences Co Ltd | 2022-03-01 | Arthritis, Juvenile; Arthritis, Rheumatoid; Crohn Disease; Pediatric Crohn's disease; Psoriasis; Spondylitis, Ankylosing; Uveitis | Details |
| Adalimumab biosimilar (Samsung Bioepis) | SB-5 | Approved | Samsung Bioepis Co Ltd | Imraldi, Hadlima | EU | Pediatric Crohn's disease; Arthritis, Juvenile; Plaque psoriasis; Psoriasis; Pediatric ulcerative colitis; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Hidradenitis Suppurativa; Uveitis | Samsung Bioepis Nl Bv | 2017-08-24 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Hidradenitis Suppurativa; Pediatric Crohn's disease; Pediatric ulcerative colitis; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing; Uveitis | Details |
| Adalimumab biosimilar (Fujifilm Kyowa Kirin Biologics/Mylan) | FKB-327 | Approved | Fujifilm Kyowa Kirin Biologics Co Ltd | Hulio | EU | Hidradenitis Suppurativa; Arthritis, Psoriatic; Uveitis; Colitis, Ulcerative; Crohn Disease; Spondylitis, Ankylosing; Arthritis, Rheumatoid | Biosimilar Collaborations Ireland Ltd | 2018-09-16 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Behcet Syndrome; Colitis, Ulcerative; Crohn Disease; Hidradenitis Suppurativa; Psoriasis; Spondylitis, Ankylosing; Uveitis | Details |
| Etanercept biosimilar (Sunshine Guojian) | 301S | Approved | Jiangsu Xipula Pharmaceutical Co Ltd, Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd | Yisaipu, 益赛普, Etanar, Etacept | Mainland China | Arthritis, Rheumatoid; Psoriasis; Spondylitis, Ankylosing | Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd | 2005-06-20 | Arthritis, Rheumatoid; Psoriasis; Spondylitis, Ankylosing | Details |
| PG-201 | PG-201 | Approved | Viromed | Layla | South Korea | Osteoarthritis | Pmg Pharm Co Ltd | 2012-01-01 | Osteoarthritis; Osteoarthritis, Knee | Details |
| Adalimumab biosimilar (Sandoz) | GP-2017 | Approved | Sandoz | Hefiya, Hyrimoz, Halimatoz | EU | Psoriasis; Hidradenitis Suppurativa; Uveitis; Arthritis, Juvenile; Plaque psoriasis; Colitis, Ulcerative; Crohn Disease; Polyarticular Juvenile Idiopathic Arthritis; Non-radiographic axial spondyloarthritis; Arthritis, Rheumatoid; Spondylitis, Ankylosing | Sandoz Gmbh | 2018-07-26 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Hidradenitis Suppurativa; Non-radiographic axial spondyloarthritis; Plaque psoriasis; Polyarticular Juvenile Idiopathic Arthritis; Psoriasis; Spondylitis, Ankylosing; Uveitis | Details |
| Edaravone/(+)-2-Decanol | SIM-071201 | Approved | Jiangsu Simcere Pharmaceutical Co Ltd | 三贝心, 三贝欣, 先必新, Sanbexin | Mainland China | Stroke | Nanjing Simcere Dongyuan Pharmaceutical Co Ltd | 2020-07-29 | Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain Infarction; Cerebral Hemorrhage; Cognition Disorders; Ischemic Stroke; Stroke | Details |
| Adalimumab biosimilar (CTTQ Pharma) | TQZ-2301; TQZ2301 | Approved | Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd | Mainland China | Arthritis, Rheumatoid; Spondylitis, Ankylosing | Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd | 2022-01-18 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis; Spondylitis, Ankylosing | Details | |
| Infliximab biosimilar (AXXO) | Approved | Axxo | Russian Federation | Crohn Disease; Autoimmune Diseases | Axxo | 2013-01-01 | Autoimmune Diseases; Crohn Disease | Details | ||
| Infliximab biosimilar (Celltrion) | CT-P13; CT-P13 IV; CT-P13 SC; TH-023; INT-023 | Approved | Celltrion Inc | Remsima, Flammegis, Inflectra, ZYMFENTRA, RemsimaSC, Remdantry | EU | Colitis, Ulcerative; Crohn Disease; Psoriasis; Arthritis, Psoriatic; Arthritis, Rheumatoid; Spondylitis, Ankylosing | Celltrion Healthcare Hungary Kft | 2013-09-10 | Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Hidradenitis Suppurativa; Inflammatory Bowel Diseases; Pediatric Crohn's disease; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing | Details |
| Adalimumab biosimilar (Zydus Cadila) | ZRC-3197 | Approved | Zydus Cadila | Exemptia, Adaly | India | Arthritis, Juvenile; Arthritis, Rheumatoid; Arthritis, Psoriatic; Spondylitis, Ankylosing | Zydus Cadila | 2014-12-09 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Spondylitis, Ankylosing | Details |
| Mufemilast | Hemay-005 | Approved | Hainan Hailing Chemipharma Corporation Ltd, Tianjin Hemay Pharmaceutical Co Ltd | 莫米欣 | Mainland China | Plaque psoriasis | Ganzhou Hemei Pharmaceutical Co Ltd | 2025-09-30 | Arthritis, Psoriatic; Behcet Syndrome; Colitis, Ulcerative; Crohn Disease; Dermatitis, Atopic; Plaque psoriasis; Psoriasis; Pulmonary Disease, Chronic Obstructive; Spondylitis, Ankylosing | Details |
| Ozoralizumab | PF-5230896; ATN-103; PF-05230896; TS-152 | Approved | Ablynx Nv | ナノゾラ, Nanozora | Japan | Arthritis, Rheumatoid | Taisho Pharmaceutical Co Ltd | 2022-09-26 | Arthritis, Rheumatoid | Details |
| Opinercept | E-11; ENIA-11 | Approved | Mycenax Biotech Inc, TSH Biopharm Corp Ltd | TuNEX | Taiwan | Arthritis, Rheumatoid | null | 2017-01-01 | Arthritis, Rheumatoid; Spondylitis, Ankylosing | Details |
| Adalimumab biosimilar (Shilpa Biologicals) | SBDM-02 | Approved | Shilpa Biologicals Pvt Ltd | Arthritis, Psoriatic; Arthritis, Rheumatoid; Crohn Disease; Plaque psoriasis; Polyarticular Juvenile Idiopathic Arthritis; Spondylitis, Ankylosing | Details | |||||
| Etanercept biosimilar (Reliance Life Sciences) | Approved | Reliance Life Sciences | Arthritis, Rheumatoid | Details | ||||||
| Adalimumab biosimilar (Wuhan Institute Of Biological) | Approved | Wuhan Institute Of Biological Products Co Ltd | 生爱宁 | Mainland China | Spondylitis, Ankylosing; Psoriasis; Arthritis, Juvenile; Pediatric Crohn's disease; Plaque psoriasis; Crohn Disease; Uveitis; Arthritis, Rheumatoid | Wuhan Institute Of Biological Products Co Ltd | 2025-08-05 | Arthritis, Juvenile; Arthritis, Rheumatoid; Crohn Disease; Pediatric Crohn's disease; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing; Uveitis | Details | |
| Adalimumab biosimilar (Hisun Pharma) | HS-016 | Approved | Zhejiang Hisun Pharmaceutical Co Ltd | 安健宁 | Mainland China | Spondylitis, Ankylosing; Arthritis, Rheumatoid | Hisun Biopharmaceutical Co Ltd | 2019-12-06 | Arthritis, Rheumatoid; Spondylitis, Ankylosing | Details |
| Golimumab biosimilar ( Alvotech) | AV-T05; AVT05 | Approved | Alvotech Swiss Ag | Gobivaz | United Kingdom | Colitis, Ulcerative; Arthritis, Juvenile; Arthritis, Psoriatic; Axial Spondyloarthritis; Arthritis, Rheumatoid | Alvotech Swiss Ag | 2025-11-06 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Axial Spondyloarthritis; Colitis, Ulcerative; Inflammation | Details |
| Infliximab biosimilar (Merck & Co/Samsung Bioepis) | SB-2 | Approved | Merck & Co Inc, Samsung Bioepis Co Ltd | Renflexis, Flixabi | EU | Spondylitis, Ankylosing; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis; Arthritis, Psoriatic | Samsung Bioepis Nl Bv | 2016-05-26 | Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing | Details |
| Andrographolide/Sodium Hydrogen Sulfite | Approved | Bacterial Infections | Details | |||||||
| Etanercept biosimilar (Shanghai Celgen) | Approved | Shanghai Celgen Bio-Pharmaceutical Co Ltd | 强克 | Mainland China | Spondylitis, Ankylosing | Shanghai Celgen Bio-Pharmaceutical Co Ltd | 2011-04-01 | Arthritis, Rheumatoid; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing | Details | |
| Edaravone/(+)-2-Decanol (Yantai Yene/Simcere) | Y-2 | Approved | Simcere Pharmaceutical Group Ltd, Yantai Yene Pharma Co Ltd | Mainland China | Stroke | Jiangsu Simcere Pharmaceutical Co Ltd | 2024-12-01 | Cerebral Hemorrhage; Cognitive Dysfunction; Intracranial Hemorrhages; Ischemic Stroke; Stroke | Details | |
| Adalimumab biosimilar (Coherus BioSciences) | CHS-1420 | Approved | Coherus Biosciences Inc | Yusimry | United States | Crohn Disease; Plaque psoriasis; Arthritis, Juvenile; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Psoriatic; Colitis, Ulcerative | Coherus Biosciences Inc | 2021-12-17 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing | Details |
| Infliximab biosimilar (Nichiiko/Aprogen) | NI-071; GS-071; GS-07; AP-07 | Approved | Aprogen, Nichi-Iko Pharmaceutical Co Ltd | Japan | Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis | Nichi-Iko Pharmaceutical Co Ltd | 2017-09-27 | Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis | Details | |
| Thalidomide | NSC-66847; NSC-527179; K-17; FPF-300; FPF300 | Approved | Celgene Corp | Talizer, Thalidomide Celgene, Thalidomide Pharmion, Synovir, Thalomid, Thaled | Mainland China | Leprosy, Lepromatous; Multiple Myeloma | Changzhou Pharmaceutical Factory | 1982-01-01 | Acquired Immunodeficiency Syndrome; Adenocarcinoma, Clear Cell; Adenoma, Islet Cell; Amyotrophic Lateral Sclerosis; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Anemia, Sideroblastic; Angiodysplasia; Appendiceal Neoplasms; Arachnoiditis; Arteriovenous Malformations; Axial Spondyloarthritis; beta-Thalassemia; Burning Mouth Syndrome; Carcinoid Tumor; Carcinoma, Adenosquamous; Carcinoma, Hepatocellular; Cholangitis, Sclerosing; Colorectal Neoplasms; Cough; Endometrial Neoplasms; Endometriosis; Epilepsy; Erythema Nodosum; Gastric Antral Vascular Ectasia; Gastrointestinal Hemorrhage; Genetic Diseases, Inborn; Glioma; Graft vs Host Disease; Head and Neck Neoplasms; Hemoglobinopathies; HIV Infections; HIV Wasting Syndrome; Hodgkin Disease; Hormone-Resistant Prostate Neoplasms; Hypertension, Portal; Idiopathic Pulmonary Fibrosis; Kidney Neoplasms; Leiomyosarcoma; Leprosy, Lepromatous; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelomonocytic, Chronic; Liver Neoplasms; Lung Neoplasms | Details |
| Adalimumab biosimilar (Pfizer) | PF-06410293 | Approved | Pfizer Inc | Abrilada, Fyzoclad, Amsparity | United States | Crohn Disease; Psoriasis; Arthritis, Rheumatoid; Colitis, Ulcerative; Arthritis, Juvenile; Arthritis, Psoriatic; Spondylitis, Ankylosing | Pfizer Inc | 2019-11-15 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Hidradenitis Suppurativa; Psoriasis; Spondylitis, Ankylosing; Uveitis | Details |
| Etanercept biosimilar (Hisun-Pfizer Pharmaceuticals) | Approved | Hisun-Pfizer | AnBaiNuo, 安佰诺 | Mainland China | Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis | Wyeth Europa Ltd | 2010-02-26 | Arthritis, Psoriatic; Arthritis, Rheumatoid; Psoriasis; Spondylitis, Ankylosing | Details | |
| Adalimumab | ABT-D2E7; LU-200134; D2E7 | Approved | Abbvie Inc | Humira, Trudexa, 修美乐 | United States | Arthritis, Rheumatoid | Abbvie Inc | 2002-12-31 | Arthritis; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Axial Spondyloarthritis; Carcinoma, Non-Small-Cell Lung; Choroidal Neovascularization; Colitis, Ulcerative; Coronavirus Disease 2019 (COVID-19); Crohn Disease; Cystitis, Interstitial; Diabetic Retinopathy; Dupuytren Contracture; Generalised pustular psoriasis; Glomerulosclerosis, Focal Segmental; Hidradenitis Suppurativa; Mucopolysaccharidosis I; Mucopolysaccharidosis II; Mucopolysaccharidosis VI; Nephrosis, Lipoid; Nephrotic Syndrome; Osteoarthritis; Osteoarthritis, Knee; Pain; Panuveitis; Pediatric Crohn's disease; Periarthritis; Plaque psoriasis; Pouchitis; Prostatic Hyperplasia; Psoriasis; Pyoderma Gangrenosum; REM Sleep Behavior Disorder; Sarcoidosis; Spondylarthritis; Spondylitis, Ankylosing; Uveitis; Uveitis, Intermediate; Uveitis, Posterior | Details |
| Etanercept biosimilar (Qilu Pharmaceutical) | QL-0902 | Approved | Qilu Pharmaceutical Co Ltd | Mainland China | Qilu Pharmaceutical Co Ltd | 2023-12-19 | Arthritis, Rheumatoid; Spondylitis, Ankylosing | Details | ||
| Etanercept biosimilar (Samsung Bioepis) | SB-4 | Approved | Samsung Bioepis Co Ltd | Eticovo, Benepali | EU | Arthritis, Psoriatic; Arthritis, Rheumatoid; Plaque psoriasis; Spondylitis, Ankylosing | Samsung Bioepis Nl Bv | 2016-01-13 | Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing | Details |
| Etanercept | TNR-001 | Approved | Amgen Inc, Pfizer Inc | Lifmior, 恩利, Enbrel | EU | Arthritis, Juvenile; Plaque psoriasis; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Psoriatic | Pfizer Europe Ma Eeig | 2000-02-02 | Acute Lung Injury; Alzheimer Disease; Anorexia; Arthritis; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Bone Neoplasms; Bronchiolitis Obliterans; Cachexia; Chronic Urticaria; Diabetes Mellitus, Type 1; Fanconi Anemia; Graft vs Host Disease; Granulomatosis with Polyangiitis; Hidradenitis Suppurativa; HIV Infections; Inflammation; Kidney Failure, Chronic; Leukemia; Lichen Planus; Lung Neoplasms; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Discoid; Metabolic Syndrome; Myositis, Inclusion Body; Neoplasm Metastasis; Non-radiographic axial spondyloarthritis; Obesity; Plaque psoriasis; Prostatic Neoplasms; Psoriasis; Pulmonary Fibrosis; Rejection of lung transplantation; Respiratory Distress Syndrome, Adult; Sjogren's Syndrome; Solid tumours; Spondylarthritis; Spondylitis, Ankylosing; Stomatitis; Synovitis; Temporomandibular Joint Disorders; Tinnitus; Uveitis; Vasculitis; Vitiligo | Details |
Product Reviews
n***l2025-11-20
0People LikeLove the consistent activity and freeze/thaw stability! very quick shipping- P***s2024-11-15 3People LikeWe used this product to conduct binding affinity measurements with molecular modulators that were designed to bind to TNFα In Vitro. Experiment applied was Microscale Thermophoresis that detects binding and, with dilution series, binding affinity between TNFα and test molecule. Results showed low micro molar binding, which showed that TNFα and test molecule behaved as we hoped for! Now we ordered more of this protein for further tests
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